Results 101 to 110 of about 66,533 (308)

White Matter Dysfunction and Neurotransmitter Basis Underlying the Freezing of Gait in Parkinson's Disease

iNew Medicine, EarlyView.
In the freezing of gait in Parkinson's disease, white matter shows decreased local activity but increased functional connectivity. These distinct dysfunctions are uniquely associated with specific neurotransmitter systems (GABA, dopamine, etc.), mapping a new neurochemical basis for this debilitating symptom. ABSTRACT Freezing of gait (FOG) is a severe
Pingping Liu, Jinmei Sun, Lili Hu, Xin Chen, Jinying Han, Liuzhenxiong Yu, Siyu Fan, Rong Ye, Kai Wang, Gong‐Jun Ji, Panpan Hu   +10 more
wiley   +1 more source

Subunit composition of glutamate and gamma-aminobutyric acid receptors in status epilepticus

, 2014
Tobias Loddenkemper, Delia M. Talos, Ryan T. Cleary, Annelise Joseph, Iván Sánchez Fernández, Andreas V. Alexopoulos, Prakash Kotagal, Imad Najm, Frances E. Jensen   +8 more
openalex   +2 more sources

Chronic Low‐Dose Unsymmetrical Dimethylhydrazine Exposure in Rats: Multiorgan Mechanisms and Biomarker Identification

Journal of Applied Toxicology, EarlyView.
ABSTRACT Unsymmetrical dimethylhydrazine (UDMH), a highly toxic rocket propellant with known multiorgan effects, requires urgent characterization of its chronic low‐dose toxicity. Using an integrated approach including exploratory transcriptomics (n = 3/group) and metabolomic (n = 4/group) approaches in male Sprague–Dawley rats exposed to high‐dose ...
Fuzhou Liu, Bing Liu, Keli Wang, Xiaoyu Wang, Zhen Sun, Xiaojuan Pan, Zengming Zhao   +6 more
wiley   +1 more source

Altered γ-aminobutyric acid neurotransmission in major depressive disorder: a critical review of the supporting evidence and the influence of serotonergic antidepressants

Drug Design, Development and Therapy, 2015
Alan L Pehrson, Connie Sanchez External Sourcing and Scientific Excellence, Lundbeck Research USA, Paramus, NJ, USA Abstract: Evidence suggesting that central nervous system γ-aminobutyric acid (GABA) concentrations are reduced in patients with ...
Pehrson AL, Sanchez C
doaj  

Association between the gut microbiome and neurodevelopmental outcomes in infants with congenital heart disease: A prospective cohort study

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background Children with congenital heart disease are at risk for poor neurodevelopment. The gut microbiome may influence neurodevelopmental outcomes through the gut‐brain axis. This study investigated the association of early‐life gut microbiome with neurodevelopmental outcomes.
Michael P. Fundora, Lily Dressner, Christina Calamaro, Ann‐Marie Brown, Amelia St. John, Rachael Keiffer, Nneka Alexander, Hui Huang, Scott Gillespie, Patricia Wei Denning, Kolby Sanders‐Lewis, Jinbing Bai   +11 more
wiley   +1 more source

A plasmid-borne gadRCB operon contributes to acid tolerance in Lactiplantibacillus plantarum ZR79

Applied Microbiology and Biotechnology
The glutamate decarboxylase (GAD) system catalyzed the conversion of L-glutamate to gamma-aminobutyric acid (GABA) in a proton-consuming reaction, which played a critical role to maintain intracellular pH homeostasis.
Chengfei Fan, Zeyu Cao, Xinfeng Liu, Yan Hao, Zhengyuan Zhai, Yanling Hao   +5 more
doaj   +1 more source

Hyposensitivity to Gamma-Aminobutyric Acid in the Ventral Tegmental Area During Alcohol Withdrawal: Reversal by Histone Deacetylase Inhibitors [PDF]

, 2013
Devinder Arora, Sudarat Nimitvilai, Tara Teppen, Maureen A. McElvain, Amul J. Sakharkar, Chang You, Subhash C. Pandey, Mark S. Brodie   +7 more
openalex   +1 more source

Alterations in brain metabolites in rats with experimental periodontitis: A metabolomic approach

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis (PD) is a chronic inflammatory disease with systemic effects. Emerging evidence suggests a link between periodontal inflammation and neurological changes, but the biochemical mechanisms in key brain regions, such as the hippocampus and amygdala, remain unclear.
Ramona Ramalho de Souza Pereira, Caíque Olegário Diniz e Magalhães, Elizabeth Luciana Marinho Miguel, Larissa Vieira Toledo, Débora Ribeiro Orlando, Alan Rodrigues Teixeira Machado, Bruno Del Bianco Borges, Luciano José Pereira, Marco Fabrício Dias‐Peixoto, Eric Francelino Andrade   +9 more
wiley   +1 more source

Development of Starter Cultures for Precision Fermentation of Kombucha with Enriched Gamma-Aminobutyric Acid (GABA) Content [PDF]

Geun-Hyung Kim, Kwang-Rim Baek, Ga-Eun Lee, Jihyun Lee, Ji-Hyun Moon, Seung‐Oh Seo   +5 more
openalex   +1 more source

Desensitization of Gamma Aminobutyric Acid (GABA) Receptors in Muscle Fibers of the Crab Cancer borealis [PDF]

, 1970
René Epstein, Harry Grundfest
openalex   +1 more source