Results 51 to 60 of about 415,933 (291)

Comprehensive Insights into Tracheoesophageal Fistula Pathophysiology, Diagnosis, Treatment, and Future Directions

open access: yesAdvanced Science, EarlyView.
Tracheoesophageal fistula (TEF), a pathological trachea‐esophagus connection, arises congenitally or from malignancy/radiotherapy/trauma, causing aspiration and malnutrition. Diagnosis utilizes imaging and endoscopy. Treatment ranges from endoscopic stenting to surgical repair and conservative management.
Gang Li   +10 more
wiley   +1 more source

COVID‐19 and its effects on the digestive system and endoscopy practice

open access: yesJGH Open, 2020
The Coronavirus Disease 2019 (COVID‐19) is a respiratory illness caused by the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) and has been classified as a pandemic by the World Health Organization in March 2020.
Enrik John T. Aguila   +7 more
doaj   +1 more source

Hepatic ENTPD5 Is Critical for Maintaining Metabolic Homeostasis and Promoting Brown Adipose Tissue Thermogenesis

open access: yesAdvanced Science, EarlyView.
ENTPD5‐mediated conversion of extracellular adenosine triphosphate to ADP of hepatocytes is critical for maintaining hepatic glucose/lipid metabolism and promoting brown adipose tissue thermogenesis via the inhibition of adrenomedullin expression and secretion.
Rufeng Ma   +9 more
wiley   +1 more source

Igfbp2 Downregulation in PVT‐CeA Glutamatergic Circuits Drives Neonatal Anesthesia‐Induced Fear Memory Deficits

open access: yesAdvanced Science, EarlyView.
Repeated neonatal sevoflurane exposure impairs adolescent fear memory through Igfbp2 downregulation in paraventricular thalamus‐central amygdala glutamatergic projections. Restoring Igfbp2 or activating this circuit rescues memory deficits, neuronal excitability, and spine density, identifying a precise molecular target for preventing anesthesia ...
Weiming Zhao   +16 more
wiley   +1 more source

IL-35 Ameliorates Myocardial Strain in Mice with T2DM-Induced Cardiac Injury: Assessment by Layer-Specific Strain

open access: yesDiabetes, Metabolic Syndrome and Obesity
Ziying Wang,1,* Leilei Han,2,* Mingyi Dong,3 Yunman Liu,2 Xiangsui Hu,1 Long Huang,4 Chunquan Zhang,1 Liangyun Guo,1 Shengbo Liu,5 Lingmin Liao1 1Department of Ultrasound, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang ...
Wang Z   +9 more
doaj  

Ensuring the Future Pool of Gastroenterologists in the United Kingdom Is Imperative

open access: yesJGH Open
This perspective article explores the importance of fostering interest in gastroenterology among medical students and addressing the barriers that deter them from pursuing careers in this specialty.
Hareesha Rishab Bharadwaj   +4 more
doaj   +1 more source

Impact of COVID-19 on the Gut: A Review of the Manifestations, Pathology, Management, and Challenges

open access: yesActa Medica Indonesiana, 2021
SARS-CoV-2 is a virus that can enter its hosts through the Angiotensin Converting Enzyme-2 (ACE2) receptor. ACE2 is mainly expressed in cells of the gastrointestinal tract, such as the esophageal epithelium and enterocytes from the ileum-colon ...
Kresna Dharma Suryana   +2 more
doaj  

Tead1a Initiates Transcriptional Priming Through the TEAD1a/YAP‐Notch1‐Spi1/Cebpα Axis to Promote Neutrophil Fate

open access: yesAdvanced Science, EarlyView.
This study discovered that the protein TEAD1a is crucial for neutrophil development. In zebrafish models, disrupting TEAD1a or its interaction with partner protein YAP1 caused severe neutrophil deficiency. TEAD1a functions during the early HSC stage, activates Notch1 signaling in the GMP stage, and triggers Spi1 and Cebpα to drive neutrophil terminal ...
Wang Yiqin   +7 more
wiley   +1 more source

Trend of Representation of Women in Gastroenterology, Hepatology, and Endoscopy Conferences in Asia

open access: yesJGH Open
Objectives Despite progress in promoting gender equality, gender bias remains a significant obstacle for women and hinders their academic advancement. We aim to survey and critically analyze women's representation in conferences and changes over time in ...
Jalpa Devi   +9 more
doaj   +1 more source

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