Results 191 to 200 of about 110,079 (354)

Effects of Intravenous Ketamine on Posttraumatic Stress Disorder (PTSD): A Systematic Review

open access: yesActa Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Posttraumatic stress disorder (PTSD) is a mental disorder resulting from exposure to traumatic events. Evidence suggests that ketamine may be efficacious in treating PTSD, however, ketamine's mechanisms in treating PTSD remain unclear. Herein, this review aims to evaluate the clinical outcomes of ketamine treatment in persons with
Liyang Yin   +15 more
wiley   +1 more source

Astrocytic gamma-aminobutyric acid dysregulation as a therapeutic target for posttraumatic stress disorder. [PDF]

open access: yesSignal Transduct Target Ther
Yoon S   +18 more
europepmc   +1 more source

Electrophysiological sexual dimorphism as an early risk marker of alcohol use in adolescence: A longitudinal neuroimaging study

open access: yesAddiction, EarlyView.
Abstract Aims To identify the brain activity profiles associated with alcohol consumption and to address its causes. Furthermore, we sought to examine the relationship between these electrophysiological markers and the excitation–inhibition balance, as well as to explore the potential moderating role of sex in these associations.
Alberto del Cerro‐León   +9 more
wiley   +1 more source

Alterations in Gut Microbiota and Metabolism in Cirrhotic Portal Hypertension: Implications for Disease Progression

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
In‐depth multiomics analyses revealed that the gut microbiota in patients with CPH is dysbiotic. Altered gut microbiota plays an important role in the progression of CPH and affects the host's arginine metabolism to promote arginine biosynthesis. The pro‐inflammatory effects of certain gut bacteria induce iNOS expression, which together act on the ...
Qun Zhang   +15 more
wiley   +1 more source

Neurotransmitter signaling in white matter [PDF]

open access: yes, 2014
Butt, Arthur M.   +2 more
core   +1 more source

Gamma-aminobutyric acid aggravates nephrotoxicity induced by cisplatin in female rats [PDF]

open access: bronze, 2016
Elham Peysepar   +4 more
openalex   +1 more source

Calponin‐3 is associated with epilepsy through the regulation of astrocyte activity

open access: yesBrain Pathology, EarlyView.
Increased calponin‐3 expression correlates with astrocyte activation in epileptic mice, modulating adenosine metabolism regulators ADK and ENT1. Calponin‐3 overexpression increased susceptibility to epileptic seizures, while its downregulation reduces spontaneous recurrent seizures, identifying it as a potential therapeutic target for epilepsy ...
Lu Chen   +12 more
wiley   +1 more source

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