Results 161 to 170 of about 3,866,464 (201)

Trophic effects of continuous infusion of [Leu15]-gastrin-17 in the rat

Gastroenterology, 1990
This report describes the trophic effects of exogenous gastrin on the digestive tract and pancreas and the effect on the density of enterochromaffinlike cells in the oxyntic mucosa of the stomach. Female rats were given 1.2 or 2.4 nmol/kg.h of synthetic human [Leu15]-gastrin-17 for 28 days (via osmotic minipumps implanted subcutaneously).
B, Ryberg, J, Axelson, R, Håkanson, F, Sundler, H, Mattsson   +4 more
openaire   +2 more sources

Effect of Gastrin-17 on Lower Esophageal Sphincter Characteristics in Man

Digestive Diseases and Sciences, 1997
We studied the effect of gastrin-17 on lower esophageal sphincter (LES) characteristics in man. Nine healthy volunteers participated in two experiments performed in random order during continuous infusion of saline (control) or gastrin-17 (15 pmol/kg/hr).
J W, Straathof, C B, Lamers, A A, Masclee   +2 more
openaire   +2 more sources

Development of a time-resolved fluorescence immunoassay based on immunomagnetic beads for gastrin-17

Journal of Immunological Methods, 2021
In this study, a novel, simple, and rapid immunoassay for the determination of gastrin-17 (G-17) in human serum was established by combining immunomagnetic beads with time-resolved fluorescence immunoassay (TRFIA).Immunomagnetic beads were coated with anti-G-17 M01 antibody, anti-G-17 M02 antibody was labeled with Eu3+ chelates.
Shaoxiong, Zheng, Renjing, Hu, Xiaomei, Yu, Lingli, Chen, , BinrongWang, Yuan, Qin, Xiumei, Zhou, Yigang, Wang, Biao, Huang, Hongming, Fang, Pengfei, Liu   +10 more
openaire   +2 more sources

Gastrin 17 and Gastrin 34, Before and After a Meal, in Newborn Infants

Journal of Pediatric Gastroenterology and Nutrition, 1987
SummaryIn 89 healthy full‐term newborn infants, we studied the different contribution of gastrin 17 (G17) and gastrin 34 (G34) to neonatal hypergastrinemia and the G17 and G34 response to a meal in the first days of life. Serum concentrations of G17 and G34 were measured by radioimmunoassay specific for the NH2‐terminus of G17 and G34 in 23 newborn ...
GEMELLI M, MAMÌ C, MANGANARO, Rosa, ARTEMISIA A, CONTI NIBALI S, MAGAZZU', Giuseppe, LOMBARDO G.   +6 more
openaire   +4 more sources

Immune response to gastrin-17 and survival in gastrointestinal cancers.

Journal of Clinical Oncology, 2010
e14541 Background: Gastrin is a potential growth factor for tumors arising within the gastrointestinal tract.
J. M. Oortgiesen, L. A. DiMichele, J. R. Weidman, V. T. Gunto, T. Soeder, A. Cato, L. Sutton   +6 more
openaire   +1 more source

Probiotic intervention decreases serum gastrin-17 in Helicobacter pylori infection

Digestive and Liver Disease, 2007
Previously we showed that a probiotic combination with L. rhamnosus GG was beneficial as an adjuvant therapy during H. pylori eradication.To evaluate whether probiotic combination with LGG adheres to the upper gastrointestinal mucosa and modifies H. pylori colonisation and H. pylori induced inflammation.Thirteen patients referred for gastroduodenoscopy
E, Myllyluoma, K, Kajander, H, Mikkola, S, Kyrönpalo, M, Rasmussen, E, Kankuri, P, Sipponen, H, Vapaatalo, R, Korpela   +8 more
openaire   +2 more sources

Phosphorylation of gastrin-17 by epidermal growth factor-stimulated tyrosine kinase

Nature, 1983
Tyrosine phosphorylation seems to be a key event in the control of cellular growth. Several viral transforming proteins, including the src protein of Rous sarcoma virus, the p120 protein of Abelson leukaemia virus and the middle T antigen of polyoma virus, are phosphorylated by associated tyrosine kinases.
G S, Baldwin, J, Knesel, J M, Monckton
openaire   +2 more sources

Acid Secretory Potency and Elimination of the 15-Leucine Gastrin-17 Analogue in Man

Scandinavian Journal of Gastroenterology, 1981
The effect on gastric acid secretion and the elimination of a commercially available synthetic human gastrin analogue (15-Leucine Synthetic Human Gastrin I, 15-LSG) were studied in six healthy human subjects. On a molar basis acid secretory efficacy was approximately four times greater than pentagastrin and secretory potency ten times greater ...
B, Petersen, J, Christiansen, J F, Rehfeld   +2 more
openaire   +2 more sources

The N-terminal tridecapeptide fragment of gastrin-17 inhibits gastric acid secretion

Regulatory Peptides, 1983
After a meal the serum concentrations of the N-terminal tridecapeptide-like fragment of gastrin-17, (1-13)G-17, increased markedly in patients with active duodenal ulcer, but less so in healthy subjects. Consequently the synthetic (1-13)G-17 was infused intravenously in doses that resulted in concentrations similar to those measured in duodenal ulcer ...
B, Petersen, J, Christiansen, J F, Rehfeld   +2 more
openaire   +2 more sources

Cholecystokinins but not gastrin-17 release calcitonin from thyroid C-cells in the rat

Regulatory Peptides, 1988
Subcutaneous injections of gastrin-17, cholecystokinin-39, cholecystokinin-8 (sulfated and non-sulfated forms), cholecystokinin-4 or pentagastrin induced hypocalcemia in rats. The hypocalcemia was associated with calcitonin release for pentagastrin and the cholecystokinins but not for gastrin-17, even at very high doses.
P, Persson, T, Grunditz, J, Axelson, F, Sundler, R, Håkanson   +4 more
openaire   +2 more sources