Protein-Glutamine Gamma-Glutamyltransferase [PDF]
, 2016 Transglutaminases (TGs) are a family of enzymes (EC 2.3.2.13) that catalyze the formation of amide bonds between proteins to form insoluble cross-linked protein aggregates that are resistant to chemicals, detergents, and proteases degradation (Griffin et al. 2002; Yokoyama et al. 2004). TG activity was first observed in 1957 by Clarke et al.
Martins, Ivone, Choupina, Altino
openaire +6 more sources
Circulating gamma‐glutamyltransferase fractions in cirrhosis [PDF]
Liver International, 2014 AbstractBackground & AimsFour gamma‐gultamyltransferases (GGT) fractions (b‐, m‐, s‐, and f‐GGT) have been identified in human plasma and their concentrations and ratios vary in different pathological conditions. To assess the behaviour of fractional GGT in cirrhotic patients evaluated for liver transplantation.MethodsThis was a single‐centre ...
Hassan A. Elawdi +8 more
openaire +6 more sources
Redox Mechanisms in Cisplatin Resistance of Cancer Cells: The Twofold Role of Gamma-Glutamyltransferase 1 (GGT1). [PDF]
Front Oncol, 2022 Pompella A, Corti A, Visvikis A.
europepmc +3 more sources
Link between persistent, unexplained gamma-glutamyltransferase elevation and porto-sinusoidal vascular disorder. [PDF]
JHEP RepPugliese N +15 more
europepmc +3 more sources
Gamma glutamyltransferase and risk of future dementia in middle‐aged to older Finnish men: A new prospective cohort study [PDF]
, 2016 Introduction: We assessed the association of gamma glutamyltransferase (GGT) with risk of dementia. Methods Serum GGT activity was assessed at baseline in the Kuopio Ischemic Heart Disease prospective cohort of 2415 relatively healthy men with good ...
Setor K. Kunutsor, Jari A. Laukkanen
openalex +6 more sources
Gamma-glutamyltransferases: exploring the complexity of a multi-functional family of enzymes. [PDF]
Frontiers in Pharmacology, 2014 Maria eFranzini +3 more
doaj +2 more sources
Cumulative Exposure to High γ-Glutamyl Transferase Level and Risk of Diabetes: A Nationwide Population-Based Study [PDF]
Endocrinology and Metabolism, 2022 Background Elevated γ-glutamyl transferase (γ-GTP) level is associated with metabolic syndrome, impaired glucose tolerance, and insulin resistance, which are risk factors for type 2 diabetes. We aimed to investigate the association of cumulative exposure
Ji-Yeon Park +6 more
doaj +1 more source
Unequal Effects of Myosin 5B Mutations in Liver and Intestine Determine the Clinical Presentation of Low-Gamma-Glutamyltransferase Cholestasis. [PDF]
Hepatology, 2020 van IJzendoorn SCD +4 more
europepmc +3 more sources
Baseline and long-term gamma-glutamyltransferase, heart failure and cardiac arrhythmias in middle-aged Finnish men: Prospective study and pooled analysis of published evidence [PDF]
, 2016 AIM: To assess the associations of baseline and long-term gamma-glutamyltransferase (GGT) activity with risk of heart failure (HF), ventricular arrhythmias (VAs) and atrial fibrillation (AF).METHODS: GGT measurements were made in a prospective cohort of ...
Setor K. Kunutsor +4 more
openalex +5 more sources
Hepatology, EarlyView., 2022 NRPT 1X reduces ALT and ceramide 14:0 in 65% of subjects as compared to only 28% in the placebo group. Abstract Background and Aims The prevalence of NAFLD is increasing globally and on a path to becoming the most frequent cause of chronic liver disease. Strategies for the prevention and treatment of NAFLD are urgently needed.
Ryan W. Dellinger +7 more
wiley +1 more source