Results 81 to 90 of about 486,296 (329)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

LPaMI: A Graph-Based Lifestyle Pattern Mining Application Using Personal Image Collections in Smartphones

open access: yesApplied Sciences, 2017
Normally, individuals use smartphones for a variety of purposes like photography, schedule planning, playing games, and so on, apart from benefiting from the core tasks of call-making and short messaging.
Kifayat Ullah Khan   +8 more
doaj   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Use of management games within the education process of future managers at universities in Slovakia and Czech Republic

open access: yesEntrepreneurship and Sustainability Issues
In the current turbulent business environment, the role of management is increasingly demanding, and therefore the demands for future managers in companies are increasing. A decisive role in the preparation of a manager for the performance of his work is
Lucie Lendelova   +4 more
doaj   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

Egocentric fairness perception: emotional reactions and individual differences in overt responses.

open access: yesPLoS ONE, 2014
Extensive research documents the existence of egocentric biases in the perception and application of justice norms. The origin of these biases remains poorly understood.
Benoit Bediou, Klaus R Scherer
doaj   +1 more source

Smoothing Method for Approximate Extensive-Form Perfect Equilibrium

open access: yes, 2017
Nash equilibrium is a popular solution concept for solving imperfect-information games in practice. However, it has a major drawback: it does not preclude suboptimal play in branches of the game tree that are not reached in equilibrium.
Farina, Gabriele   +2 more
core   +1 more source

Cognitive Status in People With Epilepsy in the Republic of Guinea: A Prospective, Case–Control Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with epilepsy (PWE) may experience cognitive deficits but fail to undergo formal evaluation. This study compares cognitive status between PWE and healthy controls in the West African Republic of Guinea. Methods A cross‐sectional, case–control study was conducted in sequential recruitment phases (July 2024–July 2025) at Ignace ...
Maya L. Mastick   +14 more
wiley   +1 more source

The relationships between video game experience and cognitive abilities in adolescents

open access: yesNeuropsychiatric Disease and Treatment, 2019
Mustafa Özçetin,1 Funda Gümüştaş,2 Yakup Çağ,3 İnci Zaim Gökbay,4 Ahu Özmel31Istanbul Faculty of Medicine, Department of Pediatrics, Istanbul University, Istanbul, Turkey; 2Department of Child and Adolescent ...
Özçetin M   +4 more
doaj  

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