Results 31 to 40 of about 4,466,693 (321)

Neoadjuvant therapy for gallbladder cancer: current status and challenge [PDF]

open access: yesWaike lilun yu shijian, 2023
Gallbladder cancer is one of highly malignant digestive system tumors with insidious symptoms, rapid progression, and poor prognosis. Although radical resective surgery is the only possible curative way for gallbladder cancer, most patients have lost the
XING Ying, CHENG Shi
doaj   +1 more source

Phase Ib study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis

open access: yesHepatology, EarlyView., 2022
Phase 1b study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis. Abstract Background and Aims We evaluated the efficacy and safety of the antiangiogenic tyrosine kinase inhibitor anlotinib plus TQB2450, a programmed death‐ligand 1 inhibitor in pretreated advanced biliary tract cancers (BTCs ...
Jun Zhou   +13 more
wiley   +1 more source

MBD1 promotes the malignant behavior of gallbladder cancer cells and induces chemotherapeutic resistance to gemcitabine

open access: yesCancer Cell International, 2019
Background Methyl-CpG binding domain protein 1 (MBD1), which couples DNA methylation to transcriptional repression, has been implicated in transcriptional regulation, heterochromatin formation, genomic stability, cell cycle progression and development ...
Liu Wensheng   +8 more
doaj   +1 more source

Gallbladder cancer-associated fibroblasts promote vasculogenic mimicry formation and tumor growth in gallbladder cancer via upregulating the expression of NOX4, a poor prognosis factor, through IL-6-JAK-STAT3 signal pathway

open access: yesJournal of experimental & clinical cancer research : CR, 2020
Background Cancer-associated fibroblasts (CAFs) and vasculogenic mimicry (VM) play important roles in the occurrence and development of tumors. However, the relationship between CAFs and VM formation, especially in gallbladder cancer (GBC) has not been ...
Musu Pan   +5 more
semanticscholar   +1 more source

MicroRNA-125b predicts clinical outcome and suppressed tumor proliferation and migration in human gallbladder cancer

open access: yesTumor Biology, 2017
We intended to investigate the functional role and clinical relevance of microRNA-125b in human gallbladder cancer. Quantitative real-time polymerase chain reaction was used to examine microRNA-125b expression in gallbladder cancer cell lines, and 79 ...
Liang Yang   +4 more
doaj   +1 more source

Role of tumour location and surgical extent on prognosis in T2 gallbladder cancer: an international multicentre study

open access: yesBritish Journal of Surgery, 2020
In gallbladder cancer, stage T2 is subdivided by tumour location into lesions on the peritoneal side (T2a) or hepatic side (T2b). For tumours on the peritoneal side (T2a), it has been suggested that liver resection may be omitted without compromising the
W. Kwon   +30 more
semanticscholar   +1 more source

LapSeg3D: Weakly Supervised Semantic Segmentation of Point Clouds Representing Laparoscopic Scenes [PDF]

open access: yes, 2022
The semantic segmentation of surgical scenes is a prerequisite for task automation in robot assisted interventions. We propose LapSeg3D, a novel DNN-based approach for the voxel-wise annotation of point clouds representing surgical scenes. As the manual annotation of training data is highly time consuming, we introduce a semi-autonomous clustering ...
arxiv   +1 more source

Gallbladder Cancer

open access: yes, 2023
Gallbladder carcinoma is a form of cancer that develops in the gallbladder, an organ located beneath the liver. This condition poses a clinical challenge due to its late diagnosis and aggressive tumor behavior. Risk factors include the presence of gallstones, advanced age, and obesity.
de Werra, Carlo   +8 more
openaire   +2 more sources

Gallstones, Body Mass Index, C‐Reactive Protein, and Gallbladder Cancer: Mendelian Randomization Analysis of Chilean and European Genotype Data

open access: yesHepatology, 2020
Gallbladder cancer (GBC) is a neglected disease with substantial geographical variability: Chile shows the highest incidence worldwide, while GBC is relatively rare in Europe.
Carol Barahona Ponce   +47 more
semanticscholar   +1 more source

Acetylation stabilizes stathmin1 and promotes its activity contributing to gallbladder cancer metastasis

open access: yesCell Death Discovery, 2022
Gallbladder cancer is the most common biliary tract malignant tumor with highly metastatic characters and poor prognosis. However, the underlying mechanism remains unclear. Stathmin1 is ubiquitous phosphoprotein, regulating microtubule stabilization.
Kun Fan   +11 more
doaj   +1 more source

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