Results 31 to 40 of about 200,887 (335)

Expression of the inhibitory Ly49E receptor is not critically involved in the immune response against cutaneous, pulmonary or liver tumours [PDF]

, 2016
Natural killer (NK) lymphocytes are part of the innate immune system and are important in immune protection against tumourigenesis. NK cells display a broad repertoire of activating and inhibitory cell surface receptors that regulate NK cell activity ...
Filtjens, Jessica, Keirsse, Jiri, Kerre, Tessa, Leclercq, Georges, Plum, Jean, Taghon, Tom, Taveirne, Sylvie, Van Acker, Aline, Van Ammel, Els, Van Ginderachter, Jo A, Vandekerckhove, Bart   +10 more
core   +2 more sources

The influence of zoledronate and teriparatide on gamma delta T cells in mice

Journal of Dental Sciences, 2017
Background/purpose: Few studies have investigated the possibility that bisphosphonate-related osteonecrosis of the jaw (BRONJ) might reflect an immune response; however, gamma delta T cells have been shown to significantly decline in the blood of BRONJ ...
Eiki Yamachika, Yuichi Matsui, Masakazu Matsubara, Tatsushi Matsumura, Naoki Nakata, Norifumi Moritani, Atsushi Ikeda, Hidetsugu Tsujigiwa, Naoya Ohara, Seiji Iida   +9 more
doaj   +1 more source

Synthesis of analogues of (E)-1-hydroxy-2-methylbut-2-enyl 4-diphosphate, an isoprenoid precursor and human γδ T cell activator [PDF]

, 2008
(E)-1-Hydroxy-2-methyl-but-2-enyl 4-diphosphate (HMBPP) is an intermediate in the non-mevalonate pathway for the biosynthesis of isoprenoids and also serves as a very strong activator of human gamma delta T cells expressing V gamma 9V delta 2 receptors ...
Jomaa, Hassan, Lacey, Carl Jeffrey, Röhrich, Rene C, Van Calenbergh, Serge, Van Hoof, Steven, Wiesner, Jochen   +5 more
core   +2 more sources

The making of multivalent gamma delta TCR anti-CD3 bispecific T cell engagers

Frontiers in Immunology, 2023
IntroductionWe have recently developed a novel T cell engager concept by utilizing γ9δ2TCR as tumor targeting domain, named gamma delta TCR anti-CD3 bispecific molecule (GAB), targeting the phosphoantigen-dependent orchestration of BTN2A1 and BTN3A1 at ...
Eline van Diest, Mara J. T. Nicolasen, Lovro Kramer, Jiali Zheng, Patricia Hernández-López, Dennis X. Beringer, Jürgen Kuball, Jürgen Kuball   +7 more
doaj   +1 more source

Apoptosis of Fashigh CD4+ synovial T cells by borrelia-reactive Fas-ligand(high) gamma delta T cells in Lyme arthritis [PDF]

, 1996
The function of the minor subset of T lymphocytes bearing the gamma delta T cell antigen receptor is uncertain. Although some gamma delta T cells react to microbial products, responsiveness has only rarely been demonstrated toward a bacterial antigen ...
Alderson, Alderson, Augustin, Bellgrau, Born, Brennan, Carding, Cooper, David Lynch, David Wilson, De Libero, Emoto, French, Gavrieli, Goodman, Griffith, Groh, Haas, Haregewoi, Holoshitz, Huber, Janis, Jurg Tschopp, Kagi, Karen Roessner, Leonard H. Sigal, Lowin, Mariani, McMenamin, Michael S. Vincent, Modlin, Morita, Mukasa, Nagata, O'Brien, Parker, Pelegri, Peterman, Ralph C. Budd, Roessner, Rouvier, Rust, Sgorc, Sheldon M. Cooper, Spencer, Suda, Tanaka, Wright, Yssel   +48 more
core   +2 more sources

Climate change, in the framework of the constructal law [PDF]

, 2011
Here we present a simple and transparent alternative to the complex models of Earth thermal behavior under time-changing conditions. We show the one-to-one relationship between changes in atmospheric properties and time-dependent changes in temperature ...
Alberton, Bruna, Almeida, Jurandy, Miranda, Waner O., Morellato, Leonor Patricia C., Santos, Jefersson A. dos, Torres, Ricardo da S.   +5 more
core   +1 more source

Silent T-cell receptor cutaneous T-cell lymphoma associated to a clonal plasma cell proliferation

Hematology Reports, 2019
Within T-cell lymphomas (TCL) there are 2 entities expressing gamma-delta TCR: hepatosplenic gamma-delta T-cell lymphoma (HSGDTL) and the primary cutaneous gamma-delta T-cell lymphoma (PCGDTL).
Ana Caballero, Silvana Novelli, Anna Mozos, Pilar Garcia Muret, Anna Monter, Jorge Sierra, Javier Briones   +6 more
doaj   +1 more source

Inhibition of Human T-Cell Proliferation by mTOR antagonists requires Non-Coding RNA growth-arrest-specific transcript 5 (GAS5) [PDF]

, 2010
BACKGROUND: Eosinophils are characteristic participants in allergic inflammation. The intracellular signalling mechanisms involved in the migration of eosinophils to sites of allergic inflammation are poorly understood.
Hassan, AM, Maarabouni, MM, Williams, GT
core   +2 more sources

Multiple receptor-ligand interactions direct tissue resident gamma delta T cell activation

Frontiers in Immunology, 2014
Gamma delta T cells represent a major T cell population in epithelial tissues, such as skin, intestine, and lung, where they function in maintenance of the epithelium and provide a crucial first line defense against environmental and pathogenic insults.
Deborah A. Witherden, Kevin eRamirez, Wendy L. Havran   +2 more
doaj   +1 more source

Gamma-delta T lymphocytes coordinate eosinophil influx during allergic responses

Frontiers in Pharmacology, 2012
Tissue eosinophil infiltration, which is a hallmark of allergic and helminthic diseases, is mainly coordinated by T lymphocytes, via the production of eosinophilotactic chemokines.
Maria Das Graças Muller De Oliveira Henriques, Carmen ePenido   +1 more
doaj   +1 more source