Results 171 to 180 of about 66,550 (299)

Dexmedetomidine promotes colorectal cancer progression mediated by gamma-aminobutyric acid signaling. [PDF]

Cancer Metab
Dong J, Wu Y, Che J, He Z, Zhang J.
europepmc   +1 more source

Gold‐standard evidence and best practice guidance for menstrual cycle‐informed clinical care: An overview for clinicians

British Journal of Clinical Psychology, EarlyView.
Abstract Objectives To synthesize current evidence and provide clinically actionable recommendations for integrating menstrual cycle‐related processes—particularly hormone sensitivity, Premenstrual Dysphoric Disorder (PMDD) and Premenstrual Exacerbation (PME)—into psychological assessment, formulation and treatment.
Ellen R. Lambert, Louise N. Nolan, Katja M. Schmalenberger   +2 more
wiley   +1 more source

Perfluorooctanesulfonic acid (PFOS) antagonizes gamma-aminobutyric acid (GABA) receptors in larval zebrafish and mammalian models. [PDF]

Toxicol Sci
Owen R, de Macedo G, Nerlich J, Scharkin I, Bartmann K, Döbler J, Engelmann B, Rolle-Kampczyk UE, Leuthold D, Gutsfeld S, Schweiger N, Tal T.   +11 more
europepmc   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Fluorine-18 Radiolabeled Single-Chain Antibody Variable Fragment 1F4 Targets α1-Subunit Gamma-Aminobutyric Acid Type A Receptors in Mice. [PDF]

J Med Chem
García de Lucas Á, Samani NA, Moisio O, Kovacs L, Savela R, Soini SL, Oksanen S, Helin JS, Rajander J, Airaksinen AJ, Lamminmäki U, López-Picón F.   +11 more
europepmc   +1 more source

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

British Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman, Christopher J. Black, Andrea Shin, Daniel Keszthelyi   +3 more
wiley   +1 more source

Construction of a co-reaction system for ethanol-promoted gamma-aminobutyric acid synthesis by Pediococcus pentosaceus. [PDF]

Amino Acids
Yang SY, Li YJ, Hong WC.
europepmc   +1 more source

Benzodiazepines and the Gamma-aminobutyric Acid (GABA) Receptor

The Kurume Medical Journal, 1981
HIGASHI, HIDEHO, INOKUCHI, HIROE, NISHI, SYOGORO, INANAGA, KAZUTOYO   +3 more
openaire   +3 more sources

GIP in Cardiovascular and Kidney Disease: From Physiology to Pharmacology

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To provide a comprehensive overview of the cardiovascular and renal effects of glucose‐dependent insulinotropic polypeptide (GIP) by integrating its physiological role with recent human trial data on tirzepatide, the first dual GIP and glucagon‐like peptide‐1 (GLP‐1) receptor agonist.
Michelantonio De Fano, Line L. Haurum, Christine R. Schwarz, Francesca Porcellati, Andreas Andersen   +4 more
wiley   +1 more source

gamma-Aminobutyric acid in brain: its formation from glutamic acid.

Journal of Biological Chemistry, 1950
E. Roberts, S. Frankel
semanticscholar   +1 more source