Results 61 to 70 of about 5,282,959 (357)

Epidemiology of gastric cancer: global trends, risk factors and prevention

open access: yesGastroenterology Review, 2018
Gastric cancer remains one of the most common and deadly cancers worldwide, especially among older males. Based on GLOBOCAN 2018 data, stomach cancer is the 5th most common neoplasm and the 3rd most deadly cancer, with an estimated 783,000 deaths in 2018.
Prashanth Rawla, A. Barsouk
semanticscholar   +1 more source

Nutrition and Gastric Cancer [PDF]

open access: yesCanadian Journal of Gastroenterology and Hepatology, 2000
The reasons for the worldwide decline in stomach cancer incidence and mortality rates are not fully understood, but dietary changes are clearly implicated. While the possible mechanisms of gastric carcinogenesis and the impact of Helicobacter pylori eradication remain open to debate, at least two practical recommendations – to increase fruit and ...
C. La Vecchia, S. Franceschi
openaire   +4 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

Survival outcomes of laparoscopic versus open total gastrectomy with nodal dissection for gastric cancer in a high‐volume Japanese center: A propensity score‐matched analysis

open access: yesAnnals of Gastroenterological Surgery, 2023
Aim To compare the survival outcomes of laparoscopic total gastrectomy (LTG) with those of open total gastrectomy (OTG) in gastric cancer. Methods Using an in‐house database, this single‐center study reviewed clinical data for patients who underwent ...
Takahiro Kinoshita   +3 more
doaj   +1 more source

Focus on gastric cancer [PDF]

open access: yesCancer Cell, 2004
Severe dysplasia/noninvasive mucosal carcinoma could contain different entities that have different abilities to invade the lamina propria mucosae. However, key molecular alterations that determine this progression are unknown. The presence of lymph node or distant metastasis is a very important factor in deciding a treatment strategy, but accurate ...
Mitsuru Sasako, Toshikazu Ushijima
openaire   +3 more sources

Treatment of Gastric Cancer [PDF]

open access: yesCancers, 2020
Surgery represents the only method for potentially curative intent for gastric cancer (GC) [...]
Stefano Rausei, Georgios D. Lianos
openaire   +3 more sources

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

Family History of Gastric Cancer and Helicobacter pylori Treatment.

open access: yesNew England Journal of Medicine, 2020
BACKGROUND Helicobacter pylori infection and a family history of gastric cancer are the main risk factors for gastric cancer. Whether treatment to eradicate H.
I. Choi   +6 more
semanticscholar   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

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