Results 61 to 70 of about 197,067 (301)

Inhibition of growth of hepatocellular carcinoma by co-delivery of anti-PD-1 antibody and sorafenib using biomimetic nano-platelets

BMC Cancer
Background Traditional nanodrug delivery systems have some limitations, such as eliciting immune responses and inaccuracy in targeting tumor microenvironments.
Xuanbo Da, Bangping Cao, Jiantao Mo, Yukai Xiang, Hai Hu, Chen Qiu, Cheng Zhang, Beining Lv, Honglei Zhang, Chuanqi He, Yulong Yang   +10 more
doaj   +1 more source

Alteration of gut microbiota in association with cholesterol gallstone formation in mice

BMC Gastroenterology, 2017
Background The gut microbiome exerts extensive roles in metabolism of nutrients, pharmaceuticals, organic chemicals. Little has been known for the role of gut microbiota in regulating cholesterol and bile acids in association with gallstone formation ...
Qihan Wang, Long Jiao, Chuanqi He, Haidong Sun, Qu Cai, Tianquan Han, Hai Hu   +6 more
doaj   +1 more source

LncRNA‐PAGBC acts as a microRNA sponge and promotes gallbladder tumorigenesis

EMBO Reports, 2017
Long noncoding RNAs (lncRNAs) play roles in the development and progression of many cancers; however, the contributions of lncRNAs to human gallbladder cancer (GBC) remain largely unknown.
Xiang-song Wu, F. Wang, Huai-feng Li, Yun-ping Hu, Lin Jiang, Fei Zhang, Maolan Li, Xu-an Wang, Yun-peng Jin, Yi-Jian Zhang, W. Lu, Wen-guang Wu, Yi-Jun Shu, H. Weng, Yang Cao, Run-fa Bao, Haibin Liang, Zheng Wang, Yi-Chi Zhang, W. Gong, Lei Zheng, Shuhan Sun, Ying-bin Liu   +22 more
semanticscholar   +1 more source

A contribution to the anatomy of two rare cetacean species: The hourglass dolphin (Cephalorhynchus cruciger) and the spectacled porpoise (Phocoena dioptrica)

The Anatomical Record, EarlyView.
Abstract The anatomical description of the hourglass dolphin (Cephalorhynchus cruciger) and the spectacled porpoise (Phocoena dioptrica) remains largely unexplored, due to limited specimen availability and preservation challenges. This study employed digital imaging techniques, conventional histology, and computed tomography to provide visualization of
Jean‐Marie Graïc, Tommaso Gerussi, Bruno Cozzi, Rebecca M. Boys, Brian Chin Wing Kot, Matthew R. Perrott, Kane Fleury, Tabris Yik To Chung, Henry Chun Lok Tsui, Emma Burns, Trudi Webster, Stuart Hunter, Emma L. Betty, Odette Howarth, Carolina Loch, Sophie White, Steve Dawson, William Rayment, Ros Cole, Derek Cox, Tom Waterhouse, Hannah Hendriks, Anton van Helden, Muriel Johnstone, Ramari Oliphant Stewart, R. Ewan Fordyce, Karen A. Stockin   +26 more
wiley   +1 more source

Regulation of Human Adipose Tissue Activation, Gallbladder Size, and Bile Acid Metabolism by a β3-Adrenergic Receptor Agonist

Diabetes, 2018
β3-adrenergic receptor (AR) agonists are approved to treat only overactive bladder. However, rodent studies suggest that these drugs could have other beneficial effects on human metabolism. We performed tissue receptor profiling and showed that the human
Alison S. Baskin, J. Linderman, R. Brychta, Suzanne McGehee, Esti Anflick-Chames, C. Cero, James W. Johnson, Alana O'mara, Laura A. Fletcher, Brooks P. Leitner, Courtney J. Duckworth, Shan Huang, H. Cai, H. Garraffo, C. Millo, W. Dieckmann, V. Tolstikov, Emily Y. Chen, Fei Gao, N. Narain, M. Kiebish, P. Walter, P. Herscovitch, Kong Y. Chen, A. Cypess   +24 more
semanticscholar   +1 more source

Gallbladder Bilharziasis [PDF]

HPB Surgery, 1996
A 30 years old man presented with symptoms of Bilharziasis. Ultrasound showed gallstones in the gallbladder which was removed laproscopically, heavy bilharzial infection was detected in the gallbladder tissue. The first case in Saudi Arabia is reported. A Review of the world literatures since 1966 about the subject is presented and different aspects of
openaire   +2 more sources

The anatomical knowledge of Namibian school children

Anatomical Sciences Education, EarlyView.
Abstract The public has limited knowledge of key organs and anatomical structures. The lack of anatomical knowledge and understanding can hinder time to access healthcare, quality of care, and treatment outcomes. The current study investigated the anatomical knowledge among Namibian children by comparing 8 school grades—4 to 12, which covers children ...
Adam M. Taylor, Lojandrie Kirsten, Luigi Sedda, Quenton Wessels   +3 more
wiley   +1 more source

Mediating role of emotional intelligence in the relationship between dual work stress and reflective ability among junior nurses

BMC Nursing
Background Junior nurses constitute the backbone of the nursing workforce, and their reflective ability is essential for clinical decision-making, as well as for driving innovation and improvement in nursing practices. Although numerous studies emphasize
Mingfang Zhang, Junxian Wu, Yanting Yang, Jingru Song, Qin Shen   +4 more
doaj   +1 more source

A Potential Pitfall in POCUS of the Gallbladder: Beware of the Duodenum

POCUS Journal, 2022
It is estimated that 20 million people in the United States have gallbladder disease. Of the patients who present to the Emergency Department (ED) with abdominal pain, 3-10% have acute cholecystitis [1].
Fan Yang, Brian Kohen, Sowmya Sanapala, Michael Halperin   +3 more
doaj   +1 more source

Assessing transporter‐mediated rifampin–linezolid interaction using physiologically‐based pharmacokinetic modelling

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims The study aims to develop a physiologically‐based pharmacokinetic (PBPK) model to quantitatively evaluate the role of ATP‐binding cassette sub‐family B member 1 (ABCB1) and ATP‐binding cassette super‐family G member 2 (ABCG2) in the drug–drug interaction (DDI) between rifampin and linezolid and to predict the impact of high‐dose rifampin ...
Hoang Dat Nguyen, Vinh Hoa Pham, Richard M. Hoglund, Joel Tarning, Junjie Ding   +4 more
wiley   +1 more source