Parkinson’s disease and the gastrointestinal microbiome
Journal of Neurology, 2019 Recently, there has been a surge in awareness of the gastrointestinal microbiome (GM) and its role in health and disease. Of particular note is an association between the GM and Parkinson's disease (PD) and the realisation that the GM can act via a complex bidirectional communication between the gut and the brain.
Michal Lubomski +6 more
openaire +3 more sources
Microbiome and metabolome insights into the role of the gastrointestinal-brain axis in neurodegenerative diseases: unveiling potential therapeutic targets [PDF]
arXiv, 2022 Due to the aging of the world population and westernization of lifestyles, the prevalence of neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD) is rapidly rising and is expected to put a strong socioeconomic burden on health systems worldwide.
arxiv
Towards large-cohort comparative studies to define the factors influencing the gut microbial community structure of ASD patients. [PDF]
, 2015 Differences in the gut microbiota have been reported between individuals with autism spectrum disorders (ASD) and neurotypical controls, although direct evidence that changes in the microbiome contribute to causing ASD has been scarce to date.
Debelius, Justine +5 more
core +3 more sources
Development of the preterm infant gut microbiome: a research priority. [PDF]
, 2014 The very low birth weight (VLBW) infant is at great risk for marked dysbiosis of the gut microbiome due to multiple factors, including physiological immaturity and prenatal/postnatal influences that disrupt the development of a normal gut flora. However,
Ashmeade, Terri L +5 more
core +3 more sources
Carnitine metabolism to trimethylamine by an unusual Rieske-type oxygenase from human microbiota [PDF]
, 2014 Dietary intake of L-carnitine can promote cardiovascular diseases in humans through microbial production of trimethylamine (TMA) and its subsequent oxidation to trimethylamine N-oxide (TMAO) by hepatic flavin-containing monooxygenases.
Bugg, Tim +6 more
core +1 more source
Prebiotics and the poultry gastrointestinal tract microbiome
Poultry Science, 2020 Feed additives that can modulate the poultry gastrointestinal tract and provide benefit to bird performance and health have recently received more interest for commercial applications. Such feed supplements offer an economic advantage because they may directly benefit poultry producers by either decreasing mortality rates of farm animals, increasing ...
Steven C. Ricke +4 more
openaire +4 more sources
— Invited Review — Metagenomic investigation of gastrointestinal microbiome in cattle [PDF]
Asian-Australasian Journal of Animal Sciences, 2017 The gastrointestinal (GI) tract, including the rumen and the other intestinal segments of cattle, harbors a diverse, complex, and dynamic microbiome that drives feed digestion and fermentation in cattle, determining feed efficiency and output of pollutants. This microbiome also plays an important role in affecting host health.
Minseok Kim, Zhongtang Yu, Tansol Park
openaire +4 more sources
Statistical Methods for Microbiome Analysis: A brief review [PDF]
arXiv, 2023 Recent attacks of various viruses with having deep and extensive impact at a global scale has warranted that microbiome be studied extensively and in a robust analytic framework. Microbiome typically refers to the collective genomes of such organisms, although it could also refer to the collection of the organisms by themselves.
arxiv
Bugs as Features (Part I): Concepts and Foundations for the Compositional Data Analysis of the Microbiome-Gut-Brain Axis [PDF]
, 2022 There has been a growing acknowledgement of the involvement of the gut microbiome - the collection of microbes that reside in our gut - in regulating our mood and behaviour. This phenomenon is referred to as the microbiome-gut-brain axis. While our techniques to measure the presence and abundance of these microbes have been steadily improving, the ...
arxiv +1 more source
The Brain-Gut-Microbiome Axis. [PDF]
, 2018 Preclinical and clinical studies have shown bidirectional interactions within the brain-gut-microbiome axis. Gut microbes communicate to the central nervous system through at least 3 parallel and interacting channels involving nervous, endocrine, and ...
Kalani, Amir +3 more
core +2 more sources