Results 161 to 170 of about 5,337,491 (425)

Prognostic relevance of a T-type calcium channels gene signature in solid tumours: A correlation ready for clinical validation [PDF]

, 2017
BackgroundT-type calcium channels (TTCCs) mediate calcium influx across the cell membrane. TTCCs regulate numerous physiological processes including cardiac pacemaking and neuronal activity.
A Panner, AJ Bass, Alfredo Falcone, AM Szász, B Dziegielewska, B Dziegielewska, B Nilius, C Wu, Caterina Vivaldi, D Kiryushko, D Lin, DE Clapham, Dong Lin, F Lordick, F Lu, Francesco Crea, G Santoni, GE Bertolesi, GR Monteith, Hui Xue, JH Heo, JT Taylor, JZ Press, L Leanza, Lorenzo Fornaro, LS Gray, Martin D. Bootman, MC Iftinca, MC Nowycky, MJ Berridge, NCK Valerie, NH Lester-Coll, P Fogar, P Mariot, PJ Buchanan, Robert M Lafrenie, W Huang, W Li, X Dong, Y Zhang, Y Zhang, Y Zhang, Yuzhuo Wang   +42 more
core   +3 more sources

The role of gastric microbiota in gastric cancer

Gut microbes, 2020
Gastric cancer represents one of the leading causes of cancer deaths worldwide. Helicobacter pylori (H. pylori) infection is the strongest risk factor associated with gastric cancer.
Oliver A Stewart, Fen Wu, Yu Chen
semanticscholar   +1 more source

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

Aging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal, Abhimanyu Chiraparambil Radhakrishnan, Ayanchetty Haripraba, Saif Syed, Gajawada Pragna, Ayush Dwivedi, Akash Rawat, Daniela Castro Calderón, Martin Cevallos‐Cueva   +8 more
wiley   +1 more source

Key nodal stations for predicting splenic hilar nodal metastasis in upper advanced gastric cancer without invasion of the greater curvature

Annals of Gastroenterological Surgery
Background Standard surgery for upper advanced gastric cancer without invasion of the greater curvature (UGC‐GC) is spleen‐preserving D2 total gastrectomy without dissection of the splenic‐hilar nodes (#10).
Masashi Nishino, Takaki Yoshikawa, Masahiro Yura, Rei Ogawa, Ryota Sakon, Kenichi Ishizu, Takeyuki Wada, Tsutomu Hayashi, Yukinori Yamagata   +8 more
doaj   +1 more source

Investigation of the potential role of checkpoint kinase2 in the regulation of gastric cancer stem cells [PDF]

, 2018
Purpose: To investigate the potential role of checkpoint kinase2 (CHEK2) in regulating gastric cancer stem cells.Methods: The abnormal features of cellular arrangements in early and advanced stages of gastric cancer were analysed using histology ...
Ji, Lin-Hua, Zhang, Bin, Zhao, Gang
core   +2 more sources

Acute WNT signalling activation perturbs differentiation within the adult stomach and rapidly leads to tumour formation [PDF]

, 2013
A role for WNT signalling in gastric carcinogenesis has been suggested due to two major observations. First, patients with germline mutations in adenomatous polyposis coli (APC) are susceptible to stomach polyps and second, in gastric cancer, WNT ...
A Gregorieff, A Horii, A Jung, A Novak, AC de Vries, AN Milne, AT Franco, B Kim, B Tycko, C Cavard, D Athineos, D M Pritchard, DM Parkin, E Half, E Tahara, EF Chan, G Gatta, H Guillen-Ahlers, H Ireland, H Luche, H Nagase, H Oshima, H Shibata, H Watanabe, H Zhang, HC Zheng, HJ Freeman, J Cordero, J Neumann, J Parsonnet, J Woodgett, JG Forte, K Miyazawa, K Oien, KF Becker, KW Kinzler, LK Bianchi, M Crabtree, M Iida, M Nakayama, M Shitashige, M Suzuki, M Suzuki, M Torbenson, MG Smith, MP Ebert, N Barker, N Barker, N Barker, N Barker, N Barker, N Harada, N Murata-Kamiya, N Uemura, O J Sansom, O Sokolova, O Tetsu, OJ Sansom, P Blache, P Correa, P Correa, P Lauren, P Salgueiro, P Soriano, PJ Guilford, R A Ridgway, R Kemp, R Poulsom, S Garrean, S Nakatsuru, S Patel, S Patel, S Radulescu, S Segditsas, S Sekine, SC Abraham, SC Abraham, SM Przemeck, SS Ng, T Gnad, T Oda, TC He, WM Clements, WS Park, XC He, Y Miyoshi, Y Park do, Z Spicer, Z Zhao   +88 more
core   +1 more source

Effect of Laparoscopic vs Open Distal Gastrectomy on 3-Year Disease-Free Survival in Patients With Locally Advanced Gastric Cancer: The CLASS-01 Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2019
Importance Laparoscopic distal gastrectomy is accepted as a more effective approach to conventional open distal gastrectomy for early-stage gastric cancer. However, efficacy for locally advanced gastric cancer remains uncertain.
Jiang Yu, Chang-ming Huang, Yihong Sun, X. Su, H. Cao, Jian-kun Hu, Kuan Wang, J. Suo, K. Tao, Xianli He, Hongbo Wei, M. Ying, Wei-guo Hu, Xiao-hui Du, Yanfeng Hu, Hao Liu, C. Zheng, Ping Li, Jian-Wei Xie, Fenglin Liu, Ziyu Li, Gang Zhao, Kun Yang, Chunxiao Liu, Haojie Li, Pingyan Chen, J. Ji, Guoxin Li   +27 more
semanticscholar   +1 more source

Gastric Cancer [PDF]

Gastroenterology Clinics of North America, 2013
This review provides a state of the art description of gastric cancer etiology, the infectious agent, host factors, the precancerous cascade, clinical aspects, and prevention strategies. The biology of Helicobacter pylori, the primary causative agent, is discussed as well as the environmental factors that may modulate its effects.
openaire   +3 more sources

Expression of transforming growth factor beta-1 in gastric cancer and in the gastric mucosa of first-degree relatives of patients with gastric cancer [PDF]

, 2000
Transforming growth factors beta (TGF-β) constitute a family of polypeptide growth factors that control cell growth, cell differentiation and migration, as well as the formation of the extracellular matrix.
Boeing H, Correa P, Delchier JC, E Bayerdörffer, Ebert M, Ebert M, Friess H, Fuchs CS, G Fei, J Yu, K Ridwelski, Kingsley D, La Vecchia C, M P A Ebert, M Stolte, Macklin MT, Mahara K, Massague J, Meining A, Miehlke S, Muso E, Naef M, Nakamura M, Nakatsuru S, Ottini L, P Malfertheiner, Price AB, S Miehlke, Scott N, Soman NR, Tahara E, U Lendeckel, Wright PA   +32 more
core   +2 more sources

Effects of cardiac motion on dose distribution during stereotactic arrhythmia radioablation treatment: A simulation and phantom study

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Cardiac motion may degrade dose distribution during stereotactic arrhythmia radioablation using the CyberKnife system, a robotic radiosurgery system. This study evaluated the dose distribution changes using a self‐made cardiac dynamic platform that mimics cardiac motion. Methods The cardiac dynamic platform was operated with amplitudes
Takayuki Miyachi, Takeshi Kamomae, Fumitaka Kawabata, Kuniyasu Okudaira, Mariko Kawamura, Shunichi Ishihara, Shinji Naganawa   +6 more
wiley   +1 more source