Results 71 to 80 of about 69,874 (309)
Epilepsia, EarlyView.On day 0 adult male and female rats were injected with Stable Substance P‐Saporin (SSP‐SAP) at 4 unilateral sites along the longitudinal axis of the dentate gyrus. Rats exhibited spontaneous electrographic and behavioral reactive seizures between days 4‐6. There was a progressive loss of CA1 and CA3 neurons and a progressive increase in astrocytes over
Srijal Gupta +4 more
wiley +1 more source
Effects of Lycopene and Sodium Valproate on Pentylenetetrazol-Induced Kindling in Mice
Iranian Journal of Medical Sciences, 2016 Sodium valproate and tomato extract have been studied in different experimental models of epilepsy individually. The aim of the present study was to evaluate the effect of lycopene on the antiepileptic effects of sodium valproate against ...
Vinay Kumar +3 more
doaj
Molecular Pain, 2018 Background Neuropathic pain is observed in patients as chemotherapeutic oxaliplatin is used to treat metastatic digestive tumors; however, the mechanisms responsible for hyperalgesia are not well understood.
Dongsheng Xu +5 more
doaj +1 more source
Cervical dystonia: a disorder of the midbrain network for covert attentional orienting.
Frontiers in Neurology, 2014 While the pathogenesis of cervical dystonia remains unknown, recent animal and clinical experimental studies have indicated its probable mechanisms. Abnormal temporal discrimination is a mediational endophenotype of cervical dystonia and informs new ...
Michael eHutchinson +18 more
doaj +1 more source
Synergistic effects of gamma-aminobutyric acid and melatonin on seed germination and cadmium tolerance in tomato [PDF]
, 2023 Yiying Lv +8 more
openalex +1 more source
Paroxysmal slow waves mark ictal networks
Epilepsia, EarlyView.Abstract Objective Epilepsy diagnosis and treatment monitoring are hindered by the episodic, heterogeneous expression of seizures and by normal‐appearing scalp electroencephalography (EEG) in many patients. We previously described paroxysmal slow‐wave events (PSWEs), brief epochs of broadband slowing detectable on EEG in people with epilepsy.
Florent J. M. Boyer‐Aymé +13 more
wiley +1 more source
Insilico Analysis of γ- Aminobutaric Acid Transaminase (GABA-T) of Brassica napus (Rape)
Journal of Advanced Biotechnology and Experimental Therapeutics, 2019 γ-Aminobutyric acid (GABA) is a very important metabolite which plays a crucial role in signal transmission, stress metabolism and some other activities are also reported. Although the actual role of GABA shunt is not clearly understood. Three key
Md. Shahjahan, Shahidur Rahman
doaj +1 more source
Epilepsia, EarlyView.Abstract Heterozygous loss‐of‐function variants in the gene SCN1A, which encodes the voltage‐gated sodium channel (VGSC) pore‐forming (α) subunit NaV1.1, lead to a spectrum of neurological disease, including Dravet syndrome. NaV1.1 is prominently expressed at the proximal portion of the axon initial segment (AIS) of fast‐spiking γ‐aminobutyric ...
Ania K. Dabrowski +4 more
wiley +1 more source
Frontiers in Cellular Neuroscience, 2018 Parvalbumin- (PV-) containing basket cells constitute perisomatic GABAergic inhibitory interneurons innervating principal cells at perisomatic area, a strategic location that allows them to efficiently control the output and synchronize oscillatory ...
Marita G. Hansen +4 more
doaj +1 more source
Epilepsia, EarlyView.Abstract Objective Ketogenic dietary therapies can reduce seizure frequency in drug‐resistant epilepsy, but adherence to the classical ketogenic diet is often poor. Intermittent fasting supplemented with medium‐chain triglycerides (MCTs) may offer a more feasible and less restrictive alternative.
Wiebke Hahn +11 more
wiley +1 more source