Results 81 to 90 of about 29,735,084 (200)
Galectin-1 as an oncotarget in gliomas and melanomas
Oncotarget, 2011 Galectin-1 is a 14.5-kDa β-galactoside-binding protein that belongs to a 15-member protein family expressed by many different cell types. It exerts major roles in the immune system [1,2] and is involved in the progression of various cancer types [3], including melanomas and gliomas [4].
Lefranc, Florence +2 more
openaire +4 more sources
The Third Dimension of Reading the Sugar Code by Lectins [PDF]
, 2013 Coding of biological information is not confined to nucleic acids and proteins. Endowed with the highest level of structural versatility among biomolecules, the glycan chains of cellular glycoconjugates are well-suited to generate molecular messages ...
Murphy, Paul +7 more
core +1 more source
, 2009 Galectin-1, the prototype of a family of beta-galactoside-binding proteins, has been implicated in a wide variety of biological processes. Data presented herein show that galectin-1 stimulates monocyte migration in a dose-dependent manner but is not ...
Rohit R Ghurye (16048214) +3 more
core +1 more source
Galectin-3 promotes EV71 infection.
, 2016 (A) Using TALEN, ablation of the galectin-3 gene was performed in RD cells. Two clones of galectin-3 knock-out (G3KO) RD cells were selected. Protein expression of galectin-3 was examined in cell lysates from RD cells and two G3KO clones (G3KO-A1 and ...
Yungling Lee (3454598) +7 more
core +1 more source
, 2011 Background: A growing body of evidence links macrophage activation and fibrosis to the pathogenesis of heart failure (HF). Galectin-3 is one of the most likely mediators between macrophage activation and myocardial fibrosis.
LIN, YEN-HUNG;LIN, LIAN-YU;WU, YEN-WEN;CHIEN, KUO-LIONG;LEE, CHII-MING;HSU, RON-BIN;CHAO, CHIA-LUN;WANG, SHOEI-SHEN;HSEIN, YENH-CHEN;LIAO, LIN-CHU;HO, YI-LWUN;CHEN, MING-FONG +1 more
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Glycosylation pattern of brush border-associated glycoproteins in enterocyte-like cells: involvement of complex-type N-glycans in apical trafficking [PDF]
, 2009 We have previously reported that galectin-4, a tandem repeat-type galectin, regulates the raft-dependent delivery of glycoproteins to the apical brush border membrane of enterocyte-like HT-29 cells.
Huet, Guillemette +8 more
core +1 more source
Cancer MedicineBackground In renal cell carcinoma (RCC), no clinically available biomarker has been utilized for checkpoint inhibitor immunotherapy (IO) + tyrosine kinase inhibitor (TKI) combinations.
Jiajun Wang +5 more
doaj +1 more source
Galectin-3 suppresses mucosal inflammation and reduces disease severity in experimental colitis
, 2017 Galectin-3, a member of the beta-galactoside-binding lectin family, expresses in many different immune cells and modulates broad biological functions including cell adhesion, cell activation, cell growth, apoptosis, and inflammation. However, the role of
許秉寧 +1 more
core +1 more source
CellsBreast cancer is a highly heterogeneous disease; hence, it is crucial to understand its biology and identify new targets for the development of effective treatments. Galectin-1 is known to play an oncogenic role in breast cancer progression.
Ju Yeon Kim +11 more
doaj +1 more source
VML, uma lectina com afinidade por galactose isolada das sementes de vatairea macrocarpa, pode induzir resposta neurotóxicas [PDF]
, 2013 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-graduação em Bioquímica, Florianópolis, 2013Lectinas são proteínas que se ligam a carboidratos presentes em glicoconjugados podendo regular ...
Gonçalves, Filipe Marques
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