Gamma-aminobutyric acid mediates nicotine biosynthesis in tobacco under flooding stress
Gamma-aminobutyric acid (GABA) is a four-carbon non-protein amino acid conserved from bacteria to plants and vertebrates. Increasing evidence supports a regulatory role for GABA in plant development and the plant's response to environmental stress.
Xiaoming Zhang+4 more
doaj +1 more source
The general anaesthetic etomidate inhibits the excitability of mouse thalamocortical relay neurons by modulating multiple modes of GABAA receptor-mediated inhibition [PDF]
Modulation of thalamocortical (TC) relay neuron function has been implicated in the sedative and hypnotic effects of general anaesthetics. Inhibition of TC neurons is mediated predominantly by a combination of phasic and tonic inhibition, together with a
Alkire+57 more
core +2 more sources
The Factors of the Classification of Protein Amino Acids [PDF]
In this work it is shown that three pairs of the factors appear to be the key, i.e. main factors of a natural classification of protein (canonical) amino acids within the amino acid (genetic) code. First pair: the factors of the habit of an amino acid molecule (size and polarity).
arxiv
GABAergic modulation of beta power enhances motor adaptation in frontotemporal lobar degeneration
Abstract INTRODUCTION We examined how abnormal prefrontal neurophysiology and changes in gamma‐aminobutyric acid‐ergic (GABAergic) neurotransmission contribute to behavioral impairments in disorders associated with frontotemporal lobar degeneration (FTLD). METHODS We recorded magnetoencephalography during an adaptive visuomotor task from 11 people with
Laura E. Hughes+11 more
wiley +1 more source
Insights into GABA receptor signalling in TM3 Leydig cells [PDF]
gamma-Aminobutyric acid (GABA) is an emerging signalling molecule in endocrine organs, since it is produced by endocrine cells and acts via GABA(A) receptors in a paracrine/autocrine fashion.
Artur Mayerhofer+28 more
core +2 more sources
This work proposes a comprehensive two‐dimensional gas chromatography method for the resolution and quantification of 27 amino acids, including 17 enantiomeric pairs, as stable N‐trifluoroacetyl‐O‐methyl ester derivatives. The derivatization approach in combination with enantioselective two‐dimensional gas chromatography has proven to be highly ...
Raphaël Pepino+4 more
wiley +1 more source
Lack of evidence for central sensitization in idiopathic, non-traumatic neck pain : a systematic review [PDF]
Background: Chronic neck pain is a common problem with a poorly understood pathophysiology. Often no underlying structural pathology can be found and radiological imaging findings are more related to age than to a patient's symptoms.
Bramer, Wichor+9 more
core +1 more source
Modeling of the formation of short-chain acids in propane flames [PDF]
In order to better understand their potential formation in combustion systems, a detailed kinetic mechanism for the formation of short-chain monocarboxylic acids, formic (HCOOH), acetic (CH3COOH), propionic (C2H5COOH) and propenic (C2H3COOH)) acids, has been developed. Simulations of lean (equivalence ratios from 0.9 to 0.48) laminar premixed flames of
arxiv
Discovery Of Copper Catalyst For New Chemical Polishing Acid On Superconducting Niobium [PDF]
High field Q-slope (HFQS) seriously limits the high gradient performance of the buffered chemically polished (BCP) superconducting radio frequency (SRF) niobium cavities. The direct cause or mechanism is not yet fully understood. In our recent extensive data analysis, we concluded that the potential root cause could be nitrogen contamination on the ...
arxiv
A thermodynamic basis for prebiotic amino acid synthesis and the nature of the first genetic code [PDF]
Of the twenty amino acids used in proteins, ten were formed in Miller's atmospheric discharge experiments. The two other major proposed sources of prebiotic amino acid synthesis include formation in hydrothermal vents and delivery to Earth via meteorites.
arxiv +1 more source