Results 31 to 40 of about 7,720 (145)

Identification and analysis of Eimeria nieschulzi gametocyte genes reveal splicing events of gam genes and conserved motifs in the wall-forming proteins within the genus Eimeria (Coccidia, Apicomplexa)

Parasite, 2017
The genus Eimeria (Apicomplexa, Coccidia) provides a wide range of different species with different hosts to study common and variable features within the genus and its species.
Wiedmer Stefanie, Erdbeer Alexander, Volke Beate, Randel Stephanie, Kapplusch Franz, Hanig Sacha, Kurth Michael   +6 more
doaj   +1 more source

Assessment of the transmission blocking activity of antimalarial compounds by membrane feeding assays using natural Plasmodium falciparum gametocyte isolates from West-Africa.

PLoS ONE, 2023
Antimalarial drugs that can block the transmission of Plasmodium gametocytes to mosquito vectors would be highly beneficial for malaria elimination efforts.
Noëlie B Henry, Issiaka Soulama, Samuel S Sermé, Judith M Bolscher, Tonnie T G Huijs, Aboubacar S Coulibaly, Salif Sombié, Nicolas Ouédraogo, Amidou Diarra, Soumanaba Zongo, Wamdaogo M Guelbéogo, Issa Nébié, Sodiomon B Sirima, Alfred B Tiono, Alano Pietro, Katharine A Collins, Koen J Dechering, Teun Bousema   +17 more
doaj   +1 more source

Plasmodium falciparum gametocyte production correlates with genetic markers of parasite replication but is not influenced by experimental exposure to mosquito bitingResearch in context

EBioMedicine
Summary: Background: Plasmodium blood-stage parasites balance asexual multiplication with gametocyte development. Few studies link these dynamics with parasite genetic markers in vivo; even fewer in longitudinally monitored infections.
Sara Lynn Blanken, Aissata Barry, Kjerstin Lanke, Moussa Guelbeogo, Alphonse Ouedraogo, Issiaka Soulama, Sam Aboubacar Coulibaly, Karina Teelen, Wouter Graumans, Elin Dumont, Will Stone, Jordache Ramjith, Matthias Marti, Carolina M. Andrade, Chris Drakeley, Katharine Collins, Alfred Tiono, Teun Bousema   +17 more
doaj   +1 more source

Recognition of Plasmodium falciparum mature gametocyte-infected erythrocytes by antibodies of semi-immune adults and malaria-exposed children from Gabon

Malaria Journal, 2017
Background Transmission of malaria from man to mosquito depends on the presence of gametocytes, the sexual stage of Plasmodium parasites in the infected host.
Tamirat Gebru, Anthony Ajua, Michael Theisen, Meral Esen, Ulysse Ateba Ngoa, Saadou Issifou, Ayola A. Adegnika, Peter G. Kremsner, Benjamin Mordmüller, Jana Held   +9 more
doaj   +1 more source

Persistent Plasmodium falciparum infections enhance transmission-reducing immunity development

Scientific Reports, 2021
Subclinical infections that serve as reservoir populations to drive transmission remain a hurdle to malaria control. Data on infection dynamics in a geographical area is required to strategically design and implement malaria interventions.
Ruth Ayanful-Torgby, Esther Sarpong, Hamza B. Abagna, Dickson Donu, Evans Obboh, Benedicta A. Mensah, Joshua Adjah, Kim C. Williamson, Linda E. Amoah   +8 more
doaj   +1 more source

The Plasmodium falciparum CCCH Zinc Finger Protein ZNF4 Plays an Important Role in Gametocyte Exflagellation through the Regulation of Male Enriched Transcripts

Cells, 2022
CCCH zinc finger proteins (ZFPs) function mainly as RNA-binding proteins (RBPs) and play a central role in the mRNA metabolism. Over twenty seven CCCH-ZFPs are encoded in the genome of the human malaria parasite Plasmodium falciparum, the causative agent
Borja Hanhsen, Afia Farrukh, Gabriele Pradel, Che Julius Ngwa   +3 more
doaj   +1 more source

Plasmodium falciparum Spatial Analysis, Western Kenya Highlands

Emerging Infectious Diseases, 2005
We carried out a population-based study to determine the unbiased, age-specific Plasmodium falciparum prevalence, asexual and sexual parasite density, and spatial distribution to establish rates of infection at a site in western Kenya.
Otsyula G. Munyekenye, Andrew Githeko, Guofa Zhou, Emmanuel Mushinzimana, Noboru Minakawa, Guiyun Yan   +5 more
doaj   +1 more source

Monitoring the density of Plasmodium spp. gametocytes in isolates from patient samples in the region of Porto Velho, Rondônia [PDF]

, 2023
Leandro do Nascimento Martinez, Deyse Conrado Silva, Nairo Brilhante-da-Silva, Francisco Lurdevanhe da Silva Rodrigues, Alzemar Alves de Lima, Mauro Shugiro Tada, Joana D ‘Arc Neves Costa   +6 more
openalex   +1 more source

The WD40-Protein PfWLP1 Ensures Stability of the PfCCp-Based Adhesion Protein Complex in Plasmodium falciparum Gametocytes

Frontiers in Cellular and Infection Microbiology, 2022
Members of the WD40-repeat protein family can be found in all eukaryotic proteomes where they usually serve as interaction platforms for the assembly of large protein complexes and are therefore essential for the integrity of these complexes.
Lena Roling, Ansgar Flammersfeld, Gabriele Pradel, Sandra Bennink   +3 more
doaj   +1 more source

Predominance of asymptomatic and sub-microscopic infections characterizes the Plasmodium gametocyte reservoir in the Peruvian Amazon. [PDF]

PLoS Neglected Tropical Diseases, 2017
Malaria transmission requires that Anopheles mosquitoes ingest Plasmodium gametocyte stages circulating in the human bloodstream. In the context of malaria elimination, understanding the epidemiology of gametocytes relative to all Plasmodium infections ...
Eduard Rovira-Vallbona, Juan José Contreras-Mancilla, Roberson Ramirez, Mitchel Guzmán-Guzmán, Gabriel Carrasco-Escobar, Alejandro Llanos-Cuentas, Joseph M Vinetz, Dionicia Gamboa, Anna Rosanas-Urgell   +8 more
doaj   +1 more source