Results 41 to 50 of about 1,363,895 (292)
A Novel Camera Control Approach for Planetary-Scale Mapping Utilizing Game Engine Technology
IEEE AccessThree-dimensional geospatial data is the first step in understanding the real world digitally. Realistic city models are used in urban planning and enable various physical simulations.
Ahyun Lee
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Game Engine Comparative Anatomy
, 2022 Video game developers use game engines as a tool to manage complex aspects of game development. While engines play a big role in the success of games, to the best of our knowledge, they are often developed in isolation, in a closed-source manner, without architectural discussions, comparison, and collaboration among projects.
Gabriel C. Ullmann +3 more
openaire +3 more sources
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
The Investigation on Using Unity3D Game Engine in Urban Design Study
Journal of ICT Research and Applications, 2013 Developing a virtual 3D environment by using game engine is a strategy to incorporate various multimedia data into one platform. The characteristic of game engine that is preinstalled with interactive and navigation tools allows users to explore and ...
Aswin Indraprastha, Michihiko Shinozaki
doaj
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Game Play Schemas: From Player Analysis to Adaptive Game Mechanics
International Journal of Computer Games Technology, 2008 Schema theory provides a foundation for the analysis of game play patterns created by players during their interaction with a game. Schema models derived from the analysis of play provide a rich explanatory framework for the cognitive processes ...
Craig A. Lindley +1 more
doaj +1 more source
Leveraging Unity for 2D Pixel Game Development: Techniques and Best Practices [PDF]
ITM Web of ConferencesThe rapid evolution of game development technologies emphasizes the demand for high-quality graphics and immersive gameplay. Meanwhile, there has also been a pixel art revival in the game development industry.
Wang Ke
doaj +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Virtual Reality and game engines for interactive data visualization and event displays in HEP, an example from the ATLAS experiment [PDF]
EPJ Web of Conferences, 2019 Interactive 3D data visualization plays a key role in HEP experiments, as it is used in many tasks at different levels of the data chain. Outside HEP, for interactive 3D graphics, the game industry makes heavy use of so-called “game engines”, modern ...
Riccardo Maria Bianchi +3 more
doaj +1 more source