Results 41 to 50 of about 36,242 (250)

Turning a Negative into a Positive: Ascending GABAergic Control of Cortical Activation and Arousal

open access: yesFrontiers in Neurology, 2015
Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the brain. Recent technological advances have illuminated the role of GABAergic neurons in control of cortical arousal and sleep.
Ritchie Edward Brown, James Tim McKenna
doaj   +1 more source

Temporal interactions between cortical rhythms

open access: yesFrontiers in Neuroscience, 2008
Multiple local neuronal circuits support different, discrete frequencies of network rhythm in neocortex. Relationships between different frequencies correspond to mechanisms designed to minimise interference, couple activity via stable phase interactions,
Anita K Roopun   +8 more
doaj   +1 more source

Transcranial alternating current stimulation combined with sound stimulation improves the cognitive function of patients with Alzheimer's disease: A case report and literature review

open access: yesFrontiers in Neurology, 2022
Transcranial alternating current stimulation (tACS) is a relatively new non-invasive brain electrical stimulation method for the treatment of patients with Alzheimer's disease (AD), but it has poor offline effects.
Yang Liu   +7 more
doaj   +1 more source

α‐tACS over the somatosensory cortex enhances tactile spatial discrimination in healthy subjects with low alpha activity

open access: yesBrain and Behavior, 2021
Introduction Spontaneous oscillations in the somatosensory cortex, especially of the alpha (8 − 14 Hz) and gamma (60 − 80 Hz) frequencies, affect tactile perception; moreover, these oscillations can be selectively modulated by frequency‐matched ...
Kei Saito   +6 more
doaj   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen   +7 more
wiley   +1 more source

Bri2 BRICHOS chaperone rescues impaired fast-spiking interneuron behavior and neuronal network dynamics in an AD mouse model in vitro

open access: yesNeurobiology of Disease, 2021
Synchronized and properly balanced electrical activity of neurons is the basis for the brain's ability to process information, to learn, and to remember.
Yuniesky Andrade-Talavera   +4 more
doaj   +1 more source

The influence of external and internal motor processes on human auditory rhythm perception [PDF]

open access: yes, 2012
Musical rhythm is composed of organized temporal patterns, and the processes underlying rhythm perception are found to engage both auditory and motor systems.
Su, Yi-Huang
core  

Increased mesiotemporal delta activity characterizes virtual navigation in humans [PDF]

open access: yes, 2013
Hippocampal theta or rhythmic slow activity (RSA) occurring during exploratory behaviors and rapid-eye-movement (REM) sleep is a characteristic and well-identifiable oscillatory rhythm in animals.
Janszky, József   +9 more
core   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Period concatenation underlies interactions between gamma and beta rhythms in neocortex

open access: yesFrontiers in Cellular Neuroscience, 2008
The neocortex generates rhythmic electrical activity over a frequency range covering many decades. Specific cognitive and motor states are associated with oscillations in discrete frequency bands within this range, but it is not known whether ...
Anita K Roopun   +6 more
doaj   +1 more source

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