Results 91 to 100 of about 110,079 (354)

Could the Biological Potency of Porcelia macrocarpa R.E. Fries (Annonaceae) be Linked to Its Diverse Metabolite Profile?

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Porcelia macrocarpa is a Brazilian plant species belonging to the Annonaceae family. To date, more than 190 compounds have been identified and/or isolated from this species, with terpenoids comprising the majority (62%). Alkaloids represent the second most abundant class (11%), followed by steroids (4%), acetogenins (4%), fatty acids (4 ...
Fernanda Thevenard   +4 more
wiley   +1 more source

INHIBITORY NEUROTRANSMITTERS AND THEIR INFLUENCE ON TUMOR IN PATIENTS WITH GLIOMAS

open access: yesСибирский онкологический журнал, 2016
The review deals with the problem of activity of gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter, in gliomas. It has been shown that GABA has an antitumor activity in most models and cancer patients have an increased level of GABA ...
A. V. Kartashev, V. B. Voitenkov
doaj  

Negative modulation of the GABAAρ1 receptor function by l-cysteine [PDF]

open access: yes, 2017
l-Cysteine is an endogenous sulfur-containing amino acid with multiple and varied roles in the central nervous system, including neuroprotection and the maintenance of the redox balance.
Beltrán González, Andrea Natalia   +2 more
core   +1 more source

Rubrolides A, D, P, T, U: Total Syntheses and Antibacterial Evaluation of Highly Brominated Marine Natural Products

open access: yesChemistryEurope, EarlyView.
Following the Danube Flow. The first total syntheses of highly brominated rubrolides T, U, and U‐analog, together with the efficient and divergent syntheses of rubrolides A, D, and P. The dibrominated key intermediate, obtained via a Suzuki‐Miyaura cross‐coupling reaction, is the centerpiece of the synthesis.
Jasmin Janneschütz   +7 more
wiley   +1 more source

Detection of acetylcholinesterase activity and gamma-aminobutyric acid binding sites in Dicrocoelium dendriticum

open access: yesParasite, 2000
In the present study we report the presence of acetylcholinesterase activity and gamma-aminobutyric acid binding sites in crude extracts of Dicrocoelium dendriticum. This indirectly demonstrates the presence of acetylcholine and GABA.
Giménez-Pardo C.   +3 more
doaj   +1 more source

Influence of GABA and GABA-producing Lactobacillus brevis DPC 6108 on the development of diabetes in a streptozotocin rat model [PDF]

open access: yes, 2016
peer-reviewedThe aim of this study was to investigate if dietary administration of γ-aminobutyric acid (GABA)-producing Lactobacillus brevis DPC 6108 and pure GABA exert protective effects against the development of diabetes in streptozotocin (STZ ...
Cotter, Paul D.   +9 more
core   +1 more source

Advances in Parahydrogen‐Induced Polarization for Nuclear Magnetic Resonance of Peptides, Proteins, and Biopolymers

open access: yesChemistryEurope, EarlyView.
Hyperpolarization by parahydrogen‐induced polarization enhances the sensitivity of nuclear magnetic resonance spectroscopy of amino acids, peptides, mini‐proteins, and biopolymers using nonnatural amino acids with unsaturated side chains up to three orders of magnitude.
Gerd Buntkowsky
wiley   +1 more source

Effect of Curcumin on the Hypothalamus Levels of the Potent Inhibitory Neurotransmitter ,Gamma aminobutyric acid

open access: yesResearch in Molecular Medicine, 2015
Background: There are some reports in the literature showing that hypothalamus synthesizes and secretes amino acid neurotransmitters. According to several studies, elevated serum levels of gamma-amino butyric acid (GABA), a potent inhibitory ...
Shokoufe Nikpour Moghaddam   +3 more
doaj  

Enhancement of Antioxidant Activity and Bioactive Compounds in Soy Whey Fermented with Lactiplantibacillus plantarum and Weissella confusa [PDF]

open access: yesمجله پژوهش‌های علوم و صنایع غذایی ایران
Soy whey (SW) is a byproduct from tofu and soy protein isolate (SPI) production that contains various nutrients such as protein, amino acids, minerals, carbohydrates, isoflavones.
Shadi Atashgahi   +4 more
doaj   +1 more source

Coordination of opposing sex-specific and core muscle groups regulates male tail posture during Caenorhabditis elegans male mating behavior [PDF]

open access: yes, 2009
Background To survive and reproduce, animals must be able to modify their motor behavior in response to changes in the environment. We studied a complex behavior of Caenorhabditis elegans, male mating behavior, which provided a model for understanding ...
A Barrios   +45 more
core   +4 more sources

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