Results 111 to 120 of about 18,519 (218)

DNA-encoded nucleosome occupancy is associated with transcription levels in the human malaria parasite Plasmodium falciparum. [PDF]

open access: yes, 2014
BackgroundIn eukaryotic organisms, packaging of DNA into nucleosomes controls gene expression by regulating access of the promoter to transcription factors.
Bunnik, Evelien M   +6 more
core   +3 more sources

Comparative 3D ultrastructure of Plasmodium falciparum gametocytes

open access: yesNature Communications
AbstractDespite the enormous significance of malaria parasites for global health, some basic features of their ultrastructure remain obscure. Here, we apply high-resolution volumetric electron microscopy to examine and compare the ultrastructure of the transmissible male and female sexual blood stages of Plasmodium falciparum as well as the more ...
Felix Evers   +8 more
openaire   +5 more sources

Plasmodium falciparum gametocytes: their longevity and infectivity

open access: yesParasitology, 1977
The longevity and infectivity of isolated populations of Plasmodium falciparum gametocytes were studied. Following chloroquine treatment gametocyte numbers fell with a constant rate of loss over a period of 16–24days; the populations had a half-life of 2·4 days. The sex ratio stayed constant throughout at 4 female:1 male.
M E, Smalley, R E, Sinden
openaire   +2 more sources

Malaria at Humaita county, Amazonas state, Brazil: XVII — immune response in patients with Plasmodium falciparum according to gametocytes

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 1985
In August 1983 the Authors studied 36 patients with Plasmodium falciparum malaria and 14 normal individuals born in Humaita region who had never had malaria, had no spleen enlargement and had negative parasitemia as well as passive hemagglutination ...
Domingos Alves Meira   +6 more
doaj   +1 more source

Gametocytes, sporozoites and liver schizonts.

open access: yesSouth African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1974
Plasmodium falciparum differs from other human species of Plasmodium in the short, limited exo-erythrocytic stage in the life cycle, which is an apparent disadvantage in surviving through a prolonged non-transmission season such as occurs throughout much of tropical Africa.
openaire   +3 more sources

The Gates Malaria Partnership: a consortium approach to malaria research and capacity development.

open access: yes, 2012
Recently, there has been a major increase in financial support for malaria control. Most of these funds have, appropriately, been spent on the tools needed for effective prevention and treatment of malaria such as insecticide-treated bed nets, indoor ...
Bhasin, Amit   +2 more
core   +1 more source

Dynamics of P. Falciparum Gametocytemia in Symptomatic Patients in an Area of Intense Perennial Transmission in Tanzania. [PDF]

open access: yes
We investigated the dynamics of Plasmodium falciparum gametocytemia in symptomatic patients attending a local dispensary in the Kilombero district, Tanzania.
Akim, N I   +5 more
core  

Gametocitos de Plasmodium vivax y Plasmodium falciparum: etapas relegadas en el desarrollo de vacunas Plasmodium vivax and Plasmodium falciparum gametocyte stages are neglected in vaccine development

open access: yesSalud Pública de México, 2004
Los gametocitos de Plasmodium son los responsables de la transmisión del huésped vertebrado al mosquito vector. Sufren un proceso de desarrollo complejo a partir de parásitos asexuales, que no está completamente entendido, expresando proteínas y ...
Carla Contreras-Ochoa, Janine M Ramsey
doaj  

Effects of liver-stage clearance by Primaquine on gametocyte carriage of Plasmodium vivax and P. falciparum.

open access: yesPLoS Neglected Tropical Diseases, 2017
BackgroundPrimaquine (PQ) is the only currently licensed antimalarial that prevents Plasmodium vivax (Pv) relapses. It also clears mature P. falciparum (Pf) gametocytes, thereby reducing post-treatment transmission. Randomized PQ treatment in a treatment-
Rahel Wampfler   +9 more
doaj   +1 more source

A reiterative method for calculating the early bactericidal activity of antituberculosis drugs.

open access: yes, 2002
Studies of early bactericidal activity (EBA) are important in the rapid evaluation of new antituberculosis drugs. Historically, these have concentrated on the log fall in the viable count in sputum during the first 48 hours of therapy.
Charalambous, Bambos M   +2 more
core   +1 more source

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