Results 91 to 100 of about 580,716 (298)

Release of nutrients and exorphins during in vitro static gastrointestinal digestion of spaghetti from durum wheat

, 2014
Consumption of wheat-derived products has been linked with significant nutritional and health impacts such as the management of glycaemic index and the onset of immunological reactions.
A. Marti, V. Micard, S. Cattaneo, A. Ferraretto, P. De Luca, M.A. Pagani, I. De Noni, M. Stuknyte   +7 more
core   +2 more sources

Functional vegan soups as bioactive food matrices: Evolution of polyphenol content and anticholinesterase activity during simulated gastrointestinal digestion

Journal of Functional Foods
This study investigated digestion-driven changes in polyphenol content, Maillard reaction products, and cholinesterase inhibitory activity in mushroom-, asparagus-, leek-, and sea buckthorn-based vegan soups. These polyphenol-rich, plant-based soups were
Dorota Gajowniczek-Ałasa, Joanna Grzelczyk, Ewa Baranowska-Wójcik, Dominik Szwajgier   +3 more
doaj   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li, Bin Zhang, Zhiqiu Zhang, Bing Zheng, Linhui Han, Chen Yan, Jialin Li, Kaiqiang Sun, Tianyi Zhao, Jiangang Shi   +9 more
wiley   +1 more source

Gut Microbiota‐Isoallolithocholic Acid Crosstalk Promotes Calcium Oxalate Kidney Stone Formation via PARP1‐Mediated Parthanatos

Advanced Science, EarlyView.
ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou, Ruixi Yu, Xuan Zhou, Feng Shi, Zeyu Lin, Peng Gao, Lujia Wang, Ninghan Feng, Zhong Wu, Dawei Wang   +9 more
wiley   +1 more source

Targeting the PHB2–ACSL3 Lipid‐Remodeling Axis Overcomes Cisplatin Resistance by Restoring Ferroptosis in Gastric Cancer

Advanced Science, EarlyView.
ABSTRACT Platinum‐based chemotherapy resistance remains a major obstacle in gastric cancer (GC) treatment. Through integrated transcriptomic profiling of cisplatin‐resistant xenografts and pharmacogenomic interrogation of the NCI‐60 dataset, we identified Prohibitin‐2 (PHB2) as a previously unrecognized determinant of chemoresistance.
Liang Xu, Wanying Xiang, Xinyue Wang, Yue Pan, Jing Gao, Jiezhen Yang, Yufei Wang, Zhipu Zhu, Man Tong, Lei Jin, Yan Ye   +10 more
wiley   +1 more source

Anaerobic digestion in sustainable biomass chains [PDF]

, 2009
This thesis evaluates the potential contribution of anaerobic digestion (AD) to the sustainability of biomass chains. Results provide insights in the technological potential to recover energy and valuable by-products from energy crops and residues, and ...
Pabon Pereira, C.P.
core  

Starch Microstructure and Starch Hydrolysis in Barley and Oat Tempe During In Vitro Digestion.

, 2012
Various botanical and structural characteristics of starchy foods are considered to modify the rate of starch digestion and the glycaemic responses in humans.
Kidman, Siv, Larsson Alminger, Marie, Eklund-Jonsson, Charlotte,, Langton, Maud,, Eklund-Jonsson, Charlotte, Kidman, Siw,, Langton, Maud, Eklund Jonsson, Charlotte, Alminger Larsson, Marie,   +8 more
core   +1 more source

Thermophilic anaerobic digestion of food waste

, 2014
There is a requirement in the European Union to divert organic wastes from landfill because of the risk of methane emissions. One alternative is anaerobic digestion of organic wastes, such as food waste, to stabilise them whilst at the same time ...
Yirong, Chaowana
core   +1 more source

Uhrf1‐Mediated PKM2 Degradation via Ubiquitination Alleviates Inflammation and Pyroptosis in Inflammatory Bowel Disease

Advanced Science, EarlyView.
Uhrf1‐mediated PKM2 ubiquitination and degradation repressed the nuclear translocation of PKM2, and EPT served as a molecular glue capable of targeting the Uhrf1–PKM2 complex to alleviate the IBD course, suggesting that the Uhrf1–PKM2 axis was a previously unrecognized strategy for treating IBD.
Juan Zhang, Xin‐Rong Xu, Hui‐Lin Zhang, Qi‐Meng Zhu, Xin‐Yuan Li, Xi‐Peng Shang, Jing‐Hui Du, Christophe Morisseau, Feng Qiu, Cheng‐Peng Sun   +9 more
wiley   +1 more source

The Cancer Cell Metabolic Reprogramming Remodels the Tumor Microenvironment: Molecular Mechanisms and Therapeutic Strategies

Advanced Science, EarlyView.
This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang, Zhicheng Zhou, Xue Jiang, Zhenguang Du, Yangyang Zhan, Xinli Liu   +5 more
wiley   +1 more source