Results 51 to 60 of about 891,783 (321)

Optimization on cooperative government and enterprise supplies repertories for maritime emergency: A study case in China

open access: yesAdvances in Mechanical Engineering, 2019
This article studies the location problem of maritime emergency supplies repertories under the joint of government and enterprises, and it proposes the two-stage optimization location model by integrating the location of maritime emergency supplies ...
Yunfei Ai, Qi Zhang
doaj   +1 more source

A Game-Theoretic Framework to Preserve Location Information Privacy in Location-Based Service Applications

open access: yesSensors, 2019
Recently, the growing ubiquity of location-based service (LBS) technology has increased the likelihood of users’ privacy breaches due to the exposure of their real-life information to untrusted third parties.
Mulugeta Kassaw Tefera, Xiaolong Yang
doaj   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Evaluation of the game development process of a location-based mobile game [PDF]

open access: yes, 2014
There is a growing interest of government bodies and NGOs in using (serious) video games in awareness campaigns. Until now, however, little was known on how to set up such a campaign so as to effectively cater to the needs of different stakeholders ...
All, Anissa, Beg, Imran, Van Looy, Jan
core   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

Little Botany: A Mobile Game Utilizing Data Integration to Enhance Plant Science Education

open access: yesInternational Journal of Computer Games Technology, 2017
Mobile devices are rapidly becoming the new medium of educational and social life for young people, and hence mobile educational games have become an important mechanism for learning.
Suphanut Jamonnak, En Cheng
doaj   +1 more source

Location-Based Games For Learning

open access: yes, 2018
Research argues that digital educational games have the potential to make learning more interesting and more effective. However, creating engaging game-based learning experiences remains challenging. To address this challenge, the authors present the game authoring pipeline of the Beaconing Platform that enables the construction of location-based ...
Stanescu, Ioana A.   +6 more
openaire   +2 more sources

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

open access: yesFEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa   +13 more
wiley   +1 more source

The Mesoamerican Ball Game: A Deadly Sport [PDF]

open access: yes, 2018
My presentation is part of the research event “Bridging Cultures in Latin America: Maya and Colonial Heritage in Guatemala and Belize.” This work was conducted during the 2017 Maymester study abroad program in Central America with faculty from UT Austin ...
Cawthon, Rylie
core   +1 more source

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