Results 121 to 130 of about 331,897 (280)

CircTspan3 Promotes Cartilage Development Through ANNEXIN A2‐Mediated Ferroptosis and Apoptosis Inhibition and Exosome‐Mediated Paracrine Signaling

open access: yesAdvanced Science, EarlyView.
This study reveals that XBP1s drives production of circTspan3, a circular RNA that strengthens cartilage by boosting anabolic activity and limiting cell death. Phosphorylated ANXA2 directs circTspan3 into exosomes, enabling paracrine repair. Exosomal circTspan3 expands growth‐plate cartilage and promotes in vivo regeneration, highlighting its promise ...
Yiming Pan   +16 more
wiley   +1 more source

Gender differences in internet gaming among university students: a discriminant analysis

open access: yesFrontiers in Psychology
IntroductionResearch on gaming and gaming habits has predominantly focused on younger populations, particularly males. The main objective of this study was to analyze gender-based differences in gamer profiles, considering variables related to gaming ...
Júlia Gisbert-Pérez   +6 more
doaj   +1 more source

Light Therapy Alleviates Addiction‐Related Symptoms and Reshapes Habenula and Midbrain Pathways

open access: yesAdvanced Science, EarlyView.
This study investigates light therapy for treating Internet Gaming Disorder (IGD). Functional MRI (fMRI) data reveal that light therapy enhances brain connectivity, particularly between the habenula and the medial orbitofrontal cortex (mOFC). These changes are associated with reduced withdrawal symptoms and addiction severity, highlighting the ...
Jinhui Li   +10 more
wiley   +1 more source

Stigma and other public perceptions of recreational gaming and gaming disorder: A large-scale qualitative analysis

open access: yesComputers in Human Behavior Reports
Introduction: Individuals affected by addictive disorders commonly report stigma, which reduces engagement in treatment. To better understand the nature of stigma associated with gaming disorder, a new addictive disorder in the ICD-11, this study ...
Christina R. Galanis, Daniel L. King
doaj   +1 more source

Centralised gaming models: providing optimal gambling behaviour controls [PDF]

open access: yes, 2009
The expansion in the gaming industry and its widening attraction points to the need for ever more verifiable means of controlling problem gambling. Various strategies have been built into casino venue operations to address this, but recently, following a
Griffiths, MD, Wood, RTA
core  

DLP 4D Printing of Programmable Molecularly‐Engineered Liquid Crystal Elastomer Actuators

open access: yesAdvanced Science, EarlyView.
We introduce an original and versatile approach for printing liquid crystal elastomers that exhibit reversible shape morphing using digital light processing. 3D‐tructures are printed in a partially cured state, mechanically programmed, and then fully crosslinked to fix molecular alignment.
Rakine Mouhoubi   +2 more
wiley   +1 more source

Macrophage TRIM21 Inhibition Ameliorates Murine Acute Pancreatitis via PHB2‐Mediated Mitochondrial Stabilization

open access: yesAdvanced Science, EarlyView.
Macrophage‐derived TRIM21 drives the progression of AP via ubiquitin‐proteasome‐mediated degradation of PHB2, leading to impaired PHB2‐mediated mitophagy. Therefore, accumulation of cytosolic mtDNA hyperactivates the cGAS‐STING signaling axis, thereby amplifying inflammatory cascades.
Yansong Xu   +7 more
wiley   +1 more source

Federal Law, State Policy, and Indian Gaming

open access: yes, 2004
This Article will set forth the legal authorization and the economic success of Indian gaming by asking and answering two rhetorical questions: What makes Indian gaming lawful? and What makes Indian gaming successful?
Washburn, Kevin K.
core  

Adolescent Internet gambling: what do we actually know? [PDF]

open access: yes, 2010
To date, little research has been done on the relationship between adolescent children and online gambling, especially regarding the conditions in which they can access e-gaming sites or the regularity with which they play.
Griffiths, MD, Parke, J
core  

Visualizing and Quantifying Impact with Mechanochromic Sensing Paints Based on Self‐Assembled Polydiacetylene‐Silk Core‐Shell Vesicles

open access: yesAdvanced Science, EarlyView.
Tracking physical impacts is important in many fields. Self‐assembled microparticles made from polydiacetylene and silk fibroin that change color from blue to red when hit can provide an alternative approach to traditional mechanical transducers, quantitatively visualizing impact with responses ranging from <100 to 770 N.
Marco Lo Presti   +4 more
wiley   +1 more source

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