ABSTRACT Unsymmetrical dimethylhydrazine (UDMH), a highly toxic rocket propellant with known multiorgan effects, requires urgent characterization of its chronic low‐dose toxicity. Using an integrated approach including exploratory transcriptomics (n = 3/group) and metabolomic (n = 4/group) approaches in male Sprague–Dawley rats exposed to high‐dose ...
Fuzhou Liu +6 more
wiley +1 more source
A Proton Magnetic Resonance Spectroscopy (1H MRS) Pilot Study Revealing Altered Glutamatergic and Gamma-Aminobutyric Acid (GABA)ergic Neurotransmission in Social Anxiety Disorder (SAD). [PDF]
Elsaid S +4 more
europepmc +1 more source
Ivermectin Toxicity in Humans and Animals: Clinical Spectrum, Mechanisms, and Management
ABSTRACT Ivermectin is a widely used macrocyclic lactone with established efficacy against a broad range of parasitic infections in humans and animals and a long‐standing reputation for clinical safety. However, increasing evidence indicates that ivermectin can produce clinically relevant toxicity under specific conditions, particularly involving the ...
Serkan Yilmaz +3 more
wiley +1 more source
Effects of Pretreatment Methods on Gamma-Aminobutyric Acid Enrichment and Quality Improvement in Highland Barley Beverages. [PDF]
Yin X +5 more
europepmc +1 more source
ABSTRACT Mung bean (Vigna radiata (L.) Wilczek) is emerging as a valuable ingredient in modern food systems due to its nutritional benefits, functional versatility, and alignment with plant‐based, clean‐label, and sustainable food trends. This review highlights recent technological advancements in mung bean processing, covering primary processing steps
Suresh Sakhare +4 more
wiley +1 more source
Gamma -aminobutyric acid ameliorates neurological impairments in type 1 diabetes mellitus mice by regulating the "gut flora-LPS-TLR4-NF-ΚB" signalling Axis. [PDF]
Wang J, Zhang L, Wang X, Dong J, Li J.
europepmc +1 more source
The Dual Role of Autophagy in Cancer: Mechanisms and Therapeutic Strategies
Autophagy is a conserved cellular process degrading dysfunctional organelles and protein aggregates to maintain cell homeostasis, and it exhibits context‐dependent duality in cancer. Autophagy functions as a critical tumor‐suppressive mechanism by preventing DNA damage and mutation during tumor initiation.
Xiang‐Zheng Gao +4 more
wiley +1 more source
A simple and effective method to enhance the level of gamma-aminobutyric acid in Chinese yam tubers while preserving its original appearance. [PDF]
Wang Q +12 more
europepmc +1 more source
ABSTRACT Purpose Using artificial intelligence neural networks to generate a representation that maps the input directly to neurochemical concentrations and metabolite‐level average transverse relaxation times (T2). Methods The proposed model used time‐domain JPRESS data as input and was trained to be invariant to phase shifts, frequency offsets, and ...
Yan Zhang, Jun Shen
wiley +1 more source
Gamma-aminobutyric acid for delaying type 1 diabetes mellitus: an update. [PDF]
Sutedja JC, Liyis BG, Saraswati MR.
europepmc +1 more source

