Paraneoplastic syndromes associated with tumors of the digestive system
Universidad Médica Pinareña, 2021 Introduction: paraneoplastic syndromes are sets of signs and symptoms affecting cancer patients, which do not depend directly on the tumor. Objective: to describe paraneoplastic syndromes associated with digestive system tumors.
Roxana Vitón-Moreno +1 more
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p53 Immunohistochemistry Patterns Are Surrogate Biomarkers for TP53 Mutations in Gastrointestinal Neuroendocrine Neoplasms [PDF]
, 2021 Junjie Li +8 more
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Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations
Advanced Functional Materials, EarlyView.Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan +4 more
wiley +1 more source
Genomic dissection of gastrointestinal and lung neuroendocrine neoplasm
Chinese Journal of Cancer Research, 2019 Neuroendocrine neoplasms (NENs) are relatively rare and heterogeneous malignancies with two major subtypes: low-grade neuroendocrine tumor (NET) and high-grade neuroendocrine carcinoma (NEC). Comprehensive molecular characterization of NENs is needed to refine our understanding of the biological underpinnings of different NEN subtypes and to predict ...
Xue Wu +11 more
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Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function
Advanced Functional Materials, EarlyView.Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh +3 more
wiley +1 more source
Diagnosis and therapy of neuroendocrine neoplasms of the gastrointestinal tract
Family Medicine & Primary Care Review, 2016 A neuroendocrine neoplasm (NEN) is a tumor that originates in neuroendocrine cells capable of producing peptides or amines. Neuroendocrine neoplasms of the digestive system are also referred to as gastroenteropancreatic neuroendocrine neoplasms (GEP NEN) and constitute a heterogeneous group of growths originating from at least 15 types of specialized ...
Andrzej Deptała, Aleksandra Czerw
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Metal Nanoclusters for Cancer Imaging and Treatment
Advanced Functional Materials, EarlyView.This review aims to provide a comprehensive summary and discussion of the core–shell design capabilities of metal nanoclusters (NCs) at the atomic level for cancer imaging and treatment. It offers essential insights into the design principles of metal NCs while also encouraging the exploration of other nanomaterials and their potential theranostic ...
Haiguang Zhu +5 more
wiley +1 more source
Periampullary duodenal schwannoma mimicking ampullary neoplasm
Radiology Case Reports, 2020 Schwannomas are neurogenic tumors that arise from Schwann cells in the neural sheath. Gastrointestinal schwannomas occur most often in the stomach, followed by the colon and the rectum.
Marly Pierina Rubio Sierra, MD +4 more
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Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Advanced Functional Materials, EarlyView.Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Clinical Data-CT Radiomics-Based Model for Predicting Prognosis of Patients with Gastrointestinal Pancreatic Neuroendocrine Neoplasms (GP-NENs) [PDF]
, 2022 Peng An +9 more
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