Results 11 to 20 of about 44,009 (270)

Dietary Phytochemical Index and Risk of Gallstone Disease: A Case-Control Study. [PDF]

Health Sci Rep
Ghaeminejad Z, Bahreini Boroujeni LZ, Javaheri-Tafti F, Abbas-Hashemi SA, Hekmatdoost A, Ghorbani M, Sadeghi A, Yari Z.   +7 more
europepmc   +3 more sources

Factors related to intestine have a role in prevention and treatment for gallstone disease [PDF]

Waike lilun yu shijian, 2023
Gallstone is a common surgical disease. The factors which related to intestine during the process of gallstone formation have attracted increasing attention.
JIANG Zhaoyan, SHEN Weiyi, HU Hai
doaj   +1 more source

Gallstone disease [PDF]

Journal of Internal Medicine, 2007
Abstract.Gallstone disease is one of the most prevalent gastrointestinal diseases with a substantial burden to health care systems that is supposed to increase in ageing populations at risk. Aetiology and pathogenesis of cholesterol gallstones still are not well defined, and strategies for prevention and efficient nonsurgical therapies are missing ...
H-U, Marschall, C, Einarsson
openaire   +2 more sources

Dietary diosgenin transcriptionally down-regulated intestinal NPC1L1 expression to prevent cholesterol gallstone formation in mice

Journal of Biomedical Science, 2023
Background Cholesterol gallstone disease is a common disease. Reducing cholesterol burden is important to prevent/treat gallstone. In this study, we investigated the application of diosgenin (DG) to prevent the formation of gallstone in mice.
Weiyi Shen, Wentao Shao, Qihan Wang, Bo Wang, Gang Zhao, Aihua Gu, Zhaoyan Jiang, Hai Hu   +7 more
doaj   +1 more source

Association between statin use and risk of gallstone disease and cholecystectomy: a meta-analysis of 590,086 patients [PDF]

PeerJ, 2023
Background Statins have been reported to reduce the risk of gallstone disease. However, the impacts of different durations of statin use on gallstone disease have not been clarified.
Yu Chang, Hong-Min Lin, Kuan-Yu Chi, Wan-Ying Lin, Tsung-Ching Chou   +4 more
doaj   +2 more sources

IGF2BP3 drives gallbladder cancer progression by m6A-modified CLDN4 and inducing macrophage immunosuppressive polarization

Translational Oncology, 2023
Introduction: N6-methyladenosine (m6A) is an emerging epigenetic modification, which plays a crucial role in the development of cancer. Nevertheless, the underlying mechanism of m6A-associated proteins and m6A modification in gallbladder cancer remains ...
Jian Qin, Zheng Cui, Jingyi Zhou, Bosen Zhang, Ruiqi Lu, Youcheng Ding, Hai Hu, Jingli Cai   +7 more
doaj   +1 more source

METTL3 promotes glycolysis and cholangiocarcinoma progression by mediating the m6A modification of AKR1B10

Cancer Cell International, 2022
Objective N6-methyladenosine (m6A) RNA methylation is involved in governing the mechanism of tumor progression. We aimed to excavate the biological role and mechanism of the m6A methyltransferase METTL3 in cholangiocarcinoma (CCA).
Jingli Cai, Zheng Cui, Jingyi Zhou, Bosen Zhang, Ruiqi Lu, Youcheng Ding, Hai Hu   +6 more
doaj   +1 more source

Myeloid p38 activation maintains macrophage–liver crosstalk and BAT thermogenesis through IL‐12–FGF21 axis

Hepatology, EarlyView., 2022
Physiological activation of myeloid p38 controls macrophage IL‐12 production and crosstalk to the liver by modulating hepatic FGF21, and subsequently, brown adipose tissue thermogenesis during obesity Abstract Obesity features excessive fat accumulation in several body tissues and induces a state of chronic low‐grade inflammation that contributes to ...
María Crespo, Ivana Nikolic, Alfonso Mora, Elena Rodríguez, Luis Leiva‐Vega, Aránzazu Pintor‐Chocano, Daniel Horrillo, Lourdes Hernández‐Cosido, Jorge L. Torres, Eva Novoa, Rubén Nogueiras, Gema Medina‐Gómez, Miguel Marcos, Magdalena Leiva, Guadalupe Sabio   +14 more
wiley   +1 more source

Free fatty acids and triglyceride change in the gallbladder bile of gallstone patients with pancreaticobiliary reflux

Lipids in Health and Disease, 2021
Background Pancreaticobiliary reflux (PBR) causes chronic inflammation of the gallbladder mucosa and changes in the bile components, which are known to promote gallstone formation.
Yukai Xiang, Xiangyu Kong, Cheng Zhang, Chuanqi He, Jingli Cai, Ruiqi Lu, Bosen Zhang, Liu Lu, Yulong Yang   +8 more
doaj   +1 more source

Gut microbiota promotes cholesterol gallstone formation by modulating bile acid composition and biliary cholesterol secretion

Nature Communications, 2022
Metabolic conditions associated with alterations of the gut microbiome, such as obesity and diabetes, predispose to gallstone disease. Here the authors demonstrate that the gut microbiome, in particular the genus Desulfovibrionale, contribute to ...
Hai Hu, Wentao Shao, Qian Liu, Ning Liu, Qihan Wang, Jin Xu, Xin Zhang, Zhenkun Weng, Qifan Lu, Long Jiao, Chaobo Chen, Haidong Sun, Zhaoyan Jiang, Xiaoping Zhang, Aihua Gu   +14 more
doaj   +1 more source