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Gallstone Disease and Microbiome [PDF]
Microorganisms, 2020 Gallstone disease (GSD) has, for many years, remained a high-cost, socially significant public health problem. Over the past decade, a number of studies have been carried out—both in humans and in animal models—confirming the role of the microbiota in various sections of the gastrointestinal tract as a new link in the etiopathogenesis of GSD.
Romanova Tatyana
exaly +4 more sources
Veillonella, Neisseria, Prevotella, and Lachnoanaerobaculum enrichment in salivary microbiome predicts gallstone disease [PDF]
European Journal of Medical ResearchIntroduction Gallstone disease (GSD) is a common hepatobiliary disorder influenced by bile composition, biliary drainage, and gallbladder motility. Emerging evidence suggests that oral microbiota may contribute to GSD development, but its role remains ...
Ruiqi Lu +7 more
doaj +2 more sources
Prevalence of gallstone disease and its association with altitude and ethnicity among employee health check-upers in the Qinghai-Tibet Plateau [PDF]
BMC GastroenterologyObjective This study aimed to investigate the prevalence of gallstone disease among health check-upers (employees) in the Qinghai-Tibet Plateau and clarify the independent effects of altitude, ethnicity, and their interaction on gallstone disease risk ...
Shenggui Qi +6 more
doaj +2 more sources
Factors related to intestine have a role in prevention and treatment for gallstone disease [PDF]
Waike lilun yu shijian, 2023 Gallstone is a common surgical disease. The factors which related to intestine during the process of gallstone formation have attracted increasing attention.
JIANG Zhaoyan, SHEN Weiyi, HU Hai
doaj +1 more source
Journal of Internal Medicine, 2007 Abstract.Gallstone disease is one of the most prevalent gastrointestinal diseases with a substantial burden to health care systems that is supposed to increase in ageing populations at risk. Aetiology and pathogenesis of cholesterol gallstones still are not well defined, and strategies for prevention and efficient nonsurgical therapies are missing ...
H-U, Marschall, C, Einarsson
openaire +2 more sources
Hepatology, EarlyView., 2022 Physiological activation of myeloid p38 controls macrophage IL‐12 production and crosstalk to the liver by modulating hepatic FGF21, and subsequently, brown adipose tissue thermogenesis during obesity Abstract Obesity features excessive fat accumulation in several body tissues and induces a state of chronic low‐grade inflammation that contributes to ...
María Crespo +14 more
wiley +1 more source
Journal of Biomedical Science, 2023 Background Cholesterol gallstone disease is a common disease. Reducing cholesterol burden is important to prevent/treat gallstone. In this study, we investigated the application of diosgenin (DG) to prevent the formation of gallstone in mice.
Weiyi Shen +7 more
doaj +1 more source
Cancer Cell International, 2022 Objective N6-methyladenosine (m6A) RNA methylation is involved in governing the mechanism of tumor progression. We aimed to excavate the biological role and mechanism of the m6A methyltransferase METTL3 in cholangiocarcinoma (CCA).
Jingli Cai +6 more
doaj +1 more source
Association between statin use and risk of gallstone disease and cholecystectomy: a meta-analysis of 590,086 patients [PDF]
PeerJ, 2023 Background Statins have been reported to reduce the risk of gallstone disease. However, the impacts of different durations of statin use on gallstone disease have not been clarified.
Yu Chang +4 more
doaj +2 more sources
Translational Oncology, 2023 Introduction: N6-methyladenosine (m6A) is an emerging epigenetic modification, which plays a crucial role in the development of cancer. Nevertheless, the underlying mechanism of m6A-associated proteins and m6A modification in gallbladder cancer remains ...
Jian Qin +7 more
doaj +1 more source