Results 61 to 70 of about 415,933 (291)

Paediatric endoscopy by adult gastroenterologists in Ile-Ife, Nigeria: A viable option to increase the access to paediatric endoscopy in low resource countries

open access: yesAfrican Journal of Paediatric Surgery, 2015
Background: Paediatric endoscopy performed by adult gastroenterologists is a service delivery model that increases the access of children to endoscopy in countries where paediatric gastroenterologists with endoscopy skills are scarce. However, studies on
Olusegun I Alatise   +3 more
doaj   +1 more source

Src Reduces Neutrophil Extracellular Traps Generation and Resolves Acute Organ Damage

open access: yesAdvanced Science, EarlyView.
Src reduces neutrophil extracellular traps (NETs) generation and resolves acute organ damage. Src directly activates RAF1 by regulating phosphorylation at the Ser 621 site and mediates the RAF/MEK/ERK pathway, thereby affecting the intracellular ROS production. Alternatively, Src activates the RAF1/MEK/ERK pathway by mediating PKC phosphorylation.
Guotao Lu   +18 more
wiley   +1 more source

The British Society of Gastroenterology [PDF]

open access: bronze, 1969
H T Howat   +18 more
openalex   +3 more sources

Factors influencing gastroenterology specialist trainees’ satisfaction with the regional speciality educational programme

open access: yesMedEdPublish, 2017
All post-graduate training programmes in the United Kingdom follow relevant competency-based curricula. Whilst much of trainees learning occurs during the day-day activities of their training posts, all training programmes support their trainees with a ...
Ian Beales
doaj  

Akkermansia muciniphila‐Derived N‐Acetylspermidine Modulates the Localization of Intestinal α1,2‐Fucosylated Proteins to Maintain Gut Homeostasis

open access: yesAdvanced Science, EarlyView.
This study demonstrates that Akkermansia muciniphila alleviates colitis by enhancing intestinal α1,2‐fucosylation through its metabolite N‐acetylspermidine. Mechanistically, N‐acetylspermidine‐induced PIM1 inhibition promotes HDAC2‐mediated reduction of chromatin accessibility at TP73, thereby upregulating C1GALT1C1 to boost α1,2‐fucosylation.
Ye Yao   +10 more
wiley   +1 more source

Green Endoscopy and Sustainable Practices: A Scoping Review

open access: yesJournal of Digestive Endoscopy
Objectives The emergence of “green endoscopy” arises from the increasing global need to reform environmental sustainability due to climate change.
Thai Hau Koo   +4 more
doaj   +1 more source

Engineering DNA Origami Captors for TGFβ1 Sequestration to Enhance Tumor Immune Modulation and Therapy

open access: yesAdvanced Science, EarlyView.
Programmable DNA framework captors effectively deplete circulatingtransforming growth factor‐β1 (TGFβ1) through fast systemic clearance and reshape the tumor immune microenvironment, alleviating immunosuppression to inhibit tumor progression. Abstract Efficient modulation of pivotal immune‐regulatory molecules to leverage the tumor microenvironment ...
Xiao Chen   +7 more
wiley   +1 more source

Software as a Medical Device (SaMD) in Digestive Healthcare: Regulatory Challenges and Ethical Implications

open access: yesDiagnostics
The growing integration of software in healthcare, particularly the rise of standalone software as a medical device (SaMD), is transforming digestive medicine, a field heavily reliant on medical imaging for both diagnosis and therapeutic interventions ...
Miguel Mascarenhas   +10 more
doaj   +1 more source

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