Results 41 to 50 of about 13,563 (220)

Transmission immunity in malaria: reflections on the underlying immune mechanisms during natural infections and following artificial immunization

Memorias do Instituto Oswaldo Cruz, 1992
Malaria transmission-blocking immunity has been studied in natural malaria infections in man, during infections in animals and following artificial immunization of animals with sexual stage malaria parasites.
Richard Carter, Kamini Mendis
doaj   +1 more source

Anti-Gametocyte Antigen Humoral Immunity and Gametocytemia During Treatment of Uncomplicated Falciparum Malaria: A Multi-National Study

Frontiers in Cellular and Infection Microbiology, 2022
IntroductionUnderstanding the human immune response to Plasmodium falciparum gametocytes and its association with gametocytemia is essential for understanding the transmission of malaria as well as progressing transmission blocking vaccine candidates ...
Katherine O’Flaherty, Jo-Anne Chan, Jo-Anne Chan, Jo-Anne Chan, Julia C. Cutts, Julia C. Cutts, Sophie G. Zaloumis, Elizabeth A. Ashley, Elizabeth A. Ashley, Aung Pyae Phyo, Damien R. Drew, Arjen M. Dondorp, Arjen M. Dondorp, Nicholas P. Day, Nicholas P. Day, Mehul Dhorda, Mehul Dhorda, Mehul Dhorda, Rick M. Fairhurst, Pharath Lim, Chanaki Amaratunga, Sasithon Pukrittayakamee, Tran Tinh Hien, Tran Tinh Hien, Ye Htut, Mayfong Mayxay, Mayfong Mayxay, Mayfong Mayxay, M. Abul Faiz, Olugbenga A. Mokuolu, Marie A. Onyamboko, Caterina Fanello, Caterina Fanello, Caterina Fanello, Eizo Takashima, Takafumi Tsuboi, Michael Theisen, Michael Theisen, Francois Nosten, Francois Nosten, Francois Nosten, James G. Beeson, James G. Beeson, James G. Beeson, James G. Beeson, Julie A. Simpson, Nicholas J. White, Nicholas J. White, Freya J. I. Fowkes, Freya J. I. Fowkes, Freya J. I. Fowkes   +50 more
doaj   +1 more source

Development of reverse-transcription PCR techniques to analyse the density and sex ratio of gametocytes in genetically diverse Plasmodium chabaudi infections [PDF]

, 2007
We have developed cross-genotype and genotype-specific quantitative reverse-transcription PCR (qRT-PCR) assays to detect and quantify the number of parasites, transmission stages (gametocytes) and male gametocytes in blood stage Plasmodium chabaudi ...
Abdel-Wahab, Alano, Babiker, Bell, Cheeseman, Damien R. Drew, De Roode, De Roode, De Roode, Dye, Ferguson, Ferguson, Foster, Gardner, Gautret, Hamilton, Khan, Mackinnon, Nee, Paterson, Paul, Paul, Paul, Pinheiro, Ranford-Cartwright, Read, Read, Read, Reece, Reece, Reece, Sarah E. Reece, Schall, Schall, Schneider, Shutler, Sinden, Taylor, Taylor, Wargo, Wargo, West, West, West, West   +44 more
core   +1 more source

Molecular evidence of incipient speciation within Anopheles gambiae s.s. in West Africa [PDF]

, 2001
We karyotyped and identified by polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) analysis Anopheles gambiae s.s. samples collected in several African countries. The data show the existence of two non-panmictic molecular forms,
Akogbeto, M, Coluzzi, M, della Torre, A, Dossou-Yovo, J, Fanello, C, Favia, G, Petrarca, V   +6 more
core   +1 more source

Erythrocyte Membrane Makeover by Plasmodium falciparum Gametocytes [PDF]

Frontiers in Microbiology, 2019
Plasmodium falciparum sexual parasites, called gametocytes, are the only parasite stages responsible for transmission from humans to Anopheles mosquitoes. During their maturation, P. falciparum gametocytes remodel the structural and mechanical properties of the membrane of their erythrocyte host.
Gaëlle Neveu, Gaëlle Neveu, Catherine Lavazec, Catherine Lavazec   +3 more
openaire   +4 more sources

Changes in metabolic phenotypes of Plasmodium falciparum in vitro cultures during gametocyte development. [PDF]

, 2014
BACKGROUND: Gametocytes are the Plasmodium life stage that is solely responsible for malaria transmission. Despite their important role in perpetuating malaria, gametocyte differentiation and development is poorly understood.
Delves, MJ, Lamour, SD, Saric, J, Straschil, U   +3 more
core   +3 more sources

Concentration of Plasmodium falciparum gametocytes in whole blood samples by magnetic cell sorting enhances parasite infection rates in mosquito feeding assays

Malaria Journal, 2017
Background Mosquito-feeding assays are important tools to guide the development and support the evaluation of transmission-blocking interventions. These functional bioassays measure the sporogonic development of gametocytes in blood-fed mosquitoes ...
Isaie J. Reuling, Will J. R. Stone, Marga van de Vegte-Bolmer, Geert-Jan van Gemert, Rianne Siebelink-Stoter, Wouter Graumans, Kjerstin Lanke, Teun Bousema, Robert W. Sauerwein   +8 more
doaj   +1 more source

Identification and analysis of Eimeria nieschulzi gametocyte genes reveal splicing events of gam genes and conserved motifs in the wall-forming proteins within the genus Eimeria (Coccidia, Apicomplexa)

Parasite, 2017
The genus Eimeria (Apicomplexa, Coccidia) provides a wide range of different species with different hosts to study common and variable features within the genus and its species.
Wiedmer Stefanie, Erdbeer Alexander, Volke Beate, Randel Stephanie, Kapplusch Franz, Hanig Sacha, Kurth Michael   +6 more
doaj   +1 more source

Mode of action and choice of antimalarial drugs for intermittent preventive treatment in infants.

, 2009
Intermittent preventive treatment in infants (IPTi) is an effective and safe malaria control strategy. However, it remains unclear what antimalarials should be used to replace sulfadoxine-pyrimethamine (SP) when and where SP is no longer an effective ...
Cairns, Matthew, Gosling, Roly, Gesase, Samwel, Mosha, Jacklin, Greenwood, Brian, Chandramohan, Daniel   +5 more
core   +1 more source

Ultrastructure and function of mitochondria in gametocytic stage of Plasmodium falciparum

Parasite, 2000
Morphological properties of the mitochondrial organelles in the asexual and sexual gametocytic stages of Plasmodium falciparum have been analyzed and found to be markedly different.
Krungkrai J., Prapunwattana P., Krungkrai S.R.   +2 more
doaj   +1 more source