Results 291 to 300 of about 182,849 (338)
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Nature Reviews Clinical Oncology, 2009
Peripheral T-cell lymphomas (TCLs) are uncommon neoplasms, accounting for about 12% of all lymphoid tumors worldwide. TCLs in which gammadelta T-cell receptors are expressed (gammadelta TCLs) are extremely aggressive and rare (
TRIPODO, Claudio +6 more
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Peripheral T-cell lymphomas (TCLs) are uncommon neoplasms, accounting for about 12% of all lymphoid tumors worldwide. TCLs in which gammadelta T-cell receptors are expressed (gammadelta TCLs) are extremely aggressive and rare (
TRIPODO, Claudio +6 more
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Clinical and Applied Immunology Reviews, 2003
Abstract Protection from exogenous invaders and elimination of endogenous aberrations are the main contributions of T cells to homeostasis. T cells with Vγ9Vδ2-encoded T-cell receptors (TCRs) have a unique ability to interact with a plethora of phosphoantigens in a major histocompatibility complex (MHC)-unrestricted manner. The biological function of
Miroslav Malkovsky +8 more
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Abstract Protection from exogenous invaders and elimination of endogenous aberrations are the main contributions of T cells to homeostasis. T cells with Vγ9Vδ2-encoded T-cell receptors (TCRs) have a unique ability to interact with a plethora of phosphoantigens in a major histocompatibility complex (MHC)-unrestricted manner. The biological function of
Miroslav Malkovsky +8 more
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Hepatosplenic gamma-delta T-cell lymphoma
Critical Reviews in Oncology/Hematology, 2012Hepatosplenic T-cell lymphoma (HSTL) is a rare and aggressive extranodal lymphoma derived mostly from cytotoxic γδ T-cells. The peak incidence is in adolescents and young adults, and is more common in males. Up to 20% of HSTL arise in the setting of chronic immune suppression, most commonly solid organ transplantation or prolonged antigenic stimulation.
Ferreri AJ, Govi S, PILERI, STEFANO
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Gamma Delta T Cell Function in Ruminants
Veterinary Clinics of North America: Food Animal Practice, 2019Gamma delta (γδ) T cells constitute a major lymphocyte population in peripheral blood and epithelial surfaces. They play nonredundant roles in host defense against diverse pathogens. Although γδ T cells share functional features with other cells of the immune system, their distinct methods of antigen recognition, rapid response, and tissue tropism make
Mariana, Guerra-Maupome +2 more
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Peptide antigens for gamma/delta T cells
Cellular and Molecular Life Sciences, 2011γδ T cells express adaptive antigen receptors encoded by rearranging genes. Their diversity is highest in the small region of TCR V-J junctions, especially in the δ chain, which should enable the γδ TCRs to distinguish differences in small epitopes.
Willi K, Born +7 more
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2001
T cell receptor and function cosegregate in gamma-delta T Cell subsets, R.L. O'Brien, M. Lahn, W.K. Born, et al role of the IL-7 receptor in gamma-delta T cell development, K. Ikuta, H.-C. Lee, S.-K. Ye epidermal and dermal gamma-delta T cells, K. Tamaki, M. Sugaya, Y.
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T cell receptor and function cosegregate in gamma-delta T Cell subsets, R.L. O'Brien, M. Lahn, W.K. Born, et al role of the IL-7 receptor in gamma-delta T cell development, K. Ikuta, H.-C. Lee, S.-K. Ye epidermal and dermal gamma-delta T cells, K. Tamaki, M. Sugaya, Y.
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Human T cell receptor gamma delta + T cells.
Seminars in immunology, 1991TCR gamma delta + T cells represent a minority of CD3+ T cells in many species including man. The molecular structure of the TCR gamma and delta loci in man is well understood. The gamma and delta loci contain V, D, J and C gene segments. These segments do not rearrange randomly but in a coordinated, ordered fashion during thymic development. Therefore,
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Cutaneous gamma–delta T-cell lymphoma
Leukemia & Lymphoma, 2008Cutaneous gamma–delta T-cell lymphoma (CGD-TCL) is a rare entity that has been included as a provisional category in the newly revised World Health Organisation–European Organisation for Research a...
A. Amado +4 more
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Lifespan of gamma/delta T cells.
The Journal of experimental medicine, 1998Information on the turnover and lifespan of murine gamma/delta cells was obtained by administering the DNA precursor, bromodeoxyuridine (BrdU), in the drinking water and staining lymphoid cells for BrdU incorporation. For TCR-gamma/delta (Vgamma2) transgenic mice, nearly all gamma/delta thymocytes became BrdU+ within 2 d and were released rapidly into ...
D F, Tough, J, Sprent
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