Results 21 to 30 of about 25,517 (218)
Frontiers in Oncology, 2016 Glycolipids are complex molecules consisting of a ceramide lipid moiety linked to a glycan chain of variable length and structure. Among these are found the gangliosides, which are sialylated glycolipids ubiquitously distributed on the outer layer of ...
Jose Luis Daniotti +2 more
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Retention of gangliosides in serum delipidated by diisopropyl ether-1-butanol extraction.
Journal of Lipid Research, 1983 Extraction with diisopropyl ether-1-butanol is a rapid method for the delipidation of serum without protein denaturation. We sought to confirm that this solvent system would also extract the highly polar acidic glycosphingolipids, gangliosides.
C G Wong, S Ladisch
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Journal of Lipid Research, 1985 A simple and effective procedure has been developed for eliminating silica gel from gangliosides after preparative thin-layer chromatography. Gangliosides were extracted from the scraped silica gel with chloroform-methanol-water 10:10:3 (by volume) and ...
H Kubo, M Hoshi
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Gangliosides in the Brain: Physiology, Pathophysiology and Therapeutic Applications
Frontiers in Neuroscience, 2020 Gangliosides are glycosphingolipids highly abundant in the nervous system, and carry most of the sialic acid residues in the brain. Gangliosides are enriched in cell membrane microdomains (“lipid rafts”) and play important roles in the modulation of ...
Simonetta Sipione +4 more
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Quantification of gangliosides by microbore high performance liquid chromatography.
Journal of Lipid Research, 1996 A highly sensitive analytical method was developed that allows the separation of ganglioside mixtures and quantification of individual non-derivatized gangliosides in the concentration range between 2 pmol and 1 nmol.
R Wagener, B Kobbe, W Stoffel
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Determination of brain gangliosides by determination of ganglioside stearic acid
Journal of Lipid Research, 1966 A new method is described for the determination of brain gangliosides by measuring stearic acid, the chief acid of gangliosides, in an appropriately purified brain extract.
Yasuo Kishimoto, Norman S. Radin
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Role of gangliosides in the differentiation of human mesenchymal-derived stem cells into osteoblasts and neuronal cells [PDF]
BMB Reports, 2013 Gangliosides are complex glycosphingolipids that are the majorcomponent of cytoplasmic cell membranes, and play a rolein the control of biological processes.
Ghislain Moussavou +6 more
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Mediators of Inflammation, 2016 Mast cells are immunoregulatory cells that participate in inflammatory processes. Cross-linking mast cell specific GD1b derived gangliosides by mAbAA4 results in partial activation of mast cells without the release of preformed mediators.
Edismauro Garcia Freitas Filho +4 more
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Cell Reports, 2018 Summary: Lysosome membrane recycling occurs at the end of the autophagic pathway and requires proteins that are mostly encoded by genes mutated in neurodegenerative diseases. However, its implication in neuronal death is still unclear. Here, we show that
Maxime Boutry +19 more
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The structure of gangliosides hides a code for determining neuronal functions
FEBS Open Bio, 2021 Gangliosides are particularly abundant in the central nervous system, where they are mainly associated with the synaptic membranes. Their structure underlies a specific role in determining several cell physiological processes of the nervous system.
Giulia Lunghi +5 more
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