Results 21 to 30 of about 77,563 (250)
Sheep TRD@ locus consists of a large number of TRDV elements
Italian Journal of Animal Science, 2011 The T cell receptor (TcR) expressed on mature T lymphocytes is a disulphidelinked heterodimer composed of alpha and beta or gamma and delta glycoprotein subunits.
S. Ciccarese +6 more
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Case Reports in Gastroenterology, 2007 Hepatosplenic gamma/delta T-cell lymphoma is a rare neoplasm of mature gamma/delta T-cells with sinusoidal infiltration of spleen, liver, and bone marrow.
H.A. Lopez Morra +2 more
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Frontiers in Immunology, 2022 Human Vγ9Vδ2 T cells are attractive candidates for cancer immunotherapy due to their potent capacity for tumor recognition and cytolysis of many tumor cell types.
Mei-Ling Liou +6 more
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Human peripheral CD4+ Vdelta1+ gamma delta T cells can develop into alpha beta T cells
Frontiers in Immunology, 2014 The lifelong generation of alpha beta T cells enables us to continuously build immunity against pathogens and malignancies despite the loss of thymic function with age. Consequently, alpha beta T-cell development has to occur independently of the thymus.
Hendrik eZiegler +6 more
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The influence of zoledronate and teriparatide on gamma delta T cells in mice
Journal of Dental Sciences, 2017 Background/purpose: Few studies have investigated the possibility that bisphosphonate-related osteonecrosis of the jaw (BRONJ) might reflect an immune response; however, gamma delta T cells have been shown to significantly decline in the blood of BRONJ ...
Eiki Yamachika +9 more
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Clinical applications of gamma delta T cells with multivalent immunity
Frontiers in Immunology, 2014 Gamma delta T cells hold promise for adoptive immunotherapy because of their reactivity to bacteria, viruses, and tumors. However, these cells represent a small fraction (1-5%) of the peripheral T-cell pool and require activation and propagation to ...
Drew C Deniger +2 more
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Silent T-cell receptor cutaneous T-cell lymphoma associated to a clonal plasma cell proliferation
Hematology Reports, 2019 Within T-cell lymphomas (TCL) there are 2 entities expressing gamma-delta TCR: hepatosplenic gamma-delta T-cell lymphoma (HSGDTL) and the primary cutaneous gamma-delta T-cell lymphoma (PCGDTL).
Ana Caballero +6 more
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Multiple receptor-ligand interactions direct tissue resident gamma delta T cell activation
Frontiers in Immunology, 2014 Gamma delta T cells represent a major T cell population in epithelial tissues, such as skin, intestine, and lung, where they function in maintenance of the epithelium and provide a crucial first line defense against environmental and pathogenic insults.
Deborah A. Witherden +2 more
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The making of multivalent gamma delta TCR anti-CD3 bispecific T cell engagers
Frontiers in Immunology, 2023 IntroductionWe have recently developed a novel T cell engager concept by utilizing γ9δ2TCR as tumor targeting domain, named gamma delta TCR anti-CD3 bispecific molecule (GAB), targeting the phosphoantigen-dependent orchestration of BTN2A1 and BTN3A1 at ...
Eline van Diest +7 more
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Gamma-delta T lymphocytes coordinate eosinophil influx during allergic responses
Frontiers in Pharmacology, 2012 Tissue eosinophil infiltration, which is a hallmark of allergic and helminthic diseases, is mainly coordinated by T lymphocytes, via the production of eosinophilotactic chemokines.
Maria Das Graças Muller De Oliveira Henriques +1 more
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