Results 131 to 140 of about 106,101 (300)

Gastrointestinal stromal tumor of the rectum with scapular metastasis: a case report

open access: yesJournal of Medical Case Reports, 2012
Introduction Gastrointestinal stromal tumors are rare tumors. They commonly metastasize within the abdominal cavity, particularly to the liver. Less commonly, metastases can be found in the bone.
Selcukbiricik Fatih   +6 more
doaj   +1 more source

Syndromic gastrointestinal stromal tumors

open access: yesHereditary Cancer in Clinical Practice, 2016
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of gastrointestinal tract. They feature heterogeneous triggering mechanisms, implying relevant clinical differences. The vast majority of GISTs are sporadic tumors. Rarely, however, GIST-prone syndromes occur, mostly depending on heritable GIST predisposing molecular ...
openaire   +3 more sources

Adherens junction protein expression is associated with poor response to neoadjuvant FLOT chemotherapy and pro‐inflammatory tumor microenvironment in esophageal adenocarcinoma

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Esophageal adenocarcinoma (EAC) is an aggressive cancer with poor survival and variable response to perioperative chemotherapy. Although histopathological features correlate with outcomes, the relationship specifically between adherens junction (AJ) protein expression and treatment response in EAC remains uncertain.
Bastian Grothey   +8 more
wiley   +1 more source

Urokinase Plasminogen Activator Receptor‐Associated Protein (uPARAP) as a Potential Next Generation Molecular Target for Treatment of Gastrointestinal Stromal Tumors (GIST)

open access: yesInternational Journal of Cancer, EarlyView.
A key component of the collagen internalization and lysosomal degradation cellular machinery, uPARAP may contribute to cancer progression. Here, the authors explored the expression of uPARAP in gastrointestinal stromal tumors using well‐annotated clinical patient samples and specimens from cell line‐ and patient‐derived xenografts.
Chao‐Chi Wang   +10 more
wiley   +1 more source

Development and Release of the Munich UICC Staging Tool (MUST): Advancing UICC Staging in Real‐World Data With Insights From Pancreatic and Stomach Cancer

open access: yesInternational Journal of Cancer, EarlyView.
Accurate cancer staging is essential for cancer research and treatment evaluation. However, real‐world data often include incomplete or inconsistent UICC staging classifications. The presented Munich UICC Staging Tool (MUST) automates UICC stage derivation from TNM classifications and tumor characteristics, incorporating novel real‐world data rules to ...
Brigitte Kühnel   +18 more
wiley   +1 more source

Derivation and Validation of a Predictive Model for Advanced Colorectal Neoplasia Among Average‐Risk Adults in China

open access: yesInternational Journal of Cancer, EarlyView.
Efficient pre‐colonoscopy risk stratification tools are needed, especially in China. Using multicenter colorectal cancer screening data from Shandong Province, the authors developed and validated a risk prediction model for advanced colorectal neoplasia in asymptomatic individuals using sociodemographic characteristics, lifestyle factors, and medical ...
Yan Liu   +6 more
wiley   +1 more source

bacNeo: A Computational Toolkit for Identifying Bacteria‐Derived Neoantigens in Human Cancers

open access: yesiMetaMed, EarlyView.
We present bacterial neoantigen (bacNeo), a multi‐omics‐based computational software to classify bacterial components (BACC), type bacteria‐bound HLA alleles (BACH), and prioritize bacterial peptides as neoantigens (BACP). Bacterial neoantigen potential is quantified by score for peptide antigenicity recognition & kinetics (SPARK), enabling ...
Yunzhe Wang   +5 more
wiley   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

open access: yesiNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid   +4 more
wiley   +1 more source

Uptake of 18F-AlF-NOTA-octreotide PET/CT in gastrointestinal stromal tumors

open access: yesEJNMMI Reports
Gastrointestinal stromal tumors (GISTs) are rare stromal neoplasms that predominantly arise in the gastrointestinal tract. 18F-AlF-NOTA-octreotide (18F-OC) is a novel molecularly targeted probe that specifically binds to tumors expressing somatostatin ...
Xiaodan Xu   +4 more
doaj   +1 more source

Tubular Krukenberg Tumor with an Occult Primary [PDF]

open access: yes, 2011
Tubular Krukenberg tumor with an occult primary can cause problems in histopathologic diagnosis, by mimicking primary ovarian tumors. We present one such occurrence in a 32year old female who underwent surgery for bilateral malignant ovarian tumor. Gross
Kaur, N, Kaushal, V, Mardi, K
core   +1 more source

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