Results 111 to 120 of about 18,519 (218)
DNA-encoded nucleosome occupancy is associated with transcription levels in the human malaria parasite Plasmodium falciparum. [PDF]
BackgroundIn eukaryotic organisms, packaging of DNA into nucleosomes controls gene expression by regulating access of the promoter to transcription factors.
Bunnik, Evelien M +6 more
core +3 more sources
Comparative 3D ultrastructure of Plasmodium falciparum gametocytes
AbstractDespite the enormous significance of malaria parasites for global health, some basic features of their ultrastructure remain obscure. Here, we apply high-resolution volumetric electron microscopy to examine and compare the ultrastructure of the transmissible male and female sexual blood stages of Plasmodium falciparum as well as the more ...
Felix Evers +8 more
openaire +5 more sources
Plasmodium falciparum gametocytes: their longevity and infectivity
The longevity and infectivity of isolated populations of Plasmodium falciparum gametocytes were studied. Following chloroquine treatment gametocyte numbers fell with a constant rate of loss over a period of 16–24days; the populations had a half-life of 2·4 days. The sex ratio stayed constant throughout at 4 female:1 male.
M E, Smalley, R E, Sinden
openaire +2 more sources
In August 1983 the Authors studied 36 patients with Plasmodium falciparum malaria and 14 normal individuals born in Humaita region who had never had malaria, had no spleen enlargement and had negative parasitemia as well as passive hemagglutination ...
Domingos Alves Meira +6 more
doaj +1 more source
Gametocytes, sporozoites and liver schizonts.
Plasmodium falciparum differs from other human species of Plasmodium in the short, limited exo-erythrocytic stage in the life cycle, which is an apparent disadvantage in surviving through a prolonged non-transmission season such as occurs throughout much of tropical Africa.
openaire +3 more sources
The Gates Malaria Partnership: a consortium approach to malaria research and capacity development.
Recently, there has been a major increase in financial support for malaria control. Most of these funds have, appropriately, been spent on the tools needed for effective prevention and treatment of malaria such as insecticide-treated bed nets, indoor ...
Bhasin, Amit +2 more
core +1 more source
Dynamics of P. Falciparum Gametocytemia in Symptomatic Patients in an Area of Intense Perennial Transmission in Tanzania. [PDF]
We investigated the dynamics of Plasmodium falciparum gametocytemia in symptomatic patients attending a local dispensary in the Kilombero district, Tanzania.
Akim, N I +5 more
core
Los gametocitos de Plasmodium son los responsables de la transmisión del huésped vertebrado al mosquito vector. Sufren un proceso de desarrollo complejo a partir de parásitos asexuales, que no está completamente entendido, expresando proteínas y ...
Carla Contreras-Ochoa, Janine M Ramsey
doaj
BackgroundPrimaquine (PQ) is the only currently licensed antimalarial that prevents Plasmodium vivax (Pv) relapses. It also clears mature P. falciparum (Pf) gametocytes, thereby reducing post-treatment transmission. Randomized PQ treatment in a treatment-
Rahel Wampfler +9 more
doaj +1 more source
A reiterative method for calculating the early bactericidal activity of antituberculosis drugs.
Studies of early bactericidal activity (EBA) are important in the rapid evaluation of new antituberculosis drugs. Historically, these have concentrated on the log fall in the viable count in sputum during the first 48 hours of therapy.
Charalambous, Bambos M +2 more
core +1 more source

