Results 51 to 60 of about 186,809 (300)

Modeling gap acceptance at freeway merges [PDF]

open access: yes, 2006
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Civil and Environmental Engineering, 2006.Includes bibliographical references (p. 103-105).This thesis develops a merging model that captures the gap acceptance behavior of drivers that merge
Lee, Gunwoo
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Modeling Factors Influencing Motorcycle Riders’ Decision When Facing Pedestrians at Unsignalized Mid-Block Crosswalks: A Case Study from Bangkok

open access: yesCivil and Environmental Engineering
Motorcyclist–pedestrian conflicts at unsignalized mid-block crosswalks represent a critical safety concern, particularly in urban areas of developing countries where motorcycles account for a substantial proportion of the vehicle fleet.
Sutantaviboon Tanawan   +1 more
doaj   +1 more source

Determination of gap acceptance at priority intersections [PDF]

open access: yes, 2014
Vehicles from minor approach at a stop-controlled intersection will wait for an appropriate gap to exist in the conflicting traffic stream before performing the merging or crossing manoeuvres at the intersection.
Sahraei, Mohammad Ali, Che Puan, Othman
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Gap acceptance and Driver behavior at intersections in Minna, North Central Nigeria

open access: yesNigerian Journal of Technological Development, 2010
The headways, spacing distributions and gap acceptance were measured from two main intersections in Minna, Central Nigeria/The average critical gap and spacing for stadium junction are 2.39 seconds and 11.08m respectively, and that of Mustapha hospital ...
P. N. Ndoke, S. S. Kolo
doaj   +2 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Optimizing Intersection Design: Insights From Older Drivers’ Physiological Responses and Gap Acceptance Behavior at Signalized Left Turns

open access: yesIEEE Access
Aging populations pose significant challenges for transportation safety at complex intersections. This study investigated gap acceptance behavior of older drivers at left-turn signalized permissive intersections using a driving simulator with 40 ...
Sneha Srinivasan   +5 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Home - About - Disclaimer - Privacy