Results 251 to 260 of about 9,167 (280)

Galectin-8: a complex sub-family of galectins (Review)

International Journal of Molecular Medicine, 2001
Galectins are animal lectins, that can specifically bind beta-galactosides. Twelve galectins have been described in vertebrates, belonging to three different groups: prototype, tandem-repeat and chimeric. These proteins seem to be involved in cellular interactions and neoplastic transformations.
N, Bidon, F, Brichory, P, Bourguet, J P, Le Pennec, L, Dazord   +4 more
openaire   +2 more sources

Galectin-3 and metastasis

Glycoconjugate Journal, 2002
Galectin-3, a 31 kDa member of the beta-galactoside-binding proteins, is an intracellular and extracellular lectin which interacts with intracellular glycoproteins, cell surface molecules and extracellular matrix proteins. Galectin-3 is expressed widely in epithelial and immune cells and its expression is correlated with cancer aggressiveness and ...
Yukinori, Takenaka, Tomoharu, Fukumori, Avraham, Raz   +2 more
openaire   +2 more sources

Galectin-3 in cancer

Clinica Chimica Acta, 2014
Galectin-3 (Gal-3) plays important roles in cell proliferation, adhesion, differentiation, angiogenesis and apoptosis in normal and pathologic tissues. Accumulated evidences indicate that Gal-3 is closely involved in tumor cell transformation, migration, invasion and metastasis. In this review, the associations of the expression and localization of Gal-
Lin, Song, Jian-wu, Tang, Lawrence, Owusu, Ming-Zhong, Sun, Jun, Wu, Jun, Zhang   +5 more
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The Levels of Expression of Galectin‐3, But Not of Galectin‐1 and Galectin‐8, Correlate With Apoptosis in Human Cholesteatomas

The Laryngoscope, 2001
AbstractObjectives To investigate whether galectins 1, 3, and 8 are expressed in human cholesteatomas and whether any such expression does correlate with the level of apoptosis, which is, as we have previously shown, predictive of recurrence. 7Study Design The analysis of 52 cholesteatomas resected by the same surgeon by means of canal wall up and ...
Sheikholeslam-zadeh, R, Decaestecker, Christine, Delbrouck, Carine, Danguy, André, Salmon, Isabelle, Zick, Yehiel, Kaltner, Herbert, Hassid, Sergio, Gabius, Hans-Joachim, Kiss, Robert, Choufani, Georges   +10 more
openaire   +3 more sources

Galectins and urological cancer

Journal of Cellular Biochemistry, 2003
AbstractGalectins are a family of proteins defined by their affinity for β‐galactoside and by their conserved sequence. Each galectins exhibits a specific expression pattern in various tissues and their expression is regulated during development. Their expression is altered in many types of cancers and non‐cancerous disorders.
Natsuo, Oka, Yukinori, Takenaka, Avraham, Raz   +2 more
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Examination of the Role of Galectins and Galectin Inhibitors in Endothelial Cell Biology

2014
The growth of new blood vessels is a key event in many (patho)physiological processes, including embryogenesis, wound healing, inflammatory diseases, and cancer. Neovascularization requires different, well-coordinated actions of endothelial cells, i.e., the cells lining the luminal side of all blood vessels.
Schulkens, I.A.E., Kleibeuker, E.A., Castricum, K.C.M., Griffioen, A.W., Thijssen, V.L.J.L.   +4 more
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Roles of galectins in vivo

Biochemical Society Symposia, 2002
The mutational analysis of the galectin family is shedding a different light of this class of molecules. On the one hand, it appears that galectin 1 and galectin 3 are not required for the survival of mice in normal animal house conditions, while on the other hand, there seems to be several subtle, but very complex, consequences of lacking galectins ...
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Galectins in Regulation of Apoptosis

2011
The term “galectins” was given in 1994 to a family of animal lectins that bind to β-galactosides and contain comparable sequences of amino acids in their genes and proteins [1]. At that time, there were just four identified members, but now 15 members have been described in mammals, with similar proteins found in various animal species, as well as in ...
Fu-Tong, Liu, Ri-Yao, Yang, Jun, Saegusa, Huan-Yuan, Chen, Daniel K, Hsu   +4 more
openaire   +2 more sources

Inhibition of galectins in cancer: Biological challenges for their clinical application

Frontiers in Immunology, 2023
Diego Läderach, Daniel Compagno, Compagno Daniel   +2 more
exaly  

Galectins Control mTOR in Response to Endomembrane Damage

Molecular Cell, 2018
Yakubu Princely Abudu, Aurore Claude-Taupin, Seong Won Choi   +2 more
exaly