Results 201 to 210 of about 124,755 (303)

The Relationship between Internet Game Addiction and Sense of Meaning in Life of Adolescents: A Latent Profile Analysis. [PDF]

Psychol Res Behav Manag
Ma S, Lu Y, Zhang H, Zhou J, Wang J, Sang Q.   +5 more
europepmc   +1 more source

Effects of resourcefulness on internet game addiction among college students: The mediating role of anxiety and the moderating role of gender. [PDF]

Front Public Health, 2023
Zhang Y, Zhong YL, Luo J, He JL, Lin C, Zauszniewski JA, Zhou JH, Chen Y, Wu CY, Wang SR, Li ZH, Tang J, Li WN, Wu J, Luo JM.   +14 more
europepmc   +1 more source

QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study

Advanced Science, EarlyView.
The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...
María M. Tejero‐Ojeda, Ada Bernaus Vives, Michał Wojciechowski, Dinh Quoc Huy Pham, Mateusz Chwastyk, Mario Vallejo, Anna Novials, Douglas V. Laurents, Mariano Carrión‐Vázquez   +8 more
wiley   +1 more source

Predicting Anxiety and Depression Based on Video Game Addiction with the Mediating Role of Social Support. [PDF]

Actas Esp Psiquiatr
Jahanbakhshi Z, Rezvani N, Pourhasan M, Ahmadi S, Ahmadi SJ.   +4 more
europepmc   +1 more source

Targeting UXS1‐Dependent Glucuronate Detoxification Potentiates Metformin's Anti‐Tumor Efficacy in Lung Adenocarcinoma

Advanced Science, EarlyView.
This study reveals that metformin promotes glucuronic acid metabolism in lung adenocarcinoma by activating UGDH S476 phosphorylation and enhancing the conversion of UDPG to UDPGA based on metabolomics analysis. Through compound virtual screening, it is found that plantainoside targeting UGDH downstream UXS1 leads to UDPGA toxicity accumulation ...
Qihai Sui, Zhencong Chen, Guangyao Shan, Zhengyang Hu, Xing Jin, Jiaqi Liang, Yanjun Yi, Jiacheng Yin, Haochun Shi, Xifei Jiang, Junjie Xi, Zongwu Lin, Cheng Zhan, Fenghao Sun, Wei Jiang   +14 more
wiley   +1 more source

The Relationship Between Smartphone and Game Addiction, Leisure Time Management, and the Enjoyment of Physical Activity: A Comparison of Regression Analysis and Machine Learning Models. [PDF]

Healthcare (Basel)
Namlı S, Çar B, Kurtoğlu A, Yılmaz E, Tekkurşun Demir G, Güvendi B, Batu B, Aldhahi MI.   +7 more
europepmc   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

Explanatory model of behavioral adaptation in video game addiction among adolescents in urban and rural Peru: the mediating role of anxiety. [PDF]

Front Psychol
Huamani-Cahua JC, Ojeda-Flores E, Medina Arce NR, Villanueva Kuong LE, Ojeda-Flores MA.   +4 more
europepmc   +1 more source

AutomataGPT: Transformer‐Based Forecasting and Ruleset Inference for Two‐Dimensional Cellular Automata

Advanced Science, EarlyView.
We introduce AutomataGPT, a generative pretrained transformer (GPT) trained on synthetic spatiotemporal data from 2D cellular automata to learn symbolic rules. Demonstrating strong performance on both forward and inverse tasks, AutomataGPT establishes a scalable, domain‐agnostic framework for interpretable modeling, paving the way for future ...
Jaime A. Berkovich, Noah S. David, Markus J. Buehler   +2 more
wiley   +1 more source

Validation of the Farsi version of the video-game addiction scale for children: its associations with social media addiction, internet addiction and executive functions. [PDF]

BMC Psychol
Rabiei N, Sadeghi S, Ranaei N, Ghanbari N.   +3 more
europepmc   +1 more source