Results 151 to 160 of about 108,344 (304)

Effect of Water Suppression and Metabolite Cycling on Quantification of 1H MRS Spectra in the Human Brain at 3 Tesla

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose This study investigates the effect of VAPOR water suppression and metabolite cycling on metabolite quantification and macromolecules in proton magnetic resonance spectroscopy. Methods Single‐voxel semi‐LASER spectra (TR/TE = 3000/28 ms) and metabolite‐nulled spectra (macromolecules) were acquired in five healthy subjects in the ...
Dinesh K. Deelchand, Pierre‐Gilles Henry   +1 more
wiley   +1 more source

A Longitudinal Assessment of Anterior Cingulate Cortex Gamma-aminobutyric Acid in Antipsychotic Medication-naïve First Episode Psychosis Patients. [PDF]

Schizophr Bull
Samson GD, Maximo JO, Nelson EA, Kraguljac NV, Armstrong WP, Benningfield B, Adnani SN, Bashir A, Lahti AC.   +8 more
europepmc   +1 more source

The Impact and Reliability of Tissue Segmentation on In Vivo Magnetic Resonance Spectroscopy Metabolite Quantification

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Quantification of metabolite concentrations using MRS requires tissue‐dependent signal corrections. Accurate estimation of voxel tissue composition is therefore essential. Commonly used brain tissue segmentation tools differ in their algorithms and implementation, potentially introducing variability in MRS‐derived concentration ...
Jessica Archibald, Kay Chioma Igwe, Antonia Kaiser, Karl Landheer, Jaimie Lee, John L. K. Kramer, Aaron T. Gudmundson, Helge J. Zöllner, Georg Oeltzschner, Candace C. Fleischer, Niklaus Zölch, Jamie Near, Mark Mikkelsen   +12 more
wiley   +1 more source

Repeated oral administration of gamma-aminobutyric acid (GABA) does not cause reproductive or developmental toxicity in rats. [PDF]

Toxicol Rep
Li X, Kulkarni A, Yamada H, Yamashita Y, Kim YI.   +4 more
europepmc   +1 more source

The Effect of Remimazolam Administration on Emergence Delirium in Children After General Anesthesia: A Systematic Review With Meta‐Analysis of Randomized Controlled Trials

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Emergence delirium commonly occurs in pediatric patients after general anesthesia, causing distress and potential harm. Remimazolam, an ultra‐short‐acting benzodiazepine, has recently been introduced in pediatric anesthesia, but its preventive role against emergence delirium remains unclear.
Ji‐Na Kim, Hyo‐Seok Na, Hyun‐Jung Shin   +2 more
wiley   +1 more source

Gamma-aminobutyric acid transaminase mediates tumor suppression in renal cell carcinoma through the cGAS-STING-interferon-β axis. [PDF]

Sci Rep
Feng Y, Cao S, Cai T, Lu Y, Jiang B, Lv Z, Tang J, Gao F, Zhao X, Liu C, Wang Q, Feng J, Wang Z, Ai Q, Cheng Q, Fan W, Li H.   +16 more
europepmc   +1 more source

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

Pediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu, Boqing Xu, Chunfang Dai, Yayan Pang, Zhifang Dong   +4 more
wiley   +1 more source

Synergistic role of gamma-aminobutyric acid and melatonin in mitigating lead stress in rice. [PDF]

BMC Plant Biol
Wang X, Chen C, Sun X, Zaman QU, Wang C, Tang H.   +5 more
europepmc   +1 more source

Gamma-aminobutyric acid

Scholarpedia, 2007
openaire   +1 more source

Proteomic Profiling of Primary Hippocampal Neurons Reveals Noncanonical GFAP Expression and Metabolic Adaptations in Glia‐Free Culture

PROTEOMICS, EarlyView.
ABSTRACT Despite their widespread use as a research model, a comprehensive, quantitative proteomic profile of the cultured hippocampal neurons has remained unexplored. Here, we provide the first global proteomic characterization of primary murine hippocampal neurons cultured for 14 days under near‐physiological glucose conditions (2.5 mM).
Dominika Drulis‐Fajdasz, Kinga Gostomska‐Pampuch, Natalia Pudełko‐Malik, Mariusz Fleszar, Agnieszka Gizak, Jacek R. Wiśniewski, Dariusz Rakus   +6 more
wiley   +1 more source