Results 11 to 20 of about 32,729 (195)

Veillonella, Neisseria, Prevotella, and Lachnoanaerobaculum enrichment in salivary microbiome predicts gallstone disease [PDF]

open access: yesEuropean Journal of Medical Research
Introduction Gallstone disease (GSD) is a common hepatobiliary disorder influenced by bile composition, biliary drainage, and gallbladder motility. Emerging evidence suggests that oral microbiota may contribute to GSD development, but its role remains ...
Ruiqi Lu   +7 more
doaj   +2 more sources

Factors related to intestine have a role in prevention and treatment for gallstone disease [PDF]

open access: yesWaike lilun yu shijian, 2023
Gallstone is a common surgical disease. The factors which related to intestine during the process of gallstone formation have attracted increasing attention.
JIANG Zhaoyan, SHEN Weiyi, HU Hai
doaj   +1 more source

Gallstone disease [PDF]

open access: yesJournal of Internal Medicine, 2007
Abstract.Gallstone disease is one of the most prevalent gastrointestinal diseases with a substantial burden to health care systems that is supposed to increase in ageing populations at risk. Aetiology and pathogenesis of cholesterol gallstones still are not well defined, and strategies for prevention and efficient nonsurgical therapies are missing ...
H-U, Marschall, C, Einarsson
openaire   +2 more sources

Dietary diosgenin transcriptionally down-regulated intestinal NPC1L1 expression to prevent cholesterol gallstone formation in mice

open access: yesJournal of Biomedical Science, 2023
Background Cholesterol gallstone disease is a common disease. Reducing cholesterol burden is important to prevent/treat gallstone. In this study, we investigated the application of diosgenin (DG) to prevent the formation of gallstone in mice.
Weiyi Shen   +7 more
doaj   +1 more source

Myeloid p38 activation maintains macrophage–liver crosstalk and BAT thermogenesis through IL‐12–FGF21 axis

open access: yesHepatology, EarlyView., 2022
Physiological activation of myeloid p38 controls macrophage IL‐12 production and crosstalk to the liver by modulating hepatic FGF21, and subsequently, brown adipose tissue thermogenesis during obesity Abstract Obesity features excessive fat accumulation in several body tissues and induces a state of chronic low‐grade inflammation that contributes to ...
María Crespo   +14 more
wiley   +1 more source

Gallstone Disease and Microbiome [PDF]

open access: yesMicroorganisms, 2020
Gallstone disease (GSD) has, for many years, remained a high-cost, socially significant public health problem. Over the past decade, a number of studies have been carried out—both in humans and in animal models—confirming the role of the microbiota in various sections of the gastrointestinal tract as a new link in the etiopathogenesis of GSD.
Irina N. Grigor’eva   +1 more
openaire   +3 more sources

METTL3 promotes glycolysis and cholangiocarcinoma progression by mediating the m6A modification of AKR1B10

open access: yesCancer Cell International, 2022
Objective N6-methyladenosine (m6A) RNA methylation is involved in governing the mechanism of tumor progression. We aimed to excavate the biological role and mechanism of the m6A methyltransferase METTL3 in cholangiocarcinoma (CCA).
Jingli Cai   +6 more
doaj   +1 more source

Association between statin use and risk of gallstone disease and cholecystectomy: a meta-analysis of 590,086 patients [PDF]

open access: yesPeerJ, 2023
Background Statins have been reported to reduce the risk of gallstone disease. However, the impacts of different durations of statin use on gallstone disease have not been clarified.
Yu Chang   +4 more
doaj   +2 more sources

IGF2BP3 drives gallbladder cancer progression by m6A-modified CLDN4 and inducing macrophage immunosuppressive polarization

open access: yesTranslational Oncology, 2023
Introduction: N6-methyladenosine (m6A) is an emerging epigenetic modification, which plays a crucial role in the development of cancer. Nevertheless, the underlying mechanism of m6A-associated proteins and m6A modification in gallbladder cancer remains ...
Jian Qin   +7 more
doaj   +1 more source

The Treatment of Gallstone Disease [PDF]

open access: yesDeutsches Ärzteblatt international, 2020
Gallstone disease affects up to 20% of the European population, and cholelithiasis is the most common reason for hospitalization in gastroenterology.This review is based on pertinent publications retrieved by a selective search of the literature, including the German clinical practice guidelines on the diagnosis and treatment of gallstones and ...
Carsten, Gutt   +2 more
openaire   +2 more sources

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