Results 31 to 40 of about 10,501 (264)
Unifying Rigid and Soft Bodies Representation: The Sulfur Physics Engine
International Journal of Computer Games Technology, 2014 Video games are (also) real-time interactive graphic simulations: hence, providing a convincing physics simulation for each specific game environment is of paramount importance in the process of achieving a satisfying player experience.
Dario Maggiorini +2 more
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Design Foundations for Emotional Game Characters
Eludamos, 2020 Recent Computer Role Playing Games such as Bethesda’s The Elder Scrolls V: Skyrim and Nintendo’s The Legend of Zelda: Breath of the Wild, have entranced us with their expansive, complex worlds.
Geneva Smith, Jacques Carette
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
First Steps in the Use of a Game Engine for Historical Roads and Paths Research
Journal of Computer Applications in Archaeology, 2019 Game engines are developing fast and are used in several scientific disciplines. In the domain of cultural heritage, they have been applied mostly for dynamic visualization.
Willem Vletter
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Game Engine Comparative Anatomy
, 2022 Video game developers use game engines as a tool to manage complex aspects of game development. While engines play a big role in the success of games, to the best of our knowledge, they are often developed in isolation, in a closed-source manner, without architectural discussions, comparison, and collaboration among projects.
Gabriel C. Ullmann +3 more
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
A Novel Camera Control Approach for Planetary-Scale Mapping Utilizing Game Engine Technology
IEEE AccessThree-dimensional geospatial data is the first step in understanding the real world digitally. Realistic city models are used in urban planning and enable various physical simulations.
Ahyun Lee
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
The Investigation on Using Unity3D Game Engine in Urban Design Study
Journal of ICT Research and Applications, 2013 Developing a virtual 3D environment by using game engine is a strategy to incorporate various multimedia data into one platform. The characteristic of game engine that is preinstalled with interactive and navigation tools allows users to explore and ...
Aswin Indraprastha, Michihiko Shinozaki
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