Results 11 to 20 of about 25,517 (218)

The gangliosides

open access: yesJournal of Lipid Research, 1964
The results of recent studies on the complexities of gangliosides from brain, spleen, and erythrocyte stroma are described, and ganglioside nomenclature is discussed.
Lars Svennerholm
doaj   +3 more sources

Chemoenzymatically Synthesized O-Acetylated GD3 Gangliosides to Examine Viral Receptor Specificities in a Cellular Context. [PDF]

open access: yesAngew Chem Int Ed Engl
7‐O‐, 9‐O‐, and 7,9‐di‐O‐acetylated GD3 gangliosides can be prepared by chemical assembly of a tetrasaccharide as α‐glycosyl fluoride that is coupled to sphingosine using a glycosynthase, followed by O‐acetyl editing by coronaviral hemagglutinin‐esterases (HEs).
Zhang Z   +5 more
europepmc   +3 more sources

Ganglioside Biochemistry [PDF]

open access: yesISRN Biochemistry, 2012
Gangliosides are sialic acid-containing glycosphingolipids. They occur especially on the cellular surfaces of neuronal cells, where they form a complex pattern, but are also found in many other cell types. The paper provides a general overview on their structures, occurrence, and metabolism. Key functional, biochemical, and pathobiochemical aspects are
openaire   +2 more sources

Diet-Induced Changes in Spectrum Patterns of Serum Gangliosides in 6-Month-Old Infants

open access: yesMajalah Kedokteran Bandung, 2012
Human milk contains higher levels of gangliosides than infant formula. Gangliosides play a role in neuronal growth, migration and maturation, sinaptogenesis, and myelination.
Dida A. Gurnida   +7 more
doaj   +1 more source

Ganglioside Alters Phospholipase Trafficking, Inhibits NF-κB Assembly, and Protects Tight Junction Integrity

open access: yesFrontiers in Nutrition, 2021
Background and Aims: Dietary gangliosides are present in human milk and consumed in low amounts from organ meats. Clinical and animal studies indicate that dietary gangliosides attenuate signaling processes that are a hallmark of inflammatory bowel ...
John J. Miklavcic   +7 more
doaj   +1 more source

Recovery of gangliosides from aqueous solutions on styrene-divinylbenzene copolymer columns1

open access: yesJournal of Lipid Research, 2002
An investigation was made using a styrene-divinylbenzene copolymer as a solid phase sorbent to recover gangliosides from aqueous solutions. A comparison with octadecyl-bonded (C18) silica gel showed that the general procedure used to purify gangliosides ...
Iuliana Popa   +3 more
doaj   +1 more source

Specific synthesis of neurostatin and gangliosides O-acetylated in the outer sialic acids using a sialate transferase. [PDF]

open access: yesPLoS ONE, 2012
Gangliosides are sialic acid containing glycosphingolipids, commonly found on the outer leaflet of the plasma membrane. O-acetylation of sialic acid hydroxyl groups is one of the most common modifications in gangliosides.
Lorenzo Romero-Ramírez   +6 more
doaj   +1 more source

Characterization and quantitative determination of gangliosides and neutral glycosphingolipids in human liver.

open access: yesJournal of Lipid Research, 1982
The neutral and acidic glycolipids from the liver of an 11-year-old male were quantitatively isolated and characterized. The total concentration of gangliosides was also determined in sampled from five other human livers.
O Nilsson, L Svennerholm
doaj   +1 more source

Anti-inflammatory role of GM1 and other gangliosides on microglia

open access: yesJournal of Neuroinflammation, 2022
Background Gangliosides are glycosphingolipids highly enriched in the brain, with important roles in cell signaling, cell-to-cell communication, and immunomodulation.
Danny Galleguillos   +15 more
doaj   +1 more source

Comprehensive Profiling of Surface Gangliosides Extracted from Various Cell Lines by LC-MS/MS

open access: yesCells, 2019
Gangliosides act as a surface marker at the outer cellular membrane and play key roles in cancer cell invasion and metastasis. Despite the biological importance of gangliosides, they have been still poorly characterized due to the lack of effective ...
Jua Lee   +9 more
doaj   +1 more source

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