Results 101 to 110 of about 8,772,710 (396)

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

A Study on the Creep Characteristics of Gassy Clay Mixed with Silt

Applied Sciences
As the economy evolves, there has been an increasing interest in exploring oceanic resources. However, the complex marine environment poses several geological challenges for offshore engineering endeavors.
Aiwu Yang, Tianli Liu, Hao Zhang, Boqu Zhang   +3 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Delineation and Application of Gas Geological Units for Optimized Large-Scale Gas Drainage in the Baode Mine

Energies
Addressing the challenge of efficient gas control in high-gas coal mines with ultra-long panels, this study focuses on the No. 8 coal seam in the Baode Mine.
Shuaiyin He, Xinjiang Luo, Jinbo Zhang, Zenghui Zhang, Peng Li, Huazhou Huang   +5 more
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Method for calculating the amount of gas loss from confined sampling and its software development

矿业科学学报
Coal seam gas content is a fundamental parameter in the evaluation and development of coalbed methane resources, prediction of coal seam gas protrusion risk as well as prevention and control of gas disasters.
WEN Zhihui, JIA Ran, WEI Jianping, YU Xiao, WAN Zhaoxu, WANG Jianwei, WU Xinliang   +6 more
doaj   +1 more source

Technoeconomic evaluation of flared natural gas reduction and energy recovery using gas-to-wire scheme [PDF]

, 2013
Most mature oil reservoirs or fields tend to perform below expectations, owing to high level of associated gas production. This creates a sub-optimal performance of the oil production surface facilities; increasing oil production specific operating ...
Anosike, Nnamdi Benedict
core  

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Local Content in Tanzania’s Gas and Minerals Sectors: Who regulates?

, 2017
The implementation of Tanzania’s local content policy for the petroleum and mineral sectors has been hampered by inconsistency, confusion, and un-coordinated donor interventions.
Ovadia, Jesse Salah
core   +1 more source