Results 31 to 40 of about 13,563 (220)

Predicting the likelihood and intensity of mosquito infection from sex specific Plasmodium falciparum gametocyte density

open access: yeseLife, 2018
Understanding the importance of gametocyte density on human-to-mosquito transmission is of immediate relevance to malaria control. Previous work (Churcher et al., 2013) indicated a complex relationship between gametocyte density and mosquito infection ...
John Bradley   +22 more
doaj   +1 more source

Rosette formation by Plasmodium vivax gametocytes favors the infection in Anopheles aquasalis

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
Plasmodium vivax is a public health problem and the most common type of malaria outside sub-Saharan Africa. The capacity of cytoadhesion, rosetting, and liver latent phase development could impact treatment and disease control. Although the ability to P.
Luis Carlos Salazar Alvarez   +33 more
doaj   +1 more source

Detection of Plasmodium falciparum male and female gametocytes and determination of parasite sex ratio in human endemic populations by novel, cheap and robust RTqPCR assays [PDF]

open access: yes, 2017
The presence of Plasmodium falciparum gametocytes in peripheral blood is essential for human to mosquito parasite transmission. The detection of submicroscopic infections with gametocytes and the estimation of the gametocyte sex ratio are crucial to ...
Alano, Pietro   +8 more
core   +2 more sources

Biology of Plasmodium falciparum gametocyte sex ratio and implications in malaria parasite transmission

open access: yesMalaria Journal, 2019
While significant advances have been made in understanding Plasmodium falciparum gametocyte biology and its relationship with malaria parasite transmission, the gametocyte sex ratio contribution to this process still remains a relevant research question.
Noëlie Béré Henry   +9 more
doaj   +1 more source

Pleiotropic Roles for the Plasmodium berghei RNA Binding Protein UIS12 in Transmission and Oocyst Maturation

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Colonization of the mosquito host by Plasmodium parasites is achieved by sexually differentiated gametocytes. Gametocytogenesis, gamete formation and fertilization are tightly regulated processes, and translational repression is a major regulatory ...
Katja Müller   +5 more
doaj   +1 more source

Demographical, hematological and serological risk factors for Plasmodium falciparum gametocyte carriage in a high stable transmission zone in Cameroon.

open access: yesPLoS ONE, 2019
Presence of mature gametocyte forms of malaria parasites in peripheral blood is a key requirement for malaria transmission. Yet, studies conducted in most malaria transmission zones report the absence of gametocyte in the majority of patients.
Estelle Essangui   +13 more
doaj   +1 more source

Low Levels of Human Antibodies to Gametocyte-Infected Erythrocytes Contrasts the PfEMP1-Dominant Response to Asexual Stages in P. falciparum Malaria

open access: yesFrontiers in Immunology, 2019
Vaccines that target Plasmodium falciparum gametocytes have the potential to reduce malaria transmission and are thus attractive targets for malaria control. However, very little is known about human immune responses to gametocytes present in human hosts.
Jo-Anne Chan   +12 more
doaj   +1 more source

Quantifying Reductions in Plasmodium falciparum Infectivity to Mosquitos: A Sample Size Calculator to Inform Clinical Trials on Transmission-Reducing Interventions

open access: yesFrontiers in Immunology, 2022
Malaria transmission depends on the presence of mature Plasmodium transmission stages (gametocytes) that may render blood-feeding Anopheles mosquitos infectious.
Jordache Ramjith   +7 more
doaj   +1 more source

Plasticity in transmission strategies of the malaria parasite, Plasmodium chabaudi : environmental and genetic effects [PDF]

open access: yes, 2012
Parasites may alter their behaviour to cope with changes in the within-host environment. In particular, investment in transmission may alter in response to the availability of parasite resources or host immune responses.
Cameron, Angus   +4 more
core   +1 more source

Revisiting gametocyte biology in malaria parasites [PDF]

open access: yesFEMS Microbiology Reviews, 2019
ABSTRACT Gametocytes are the only form of the malaria parasite that is transmissible to the mosquito vector. They are present at low levels in blood circulation and significant knowledge gaps exist in their biology. Recent reductions in the global malaria burden have brought the possibility of elimination and eradication, with renewed ...
Ngotho, Priscilla   +5 more
openaire   +2 more sources

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