Results 51 to 60 of about 1,363,895 (292)

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Synthetic Training Data for Semantic Segmentation of the Environment from UAV Perspective

Aerospace, 2023
Autonomous unmanned aircraft need a good semantic understanding of their surroundings to plan safe routes or to find safe landing sites, for example, by means of a semantic segmentation of an image stream.
Christoph Hinniger, Joachim Rüter
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Perancangan Game First Person Shooter 3D “Zombie Hunter” dengan Menggunakan Metode A*

Journal of Information and Technology, 2017
Video Game adalah sebuah permainan dengan tampilan sebuah gambar atau visual yang dapat memberikan respon balik jika diberikan perintah-perintah tertentu menggunakan alat kontrol pada seperangkat sistem elektronik. Game First Person Shooter (FPS) adalah
Ryan Mahendra Kusuma Putra
doaj  

Integrated Aircraft Engine Energy Management Based on Game Theory

Aerospace
The current generation of integrated power systems is represented by the Adaptive Power and Thermal Management System (APTMS). The coupled performance between the APTMS and the aircraft engine significantly increases the difficulty of energy management ...
Hong Zhang, Chenyang Luo, Xiangping Li, Runcun Li, Zhilong Fan   +4 more
doaj   +1 more source

Motion in Augmented Reality Games: An Engine for Creating Plausible Physical Interactions in Augmented Reality Games

International Journal of Computer Games Technology, 2010
The next generation of Augmented Reality (AR) games will require real and virtual objects to coexist in motion in immersive game environments. This will require the illusion that real and virtual objects interact physically together in a plausible way ...
Brian Mac Namee, David Beaney, Qingqing Dong   +2 more
doaj   +1 more source

Game-Engine-Assisted Research platform for Scientific computing (GEARS) in Virtual Reality

SoftwareX, 2019
The Game-Engine-Assisted Research platform for Scientific computing (GEARS) is a visualization framework developed at the Materials Genome Innovation for Computational Software (MAGICS) center to perform simulations and on-the-fly data exploration in ...
Brandon K. Horton, Rajiv K. Kalia, Erick Moen, Aiichiro Nakano, Ken-ichi Nomura, Michael Qian, Priya Vashishta, Anders Hafreager   +7 more
doaj   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Methods for optimizing the performance of Unity 3D game engine based on third-person perspective game

Journal of Computer Sciences Institute, 2017
Game optimization is one of the most important aspects of their creation. The article describes methods to optimize Unity Engine using third person perspective game as an example.
Krzysztof Siarkowski, Przemysław Sprawka, Małgorzata Plechawska-Wójcik   +2 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source