Negative modulation of the GABAAρ1 receptor function by l-cysteine [PDF]
l-Cysteine is an endogenous sulfur-containing amino acid with multiple and varied roles in the central nervous system, including neuroprotection and the maintenance of the redox balance.
Beltrán González, Andrea Natalia+2 more
core +1 more source
A systematic review of Gamma-aminobutyric Acid Receptor Type B autoimmunity.
OBJECTIVE To review the available research to describe the clinical characteristics and neoplastic associations of patients with gamma-aminobutyric acid receptor type B (GABAB-R) autoantibodies.
Jake H. McKay+2 more
semanticscholar +1 more source
Coordination of opposing sex-specific and core muscle groups regulates male tail posture during Caenorhabditis elegans male mating behavior [PDF]
Background To survive and reproduce, animals must be able to modify their motor behavior in response to changes in the environment. We studied a complex behavior of Caenorhabditis elegans, male mating behavior, which provided a model for understanding ...
A Barrios+45 more
core +4 more sources
Gamma-aminobutyric acid as a potential postbiotic mediator in the gut–brain axis
Gamma-aminobutyric acid (GABA) plays a crucial role in the central nervous system as an inhibitory neurotransmitter. Imbalances of this neurotransmitter are associated with neurological diseases, such as Alzheimer’s and Parkinson’s disease, and ...
Jason D. Braga+2 more
semanticscholar +1 more source
GABA-enhanced collective behavior in neuronal axons underlies persistent gamma-frequency oscillations [PDF]
Gamma (30–80 Hz) oscillations occur in mammalian electroencephalogram in a manner that indicates cognitive relevance. In vitro models of gamma oscillations demonstrate two forms of oscillation: one occurring transiently and driven by discrete afferent ...
A. Bibbig+25 more
core +2 more sources
Calcium Imaging Reveals Coordinated Simple Spike Pauses in Populations of Cerebellar Purkinje Cells
The brain’s control of movement is thought to involve coordinated activity between cerebellar Purkinje cells. The results reported here demonstrate that somatic Ca2+ imaging is a faithful reporter of Na+-dependent “simple spike” pauses and enables us to ...
Jorge E. Ramirez, Brandon M. Stell
doaj +1 more source
Effects of ethylenediamine – a putative GABA-releasing agent – on rat hippocampal slices and neocortical activity in vivo [PDF]
The simple diamine diaminoethane (ethylenediamine, EDA) has been shown to activate GABA receptors in the central and peripheral nervous systems, partly by a direct action and partly by releasing endogenous GABA.
Addae, J.I., Lui, C., Stone, T.W.
core +1 more source
Genetically altered AMPA-type glutamate receptor kinetics in interneurons disrupt long-range synchrony of gamma oscillation [PDF]
Gamma oscillations synchronized between distant neuronal populations may be critical for binding together brain regions devoted to common processing tasks.
A. Bibbig+51 more
core +3 more sources
Background: Different proposed mechanisms for insulin resistance have been put forth to understand the relationship and changes in insulin resistance. Looking at the levels of insulin, the neurotransmitter gamma-aminobutyric acid, glucose transport type
Ismael Sadeq Khashan+1 more
doaj +1 more source
Genetic Factor in Etiology of Febrile Seizures
Investigators from Istanbul, Turkey, studied R43Q mutations of the gamma-aminobutyric acid A receptor (GABRG2) gene, located on the long arm of chromosome 5, in 44 children with febrile seizure (FS) and 49 without.
J Gordon Millichap, John J Millichap
doaj +1 more source