Results 11 to 20 of about 200,887 (335)

Clinical applications of gamma delta T cells with multivalent immunity [PDF]

Frontiers in Immunology, 2014
Gamma delta T cells hold promise for adoptive immunotherapy because of their reactivity to bacteria, viruses, and tumors. However, these cells represent a small fraction (1-5%) of the peripheral T-cell pool and require activation and propagation to ...
Drew C Deniger, Judy S Moyes, Laurence JN Cooper   +2 more
doaj   +2 more sources

Gamma delta T cells recognize haptens and mount a hapten-specific response

eLife, 2014
The ability to recognize small organic molecules and chemical modifications of host molecules is an essential capability of the adaptive immune system, which until now was thought to be mediated mainly by B cell antigen receptors.
Xun Zeng, Christina Meyer, Jun Huang, Evan W Newell, Brian A Kidd, Yu-Ling Wei, Yueh-hsiu Chien   +6 more
doaj   +3 more sources

Chitosan Nanoparticles Strengthen Vγ9Vδ2 T-Cell Cytotoxicity Through Upregulation Of Killing Molecules And Cytoskeleton Polarization

International Journal of Nanomedicine, 2019
Li Lin,1,2,* Junyi He,2,* Jiawei Li,2 Yan Xu,2 Jingxia Li,2 Yangzhe Wu1,2 1Zhuhai Precision Medical Center, Zhuhai People’s Hospital, Zhuhai Hospital Affiliated with Jinan University, Jinan University, Zhuhai, Guangdong 519000, People’s ...
Lin L, He J, Li J, Xu Y, Li J, Wu Y
doaj   +1 more source

Chimeric antigen receptor T cells for gamma-delta T cell malignancies. [PDF]

Leukemia, 2022
Wawrzyniecka PA, Ibrahim L, Gritti G, Pule MA, Maciocia PM.   +4 more
europepmc   +5 more sources

Editorial: Understanding Gamma Delta T Cell Multifunctionality - Towards Immunotherapeutic Applications [PDF]

Frontiers in Immunology, 2020
Kenth Gustafsson, Thomas Herrmann, Francesco Dieli, Francesco Dieli   +3 more
doaj   +2 more sources

A prominent cutaneous eruption as a harbinger for aggressive systemic disease: Gamma-delta T-cell lymphoma [PDF]

JAAD Case Reports
Alexandra Rogers, BSc, Michael L. MacGillivary, MD, Peter R. Hull, MBBCh, MMed (Derm), PhD, Sorin Selegean, MD, Lorenzo Cerroni, MD   +4 more
doaj   +2 more sources

Isolated bone marrow gamma/delta T-cell lymphoma: A difficult case to classify according to the current WHO classification of lymphoid malignancies [PDF]

Leukemia Research Reports
Hideto Hyuuga, Naoki Oishi, Takuma Kumagai, Minori Matuura, Ayato Nakadate, Yuma Sakamoto, Jun Suzuki, Megumi Suzuki, Megumi Koshiisi, Ichiro Kawashima, Takeo Yamamoto, Kei Nakajima, Masaru Tanaka, Tetuso Kondo, Keita Kirito   +14 more
doaj   +2 more sources

Gamma‐delta t‐cell lymphomas [PDF]

European Journal of Haematology, 2014
AbstractGamma‐delta T‐cell lymphomas are aggressive and rare diseases originating from gamma‐delta lymphocytes. These cells, which naturally play a role in the innate, non‐specific immune response, develop from thymic precursor in the bone marrow, lack the major histocompatibility complex restrictions and can be divided into two subpopulations: Vdelta1,
Foppoli M., Ferreri A. J. M.
openaire   +2 more sources

Structural analysis of TRG1@ and TRG2@ loci of the ovine immune system

Italian Journal of Animal Science, 2011
The cellular immune system visualizes the world of pathogens largely through its T cell immune receptors (TCRs), a dimer which may be αβ or γδ.
S. Ciccarese, A. Caputi Jambrenghi, E.P. Cribiu, M. Giovinazzo, M.C. Miccoli, G. Vaccarelli   +5 more
doaj   +1 more source

Five layers of receptor signalling in γδ T cell differentiation and activation

Frontiers in Immunology, 2015
The contributions of gamma-delta T cells to immunity to infection or tumours critically depend on their activation and differentiation into effectors capable of secreting cytokines and killing infected or transformed cells.
Sérgio T. Ribeiro, Julie C. Ribot, Bruno eSilva-Santos   +2 more
doaj   +1 more source