Gain-of-function oncogenic mutations in TP53 enhance defined factor-mediated cellular reprogramming [PDF]
Cancer is a disorder with various genetic and epigenetic alterations. Genetic alterations such as mutations, i.e., substitutions, amplifications, and deletions of nucleotide sequences, are largely irreversible, whereas epigenetic alterations can be ...
Dyah Laksmi Dewi +9 more
core +2 more sources
Background Failure to rescue (FTR), defined as a postoperative complication leading to death, is a recently described outcome metric used to evaluate treatment quality.
Masahiro Fukada +9 more
doaj +1 more source
EUS-Guided Pancreatic Cyst Ablation: a Clinical and Technical Review [PDF]
Purpose of Review Pancreatic cystic lesions represent a growing public health dilemma, particularly as our population ages and cross-sectional imaging becomes more sensitive.
DeWitt, John M. +2 more
core +1 more source
Reactivation of hepatitis B virus with immune-escape mutations after ocrelizumab treatment for multiple sclerosis [PDF]
Ocrelizumab is an anti-CD20 monoclonal antibody for the treatment of multiple sclerosis (MS) that is closely related to rituximab. We describe a case of hepatitis B virus (HBV) reactivation in an MS patient with resolved HBV infection receiving ...
Altieri, Marta +11 more
core +1 more source
Single-incision laparoscopic surgery for intestinal intussusception due to neuroendocrine tumor
Background Small intestinal neuroendocrine tumor (NET) is uncommon, but intestinal intussusception caused by NET is even rare. We report a rare case of single-incision laparoscopic surgery (SILS) for intestinal intussusception due to NET G1.
Toshinori Sueda +10 more
doaj +1 more source
Intestinal perforation after surgical treatment for incisional hernia. iatrogenic or idiopathic? [PDF]
Intestinal perforation (IP) is a life-threatening gastroenterological condition requiring urgent surgical care, which may present itself as an uncommon complication following incisional hernia repair surgery, most often because of iatrogenic traumatism ...
Amorosi, V +5 more
core +1 more source
Endoscopic surgery in gastroenterology
From 1983 to 1992, 4,000 operations, 162 endoscopic papillosphincterotomies were performed in the departments of the Republican Clinical Hospital for cholecystitis and its complications; 3836 laparoscopies were performed on a planned and urgent basis for various diseases of the abdominal cavity.
S. V. Abuladze +3 more
openaire +1 more source
Background Postoperative pancreatic fistula (POPF) is a major complication of pancreatic surgery. Drain fluid amylase concentration (DAC) is considered a predictive indicator of POPF. However, other indicators related to postoperative drain fluid amylase
Masahiro Fukada +10 more
doaj +1 more source
Insulin resistance associates with hepatic lobular inflammation in subjects with obesity [PDF]
Purpose: Obese subjects with nonalcoholic fatty liver disease (NAFLD) are more prone to develop additional metabolic disturbances such as systemic insulin resistance (IR) and type 2 diabetes.
Batens, Arsène-Hélène +8 more
core +1 more source
Improved Resection and Outcome of Colon-Cancer Liver Metastasis with Fluorescence-Guided Surgery Using In Situ GFP Labeling with a Telomerase-Dependent Adenovirus in an Orthotopic Mouse Model. [PDF]
Fluorescence-guided surgery (FGS) of cancer is an area of intense development. In the present report, we demonstrate that the telomerase-dependent green fluorescent protein (GFP)-containing adenovirus OBP-401 could label colon-cancer liver metastasis in ...
Bouvet, Michael +10 more
core +7 more sources

