Results 91 to 100 of about 774,427 (331)

Spontaneous episodic inflammation in the intestines of mice lacking HNF4A is driven by microbiota and associated with early life microbiota alterations

open access: yesmBio, 2023
The inflammatory bowel diseases (IBD) occur in genetically susceptible individuals who mount inappropriate immune responses to their microbiota leading to chronic intestinal inflammation.
Cecelia Kelly   +10 more
doaj   +1 more source

Characterization of the fecal microbiome in cats with inflammatory bowel disease or alimentary small cell lymphoma. [PDF]

open access: yes, 2019
Feline chronic enteropathy (CE) is a common gastrointestinal disorder in cats and mainly comprises inflammatory bowel disease (IBD) and small cell lymphoma (SCL).
Ackermann, Mark R   +9 more
core   +1 more source

The Gut Microbiome in Neuromyelitis Optica. [PDF]

open access: yes, 2017
Neuromyelitis optica (NMO) is a rare, disabling, sometimes fatal central nervous system inflammatory demyelinating disease that is associated with antibodies ("NMO IgG") that target the water channel protein aquaporin-4 (AQP4) expressed on astrocytes ...
Baranzini, Sergio E   +3 more
core   +1 more source

Bile Acid Receptor Therapeutics Effects on Chronic Liver Diseases [PDF]

open access: yes, 2020
In the past ten years, our understanding of the importance of bile acids has expanded from fat absorption and glucose/lipid/energy homeostasis into potential therapeutic targets for amelioration of chronic cholestatic liver diseases.
Alpini, Gianfranco   +4 more
core   +1 more source

AhR‐Dependent Induction of β‐Defensin 1 in Colonic Epithelial Cells Regulates Cross‐Talk between Gut Microbiota and Immune Response Leading to Attenuation of Colitis

open access: yesAdvanced Science, EarlyView.
This study identifies a key signaling pathway involving the environmental sensor AhR and antimicrobial peptides, such as BD‐1, in the regulation of intestinal homeostasis. It highlights the role of BD‐1 in regulating gut microbiota and the intestinal immune response.
Manikandan Palrasu   +16 more
wiley   +1 more source

AI‐Driven Defecation Analysis by Smart Healthcare Toilet: Exploring Biometric Patterns and Eu‐Tenesmus

open access: yesAdvanced Science, EarlyView.
A healthcare toilet system is introduced to passively measure defecation behavior. Real‐time data on stool dropping duration, thickness, and a newly defined “eu‐tenesmus” interval show correlations with stool form and gender differences. Results from 45 defecation events reveal a promising method for comprehensive defecation analysis.
Zhiquan Song   +16 more
wiley   +1 more source

The regulation of host defences to infection by the microbiota [PDF]

open access: yes, 2016
The skin and mucosal epithelia of humans and other mammals are permanently colonised by large microbial communities (the microbiota). Due to this life-long association with the microbiota, these microbes have an extensive influence over the physiology of
Brown, RL, Clarke, TB
core   +1 more source

The gastrointestinal microbiome and its association with the control of pathogens in broiler chicken production: A review

open access: yesPoultry Science, 2017
The microbiome of the broiler chicken gastrointestinal tract (GIT) has been extensively studied, and it has been amply demonstrated that it plays an important role in the health of the host, as it has a positive impact on the immune system, the ...
V. Clavijo   +1 more
semanticscholar   +1 more source

Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC

open access: yesHepatology, EarlyView., 2022
Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu   +11 more
wiley   +1 more source

Micromanagement in the gut : microenvironmental factors govern colon mucosal biofilm structure and functionality [PDF]

open access: yes, 2015
The human gut microbiome provides us with functional features that we did not have to evolve ourselves and can be viewed as a structured microbial community that operates like a microbial organ within the human host.
De Weirdt, Rosemarie, Van de Wiele, Tom
core   +2 more sources

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