Results 41 to 50 of about 164,677 (312)

Data on excessive risk of cancer from gamma radiation in residents of Bojnurd city

open access: yesData in Brief, 2018
The aim of the data was to measure the absorbed dose of gamma radiation in order to estimate the excessive risk of cancer-induced gamma radiation during the lifetime of Bojnurd residents.
Mohsen Khosroabadi   +3 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Radiation metabolomics. 2. Dose- and time-dependent urinary excretion of deaminated purines and pyrimidines after sublethal gamma-radiation exposure in mice

open access: yes, 2009
Gamma-radiation exposure of humans is a major public health concern as the threat of terrorism and potential hostile use of radiological devices increases worldwide.
Krausz, Kristopher W   +6 more
core   +1 more source

Bridging Imaging and Therapy: A Review of Advances in Neuroradiology and Neuro-Oncology

open access: yesClinical and Translational Neuroscience
Neuroradiology and neuro-oncology are rapidly emerging fields in the diagnosis and treatment of central nervous system (CNS) diseases, including brain tumors.
Venkatraman Pitchaikannu   +10 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

The metabolomic profile of gamma-irradiated human hepatoma and muscle cells reveals metabolic changes consistent with the Warburg effect [PDF]

open access: yes, 2016
The two human cell lines HepG2 from hepatoma and HMCL-7304 from striated muscle were γ-irradiated with doses between 0 and 4 Gy. Abundant γH2AX foci were observed at 4 Gy after 4 h of culture post-irradiation.
Idle, J. R.   +15 more
core   +1 more source

The Inactivation of Pyrogens by Gamma Radiation

open access: yesJournal of Pharmacy and Pharmacology, 1957
Abstract Gamma irradiation in a dose of 5·0 times 106 rad reduced the pyrogenicity of London tap water but 10·0 times 106 rad was required for it to pass the B.P. test, 20 times 106 rad reduced the pyrogenicity of a pyrogen from S. abortus equi but 25 times 106 rad was required before it passed the B.P. test.
T D, WHITTET, W P, HUTCHINSON
openaire   +2 more sources

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Contribution of 4~400 MeV protons galactic cosmic rays to annihilation radiation in orbital gamma spectrum near lunar space

open access: yesHe jishu, 2023
BackgroundThe annihilation radiation exhibits conspicuous features in the low-energy segment of the orbital gamma spectrum, which contains a substantial amount of geological information about the lunar surface.
ZHAO Jiankun   +6 more
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

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