Results 71 to 80 of about 66,550 (299)
Cervical dystonia: a disorder of the midbrain network for covert attentional orienting.
Frontiers in Neurology, 2014 While the pathogenesis of cervical dystonia remains unknown, recent animal and clinical experimental studies have indicated its probable mechanisms. Abnormal temporal discrimination is a mediational endophenotype of cervical dystonia and informs new ...
Michael eHutchinson +18 more
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Epilepsia, EarlyView.Abstract Objective Sigma‐1 is a chaperone protein that serves as a key homeostatic regulator, implicated in neuronal excitability and seizure control. Positive allosteric modulators offer a use‐dependent means to enhance Sigma‐1 activity, potentially with favorable tolerability compared to direct agonists.
Eva‐Lotta von Rüden +5 more
wiley +1 more source
Insilico Analysis of γ- Aminobutaric Acid Transaminase (GABA-T) of Brassica napus (Rape)
Journal of Advanced Biotechnology and Experimental Therapeutics, 2019 γ-Aminobutyric acid (GABA) is a very important metabolite which plays a crucial role in signal transmission, stress metabolism and some other activities are also reported. Although the actual role of GABA shunt is not clearly understood. Three key
Md. Shahjahan, Shahidur Rahman
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WONOEP XVII appraisal: The role of the extracellular matrix in epilepsy
Epilepsia, EarlyView.Abstract The extracellular matrix (ECM) is composed of proteoglycans and glycoproteins that regulate the external environment surrounding neurons, glia, and the vascular system. The ECM is vital for maintaining the structure and function of the brain and also acts as a reservoir for various signaling molecules and neurotransmitters, modulating synaptic
Eleonora Lugara +7 more
wiley +1 more source
Epilepsia, EarlyView.Abstract Objective We investigated the presence and potential functional relevance of antimitochondrial autoantibodies in patients suspicious for autoimmune encephalitis (AIE) associated with psychiatric symptoms and/or seizures, who were negative for known antineuronal autoantibodies.
Annika Breuer +12 more
wiley +1 more source
INHIBITORY NEUROTRANSMITTERS AND THEIR INFLUENCE ON TUMOR IN PATIENTS WITH GLIOMAS
Сибирский онкологический журнал, 2016 The review deals with the problem of activity of gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter, in gliomas. It has been shown that GABA has an antitumor activity in most models and cancer patients have an increased level of GABA ...
A. V. Kartashev, V. B. Voitenkov
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Frontiers in Cellular Neuroscience, 2018 Parvalbumin- (PV-) containing basket cells constitute perisomatic GABAergic inhibitory interneurons innervating principal cells at perisomatic area, a strategic location that allows them to efficiently control the output and synchronize oscillatory ...
Marita G. Hansen +4 more
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Corticocortical evoked potential amplitude is altered by cortical stimulation in epilepsy
Epilepsia, EarlyView.Abstract Objective Neurostimulation is an established therapy for drug‐resistant epilepsy, but optimizing stimulation parameters remains a major challenge. Corticocortical evoked potential (CCEP) amplitude may serve as an immediate biomarker of neurostimulation effects, enabling rapid parameter optimization.
Bethany J. Stieve +4 more
wiley +1 more source
Epilepsia, EarlyView.Abstract Epilepsy affects more than 50 million individuals globally and has a substantial genetic component that remains to be completely understood. Traditional studies have focused on severe, early onset cases enrolled through clinical or research settings.
Jessica Castrillon Lal +5 more
wiley +1 more source
Research in Molecular Medicine, 2015 Background: There are some reports in the literature showing that hypothalamus synthesizes and secretes amino acid neurotransmitters. According to several studies, elevated serum levels of gamma-amino butyric acid (GABA), a potent inhibitory ...
Shokoufe Nikpour Moghaddam +3 more
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