Results 1 to 10 of about 25,517 (218)
Anabolic sialosylation of gangliosides in situ in rat brain cortical slices.
Journal of Lipid Research, 1989 Radiolabeling of the sialic acid residues of gangliosides was examined in thin slices of rat brain cerebral cortex incubated under physiologic conditions in the presence of either [14C]N-acetyl-mannosamine (ManNAc) or cytidine 5'-monophosphoryl-[14C]N ...
R Durrie, A Rosenberg
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Differential distribution of major brain gangliosides in the adult mouse central nervous system. [PDF]
PLoS ONE, 2013 Gangliosides - sialic acid-bearing glycolipids - are major cell surface determinants on neurons and axons. The same four closely related structures, GM1, GD1a, GD1b and GT1b, comprise the majority of total brain gangliosides in mammals and birds ...
Katarina Vajn +4 more
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Ganglioside and Non-ganglioside Mediated Host Responses to the Mouse Polyomavirus. [PDF]
PLoS Pathogens, 2015 Gangliosides serve as receptors for internalization and infection by members of the polyomavirus family. Specificity is determined by recognition of carbohydrate moieties on the ganglioside by the major viral capsid protein VP1.
John You +6 more
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Challenges in the Analysis of Gangliosides by LC-MS
CHIMIA, 2022 Gangliosides are a family of conjugates consisting of a polar sialoglycan head group and a hydrophobic ceramide tail. Gangliosides are of high abundance in neuronal tissues and are involved in numerous biological processes, such as cell-cell recognition,
Thomas Muggli +2 more
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Frontiers in Cell and Developmental Biology, 2022 Phenotypic switching between contractile (differentiated state) and proliferative (dedifferentiated state) vascular smooth muscle cells (VSMCs) is a hallmark of vascular remodeling that contributes to atherosclerotic diseases.
Norihiko Sasaki +5 more
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Lipid rafts and human diseases: why we need to target gangliosides
FEBS Open Bio, 2023 Gangliosides are functional components of membrane lipid rafts that control critical functions in cell communication. Many pathologies involve raft gangliosides, which therefore represent an approach of choice for developing innovative therapeutic ...
Jacques Fantini
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Journal of Lipid Research, 1995 Gangliosides in normal serum are found only in lipoproteins and the relative content of the three major lipoprotein fractions is low density lipoprotein > high density lipoprotein > very low density lipoprotein (LDL > HDL > VLDL).
A Rebbaa, J Portoukalian
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Mljekarstvo, 2016 Gangliosides belong to a group of glycosphingolipids which are naturally found in biological tissues and fluids including mammalian milks. Considering milk, gangliosides are exclusively found in the membrane of the milk fat globule.
Slavica Potočki, Marko Mesarić
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Production of multiple brain-like ganglioside species is dispensable for fas-induced apoptosis of lymphoid cells. [PDF]
PLoS ONE, 2011 Activation of an acid sphingomyelinase (aSMase) leading to a biosynthesis of GD3 disialoganglioside has been associated with Fas-induced apoptosis of lymphoid cells. The present study was undertaken to clarify the role of this enzyme in the generation of
Iuliana Popa +5 more
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TNF differentially regulates ganglioside biosynthesis and expression in breast cancer cell lines. [PDF]
PLoS ONE, 2018 Gangliosides are glycosphingolipids concentrated in glycolipid-enriched membrane microdomains. Mainly restricted to the nervous system in healthy adult, complex gangliosides such as GD3 and GD2 have been shown to be involved in aggressiveness and ...
Justine H Dewald +8 more
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