Results 61 to 70 of about 830,866 (349)
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
PENERAPAN LOGIKA FUZZY SUGENO UNTUK PENENTUAN REWARD PADA GAME EDUKASI AKU BISA
JUTI: Jurnal Ilmiah Teknologi Informasi, 2019 This study discusses an application of fuzzy logic in educational game. This game requires a fast player response. We made this game in order to raise children awareness to encounter strangers.
Chaulina Alfianti Oktavia +1 more
doaj +1 more source
Living-into, living-with: A Schutzian account of the player/character relationship [PDF]
, 2016 Games Studies reveals the performative nature of playing a character in a virtual-game-world (Nitsche 2008, p.205; Pearce 2006, p.1; Taylor 2002, p.48). Tbe Player/Character relationship is typically understood in terms of the player’s in-game “presence”
Hardesty, Rebecca A.
core
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
O2O Destination Marketing Using a Location-Based GPS Game:
Maketingu Janaru, 2023 The location-based game “Station Memories!”, in which players travel around more than 9,000 stations throughout Japan with bishôjo (animated beautiful girl) characters, has recently become an online-to-offline (O2O) destination marketing approach for ...
Akinori Ono, Makoto Ono
doaj +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Mind perception and fan fiction: a survey using the IDOLM@STER series
Cogent Social SciencesThis study focuses on the relationship between the impression a character makes on players of a game and the percentage of hetero and homosexualistic fan fiction that uses that character, particularly in the case of femslash works in homosexual ...
Tetsuya Matsui
doaj +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source