Results 141 to 150 of about 13,532 (284)

Localized Delivery of the mRNAs Encoding CD47 Inhibitor and Interleukins 12, 15, and 21 Elicits Robust Antitumor Immunity

Advanced Science, Volume 12, Issue 37, October 6, 2025.
The co‐delivery of mRNAs encoding a CD47 inhibitor and a cytokine cocktail (interleukins 12, 15, and 21) via lipid nanoparticles enables effective localized immunotherapy. This strategy not only suppresses tumor progression but also enhances type 1 conventional dendritic cell (cDC1) differentiation and activates CD8+ T cells, thereby inducing robust ...
Tao Jiang, Shuaiyang Jing, Haojun Li, Bao Xiao, Jiahui Jin, Xiu Sun, Juan Wang, Jing Liang, Tongze Cai, Huili Hu, Meilan Wei, Xuanrui Zhong, Yang Ji, Peng George Wang, Jianlong Zhou   +14 more
wiley   +1 more source

METABOLISM AND FUNCTION OF GAMMA GLOBULIN IN ALEUTIAN DISEASE OF MINK

, 1965
David Porter, Frank J. Dixon, Austin E. Larsen   +2 more
openalex   +1 more source

Treatment of Malignant Diseases Associated with Gamma Globulin Abnormalities [PDF]

, 1963
G. Hamilton Fairley
openalex   +1 more source

Inhibition of FOXM1 Synergizes with BH3 Mimetics Venetoclax and Sonrotoclax in Killing Multiple Myeloma Cells through Repressing MYC Pathway

Advanced Science, Volume 12, Issue 37, October 6, 2025.
Relapsed and refractory multiple myeloma remains a major clinical challenge. This study shows that FOXM1 contributes to resistance against BH3 mimetics in multiple myeloma cells. The FOXM1 inhibitor NB73 enhances the effectiveness of BH3 mimetics by reducing FOXM1 expression and suppressing the MYC pathway.
Zhi Wen, Yidan Wang, Kathryn C. Fox, Adam M. Bissonnette, Luke F. Moat, Terrie E. Kitchner, Kelsey Springstroh, Sung Hoon Kim, Dagna S. Sheerar, Patcharon Tanawattanacharoen, Chady A. Leon, Seth O. Fagbemi, John A. Katzenellenbogen, Scott J. Hebbring, Benita S. Katzenellenbogen, Siegfried Janz, Adedayo A. Onitilo   +16 more
wiley   +1 more source

Seasonal variation of anti-Leishmania infantum antibodies and laboratory abnormalities in dogs with leishmaniosis. [PDF]

Parasit Vectors
Cavalera MA, Uva A, Carbonara M, Mendoza-Roldan JA, Roura X, Cerón JJ, Otranto D, Zatelli A.   +7 more
europepmc   +1 more source

Selective gamma-A-globulin deficiency, with dominant autosomal inheritance in a Swiss family.

, 1968
Fabian Stöcker, P. Ammann, Ezequiel A. Rossi   +2 more
openalex   +1 more source

Population pharmacokinetic modelling of prednisolone in systemic lupus erythematosus patients: Analysis of exposure and disease activity

British Journal of Clinical Pharmacology, Volume 91, Issue 10, Page 2854-2864, October 2025.
Abstract Aims Prednisone is a widely used glucocorticoid in the treatment of lupus, although its dosing is often determined empirically. Prednisolone, the active metabolite of prednisone, is found in its free form in the serum. The goal of this study was to develop a population pharmacokinetic model in patients with systemic lupus erythematosus (SLE ...
Naïm Bouazza, Michaela Semeraro, Gabrielle Lui, Léo Froelicher‐Bournaud, Laure Choupeaux, Jean‐Marc Treluyer, Sihem Benaboud, Joelle Terzic, Eric Hachulla, Philippe Remy, Jérôme Harambat, Alexandre Karras, Caroline Rousset‐Rouviere, Anne Jolivot, Zahir Amoura, Eric Daugas, Aurélie Hummel, Rémi Salomon, Jean‐Christophe Lega, Stéphane Decramer, Alexandre Belot, Delphine Gobert, Nathalie Costedoat‐Chalumeau, Stanislas Faguer, Isabelle Melki, Noémie Jourde‐Chiche, Brigitte Bader‐Meunier   +26 more
wiley   +1 more source

Lenalidomide-Associated Liver Injury With Features of Vanishing Bile Duct Syndrome in Multiple Myeloma. [PDF]

Cureus
Alajpur S, Farooq A.
europepmc   +1 more source

Antinuclear factors in rheumatoid arthritis. Increasing organ-non-specificity with increasing reactivity of rheumatoid factor with heterologous gamma globulin. [PDF]

, 1968
P Elling
openalex   +1 more source

Prediction of Lung Cancer Metastasis Using Machine Learning Models Based on Clinical Laboratory Data

Cancer Reports, Volume 8, Issue 10, October 2025.
ABSTRACT Background Lymph node (N) or/and distant metastasis in lung cancer indicates poorer prognosis. While laboratory tests and computed tomography (CT) scans reflect tumor growth and metabolic activity, they usually require combination with other diagnostic methods to effectively assess metastasis, resulting in limited clinical use of these results.
Chao Du, Qi Liu, Yuanyuan Guo, Jun Gong, Ling Yan, Zhijie Li, Changchun Niu   +6 more
wiley   +1 more source