Results 231 to 240 of about 94,242 (328)

Comparison of Remimazolam and Propofol for Sedation in Endoscopic Retrograde Cholangiopancreatography: A Systematic Review and Meta‐Analysis With Trial Sequential Analysis

open access: yesDigestive Endoscopy, EarlyView.
This systematic review and meta‐analysis of 5 randomized controlled trials (n = 965) compares the safety profile of remimazolam versus propofol for sedation during ERCP. Remimazolam was associated with a significantly lower incidence of hypoxia, hypotension, and bradycardia.
In Jung Kim   +3 more
wiley   +1 more source

Preferential superficial cortical layer activation during seizure propagation

open access: yesEpilepsia, Volume 66, Issue 3, Page 929-941, March 2025.
Abstract Objective Focal cortical seizures travel long distances from the onset zone, but the long‐distance propagation pathways are uncertain. In vitro and in vivo imaging techniques have investigated the local spread of seizures but did not elucidate long‐distance spread. Furthermore, classical studies in slices suggested seizure spread locally along
Anastasia Brodovskaya   +4 more
wiley   +1 more source

Fast activity chirp patterns in focal seizures from patients and animal models

open access: yesEpilepsia, Volume 66, Issue 3, Page 621-631, March 2025.
Abstract Time–frequency analysis of focal seizure electroencephalographic signals performed with depth electrodes in human temporal lobe structures has revealed the occurrence at onset of oscillations at approximately 30–100 Hz that feature a monotonic rapid decay in frequency content.
Maxime Lévesque   +6 more
wiley   +1 more source

EEG signal dimension is an index of seizure propensity and antiseizure medication effects in a mouse model of acquired epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Variability in the frequency, timing, and pattern of seizures may influence the assessment of the effect of antiseizure medications (ASMs) when measuring seizure frequency, especially in patients with infrequent seizures. A low seizure rate is an exclusion criterion for enrollment of patients with epilepsy in clinical trials and ...
Massimo Rizzi   +4 more
wiley   +1 more source

Synaptic inhibitory dynamics drive benzodiazepine response in pediatric status epilepticus

open access: yesEpilepsia, EarlyView.
Abstract Objective Pediatric status epilepticus (SE) is a medical emergency associated with significant morbidity. Benzodiazepines (BZPs) are the current first‐line treatment, but do not work in more than one third of children presenting with SE. Animal studies have shown that SE can cause changes in synaptic inhibition signaling that can ultimately ...
Tommaso Fedele   +5 more
wiley   +1 more source

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